Clinical trials: Respiratory Therapy Techniques
Pneumothorax
Video-assisted Thoracic Surgery (VATS) Versus Axillary Mini-thoracotomy for the Treatment of Recurrent Spontaneous Pneumothorax
The investigators conducted a prospective randomized study to compare axillary minithoracotomy versus a modified two-port thoracoscopic technique for surgical pleurodesis in patients with recurrent spontaneous pneumothorax…
- Trial name
- NCT01192217
- Testing
- Modified thoracoscopic technique, Axillary mini-thoracotomy
- Where
- Greece
- Volunteers
- 66 people
- Sponsor
- AHEPA University Hospital
Asthma
Asthma Treatment: Buteyko Breathing Technique
This study aimed to evaluate the effects of BBT training on asthma control, quality of life, and pulmonary function among asthma patients.The findings suggest that BBT may be a potentially effective complementary approach.
- Trial name
- NCT07105306
- Testing
- Buteyko Breathing Technique Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Seçil Beyece İncazli
Dysphonia
Comprehensive Voice Rehabilitation Program Compared With Vocal Function Exercises
The purpose of this study is to evaluate the effectiveness and safety of the Comprehensive Voice Rehabilitation Program compared with Vocal Function Exercises in behavioral dysphonia.
- Trial name
- Voicetherapy (NCT02409758)
- Testing
- Voice therapy
- Volunteers
- 106 people
- Sponsor
- Federal University of São Paulo
Bronchiectasis, Bronchiectasis With Acute Exacerbation
Comparing Active Cycle of Breathing Techniques (ACBT) and Aerobika in Treating Bronchiectasis in Korea
Title: Comparison of Effectiveness Between Active Cycle of Breathing Techniques (ACBT) and Oscillating Positive Expiratory Pressure (OPEP, Aerobika) Device Assisted Treatment in Patients With Bronchiectasis in Korea: A Randomized…
- Trial name
- NCT07037303
- Testing
- Active Cycle of Breathing Technique (ACBT) and Oscillatory Positive Expiratory Pressure (OPEP) group, Active Cycle of Breathing Technique (ACBT) group
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chungbuk National University Hospital
Heart Failure, Congestive
Evaluation of MRI Measures of Lung Water With Posture Changes in Healthy Volunteers and in Patients With Cardiac Failure
The aim of this study is to establish a model for the evaluation of drug targets using postural measures to induce changes in lung water concentration as assessed by MRI.
- Trial name
- NCT01277679
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cystic Fibrosis
Do Physiotherapy Techniques Improve Posture During Admission for a Chest Infection in Adults With Cystic Fibrosis?
Hypothesis: The addition of a series of musculoskeletal techniques to normal optimal care for the treatment of a respiratory exacerbation in inpatient adults with cystic fibrosis, will lead to further improvements in pain…
- Trial name
- NCT00806884
- Testing
- Physiotherapy Musculoskeletal Treatment, Control group measurements
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Subcutaneous Emphysema, Covid19
Negative Pressure Therapy, Minimally Invasive and Accessible Technique in the Treatment of Massive Subcutaneous Emphysema in COVID-19 or Non Infected Critical Patients
Background Numerous surgicals treatments have been described for the massive subcutaneous emphysema; however, some of these techniques cannot be carried out in a critical care unit and they are related with high morbidity and…
- Trial name
- NCT04840953
- Testing
- Vçac
- Where
- Spain
- Volunteers
- 2 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Telehealth, Copd
Evaluating Chronic Obstructive Pulmonary Disease (COPD) Patients' Treatment Compliance and Quality of Life Via Telemedicine
The Covid-19 pandemic has disrupted the follow-up and treatment processes for patients, and telemedicine has emerged as an important alternative method.
- Trial name
- NCT06477328
- Testing
- Telemedicine
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ankara Etlik City Hospital
Lung Neoplasms, Pulmonary Surgical Procedures
Staple-line Reinforcement for Prevention of Pulmonary Air Leakage
The aim of this study is to compare the efficacy of FORESEAL with stapling alone or associated with tissue sealant or glue in terms of air leakage duration after lung resection for cancer.
- Conditions
- Lung Neoplasms, Pulmonary Surgical Procedures, Surgical Staplers, Tissue Adhesives
- Trial name
- SPIRAL (NCT00925444)
- Testing
- FOREseal, Stapling
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intubating Conditions, Fasciculations
Muscle Relaxation for Short Procedures
Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application of low-dose rocuronium, reversed by low-dose sugammadex.
