Clinical trials: Respiratory Sounds
Covid19
Cough Sound Recordings to Understand COVID-19-like Symptom Progression to Understand COVID-19-like Symptom Progression
Decentralized clinical study designed to collect further cough sounds, self-reported symptoms, and medical treatment questionnaires from participants enrolled on the COVID-Cough Study ("Study 1").
- Trial name
- NCT04989452
- Testing
- Recordings of cough sounds from adults
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ResApp Health Limited
Snoring
Study of Nasal Airflow Pressure Optimization to Resolve Excessive Snoring
This is a prospective, interventional, study in which patients with a history of habitual snoring to determine whether low pressure nasal continuous airway pressure can reduce the frequency, duration or intensity of snoring in…
- Trial name
- SNORE (NCT01949584)
- Testing
- nasal continuous positive airway pressure less than or equal to 6 cm H2O
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- inSleep Technologies, LLC
Wheezing, Recurrent Respiratory Tract Infections
Evaluate the Effect of Nasal Spray in the Prevention of RTI in Children With Pre-school Wheezing
To determine whether or not preventive administration of resveratrol in the form of a nasal spray is effective in reducing the number of asthma exacerbations typical of preschool wheezing children who develop viral infections.
- Trial name
- NCT05684848
- Testing
- Resveratrol + CMG, Isotonic solution
- Where
- Italy
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Noos S.r.l.
Asthma, Asthma in Children
Wearable Auscultation Device Validation in Children
This observational clinical study is an evaluation of a diagnostic tool through comparison. Similar to a validation study, the output of the RESP device will be compared to physician auscultation, surrogated by having an…
- Conditions
- Asthma, Asthma in Children, Wheezing, Pediatric Asthma
- Trial name
- NCT06112080
- Testing
- RESP™ Biosensor
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Strados Labs, Inc.
Wheezing, Reactive Airway Disease
A Study of the Pharmacokinetics, Safety and Tolerability of Single Doses of VR647 Inhalation Suspension Administered Using the VR647 Inhalation System in Children With Wheezing, Reactive Airway Disease or Mild Asthma
The primary objective of this study is to evaluate budesonide levels in the blood following inhalation of single doses of VR647 Inhalation Suspension in children with wheezing, reactive airway disease or mild asthma using a…
- Conditions
- Wheezing, Reactive Airway Disease, Mild Asthma
- Trial name
- NCT03421730
- Testing
- VR647 Inhalation Suspension (budesonide) 1 mg/2 mL delivered by the VR647 Inhalation System, 1 mg/2 mL Pulmicort Respules delivered by a conventional jet nebulizer
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- Vectura Limited
Snoring, Sleep Apnea, Obstructive
Efficacy of Intra-oral Neuromuscular Stimulation Training on Snoring and Mild Sleep Apnoea
It has been shown that a common cause for snoring and throat obstruction (obstructive sleep apnoea (OSA)) is excessive loss of muscle tone in the throat when the investigators go to sleep.
- Trial name
- NCT04392765
- Testing
- eXciteOSA
- Where
- 6 sites in Canada, Germany and 2 more
- Volunteers
- 200 people
- Sponsor
- Signifier Medical Technologies
Snoring
Efficacy Study of the Medical Device TRP Snorless™ in the Treatment of Snoring
The Tongue Right Positioner (TRP Snorless™) is a medical device designed to restore physiological tongue positions when functioning or at rest and increase tongue muscles tone.
- Trial name
- SCORED (NCT03222193)
- Testing
- TRP
- Where
- Czechia
- Volunteers
- 35 people
- Sponsor
- Tongue Laboratory
Sleep Apnea, Obstructive, Chronic Obstructive Pulmonary Disease
SNORE (Smartphone Analyses of Nocturnal Obstruction by Respiratory Evaluation) SOUNDS
This is a prospective multipart clinical performance study to compare the ability of the SnoreSounds algorithm with polysomnography (PSG) and a type III Home Sleep Testing (HST) device to identify patients with obstructive sleep…
- Trial name
- SNORESOUNDS (NCT03288376)
- Where
- 3 sites in United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Incyphae, Inc.
Snoring
Pilot Study of cNEP for the Treatment of Snoring
This pilot study will examine the efficacy and safety of continuous negative external pressure ("cNEP") for the treatment of chronic snoring in people without obstructive sleep apnea.
- Trial name
- NCT02767843
- Testing
- continuous negative external pressure (cNEP)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Sommetrics, Inc.