- Conditions
- Intubating Conditions, Fasciculations, Postoperative Myalgia, Patient Satisfaction
- Trial name
- NCT01902641
- Testing
- Succinylcholine, Rocuronium/Sugammadex, Rocuronium
- Where
- Germany
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis)
Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS
This study evaluates potential of music therapy treatment to support breathing, speech, swallow and cough of persons with amyotrophic lateral sclerosis (ALS).
- Conditions
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis), Dysarthria, Flaccid, Dysarthria, Spastic
- Trial name
- NCT03604822
- Testing
- Music therapy
- Where
- 2 sites in Russia, United Kingdom
- Volunteers
- 8 people
- Sponsor
- Alisa Apreleva
Pneumothorax, Hemothorax
Evaluating Improvised Chest Drainage Techniques in Conflict Zones
This study examines the use of improvised chest drainage systems in managing chest trauma at Wad Madani Teaching Hospital, a low-resource and conflict-affected setting.
- Conditions
- Pneumothorax, Hemothorax, Thoracic Trauma, Flail Chest
- Trial name
- NCT06683976
- Where
- Sudan
- Volunteers
- 180 people
- Sponsor
- Sudan Medical Specialization Board
ECMO Treatment, ARDS
Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"
In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels.
- Conditions
- ECMO Treatment, ARDS, Pneumonia, Intensive Care
- Trial name
- NCT06593717
- Testing
- Transthoracic Echocardiography, Uncalibrated Pulse Contour Analysis, Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Respiratory Insufficiency
Efficacy of Different Respiratory Methods in Intensive Care
Peripheral oxygen saturation, non-invasive blood pressure, heart rate, respiratory rate and respiratory rate are routinely used in our intensive care unit in the follow-up of patients.
- Trial name
- NCT04108585
- Testing
- HFO therapy, CPAP therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Trakya University
Chronic Obstructive Pulmonary Disease (COPD), Airway Clearance
Oscillating Positive Expiratory Pressure Therapy Versus Autogenic Drainage in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a long-term lung condition that causes breathing difficulty, cough, and sputum production.
- Trial name
- OPEP-AD-COPD (NCT07402850)
- Testing
- Oscillating Positive Expiratory Pressure Therapy, Autogenic Drainage
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Adnan Hashim
SARS-CoV2 Infection, Viral Load
Viral Kinetics of SARS-CoV-2 in Patients With COVID-19 in the Intensive Care Unit Undergoing Dental Procedures
The prevalence and clinical relevance of viremia in patients with COVID-19 have not been well investigated. Seeking to understand the need for dentistry to perform bloody procedures in critically ill patients with COVID-19…
- Conditions
- SARS-CoV2 Infection, Viral Load, Oral Diseases, Dental Treatment
- Trial name
- VKSPCICUDP (NCT05311410)
- Testing
- Non-bloody dental procedures (control group), Bloody dental procedures (study group)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
COPD, Asthma
Video-based Teach-to-goal Intervention on Inhaler Technique on Jordanian Adults With Asthma and COPD
This study was an interventional educational study that was intended to find out the effect of a video based inhaler technique education on improving inhaler technique mastery, disease control, medication adherence and patient…
- Conditions
- COPD, Asthma, Inhaled Steroid Dependent Asthma
- Trial name
- NCT05664347
- Testing
- Verbal teach to goal education, Video based teach to goal education
- Where
- Jordan
- Volunteers
- 154 people
- Sponsor
- University of Jordan
Cancer of Lung
4D CBCT and Intrafractional Imaging for the Determination of the Most Representative 4D Simulation Planning Technique for Lung SBRT Technique Patients
The researchers plan to investigate two ways of visualizing and planning to account for the respiratory motion which takes place while treating lung tumors with radiation therapy.
- Trial name
- NCT04717804
- Testing
- AIP CT, FB (Free-Breathing) CT
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Alpha 1-Antitrypsin Deficiency
Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
Individuals with a deficiency of the Alpha 1-antitrypsin (AAT) protein are at risk for developing emphysema and liver damage. Researchers have developed a way to introduce normal AAT genes into muscle cells so that the AAT…
- Trial name
- NCT00377416
- Testing
- rAAV2-CB-hAAT Gene Vector
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Massachusetts, Worcester
Primary Spontaneous Pneumothorax (PSP), Conservative Management (Active Observation)
Conservative Management in Primary Spontaneous Pneumothorax: a Multicenter Randomized Non-inferiority Study
The goal of this randomized clinical trial is to find out whether a conservative management strategy (active observation without an initial invasive procedure) can treat as effectively as the standard treatment with chest tube…
- Trial name
- CONNEP (NCT07331805)
- Testing
- Conservative management (active observation), Chest tube drainage
- Volunteers
- 436 people
- Sponsor
- Corporacion Parc Tauli