Obstructive Sleep Apnea, Snoring
A Trial to Evaluate a Device for the Treatment of OSA and Snoring
To evaluate the safety and efficacy of the Tongue Advancement Retainer Device in treating subjects with Obstructive Sleep Apnea (OSA) and snoring.
- Trial name
- OPEN (NCT01772017)
- Testing
- Tongue Advancement Retainer Device
- Where
- 3 sites in United States, Australia
- Volunteers
- 15 people
- Sponsor
- Sleepy, Inc
Asthma, COPD
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.
- Trial name
- NCT05145894
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 200 people
- Sponsor
- Healthy Networks
Snoring
Snoring Intervention Via Elevoplasty in a Non-surgical Clinical Environment
Single Group Compared to Baseline, Non-Randomized, Multi-Center, Prospective Safety \& Efficacy Study
- Trial name
- SILENCE (NCT03083106)
- Testing
- Elevoplasty
- Where
- 6 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zelegent, Inc.
Wheezing, Rhonchi
Clinical Evaluation of AI-aided Auscultation With Automatic Classification of Respiratory System Sounds
In the present trial, the StethoMe electronic stethoscope will be used for pulmonary auscultation and recording of lung sounds in the pediatric study population.
- Conditions
- Wheezing, Rhonchi, Crackle, Lung Sound
- Trial name
- AIR (NCT04208360)
- Testing
- StethoMe stethoscope
- Volunteers
- 84 people
- Sponsor
- StethoMe
Snoring, Obstructive Sleep Apnea
Safety, and Tolerability of the ZENS Device (PLUTO)
The primary objective of the PLUTO study is to evaluate the safety and tolerability of the ZENS transcutaneous nerve stimulator device in primary snorers and those with mild obstructive sleep apnea.
- Trial name
- NCT04063917
- Testing
- ZENS
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zennea Technologies Inc.
Emphysema, COPD
Distribution of Regional Lung Function by Vibration Response Imaging
Assessment of regional contribution of different areas of the lung to its integrated function is often required, such as prior to lung resection in the presence of tumor or emphysema.
- Trial name
- NCT01229020
- Testing
- Observational study - no intervention
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Deep Breeze
Asthma
A Study of the Treatment-Sparing Effects of AEROVANT™ AER 001 Inhalation Powder in Asthma Patients, AEROTRIAL
A multi-center, Phase IIb, double-blind, randomized, placebo controlled, parallel-group, repeated-dose study in male and female patients with moderate to severe asthma in which patients will be stabilized on AEROVANT then doses…
- Trial name
- NCT00801853
- Testing
- Aerovant
- Where
- 71 sites in United States, Hungary and 2 more
- Volunteers
- 424 people
- Sponsor
- Aerovance, Inc.
Lung Diseases
Data Collection Using Eko Digital Devices in a Clinical Setting
The purpose of this research is to prospectively train and validate an artificial intelligence machine learning (ML) algorithm to detect the presence of adventitious lung sounds in adults.
- Trial name
- NCT07227376
- Testing
- Eko digital stethoscopes
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Eko Devices, Inc.
Asthma
Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.
The main objective of this study is to evaluate the efficacy and safety of the Armstrong's Epinephrine HFA-MDI (E004) formulation, in comparison to the Placebo (Placebo-HFA) and an Active Control (Epinephrine CFC-MDI), and to…
- Trial name
- NCT01025648
- Testing
- E004 (epinephrine inhalation aerosol), 90 mcg/actuation, E004 (epinephrine inhalation aerosol), 125 mcg, E004 (epinephrine inhalation aerosol), 220 mcg
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Covid19
A Pilot Study for the Collection Of Vocalized, Individual Digital Cough Sound Recordings to Screen for COVID-19
Decentralized clinical study designed to collect cough sounds and self-reported symptoms alongside a COVID-19 realtime quantitative polymerase chain reaction (rt-qPCR) test.
- Trial name
- COVID-Cough (NCT04864535)
- Testing
- Recordings of cough sounds from adults
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- ResApp Health Limited
Sleep Apnea, Snoring
Substantial Equivalence of iSlpr™ and SomnoDent® Classic in the Treatment of Snoring and Mild to Moderate Sleep Apnoea.
The study is a thirty three week, prospective, open-label, randomized, parallel-group non-inferiority study. The study aims to investigate the Substantial Equivalence of a novel mandibular device called iSlpr™, produced by…
- Trial name
- NCT04250584
- Testing
- iSlpr™, SomnoDent® Classic
- Volunteers
- 66 people
- Sponsor
- BioAnalytics Holdings Pty Ltd