Clinical trials: Rest
Autonomous Sensory Meridian Response, Audiobook
Effects of ASMR on the Default Mode Network
This study investigates the effects of Autonomous Sensory Meridian Response (ASMR) stimulation on resting-state brain networks. Therefore, two resting-state fMRI scans are measured in healthy adults.
- Trial name
- NCT05266508
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Vocal Cord Paralysis
Voice Rest and Injection Laryngoplasty
The purpose of this study is to evaluate the subjective, objective, and aerodynamic impact of voice rest following injection augmentation and compare the outcomes to patients with no post-procedure voice restrictions.
- Trial name
- NCT05542550
- Testing
- Voice Rest, No Voice Rest
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Bariatric Surgery Candidate, Obesity
The Effect of Exercise in Patients Awaiting Bariatric Surgery
The aim of this project is to understand the impact of a four week preoperative exercise programme on fitness and metabolic rate and weight before surgery.
- Trial name
- BariPrehab (NCT05235945)
- Testing
- Online exercise intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Mechanical Ventilation, Dexmedetomidine
Dexmedetomidine vs Midazolam on Resting Energy Expenditure in Critically Ill Patients
The aim of this study is to compare the effect of dexmedetomidine on resting energy expenditure in relation to the midazolam in critically ill patients using indirect calorimetry
- Conditions
- Mechanical Ventilation, Dexmedetomidine, Midazolam, Sedation
- Trial name
- NCT03030911
- Testing
- Dexmedetomidine, Midazolam, Fentanyl
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Hemodynamics
The Effect of Age on the Hemodynamic Response During Rest and Exercise in Healthy Humans
Primary: To observe how hemodynamic parameters are affected by age during rest and exercise in healthy humans. Furthermore, how an acute fluid challenge changes hemodynamic parameters.
- Trial name
- HemReX (NCT01974557)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Finn Gustafsson
Cerebral Palsy, Autonomic Nerveus System
BioFeedBack Breathing Training Influence Cardiac Autonomic Nervous System in Children With Cerebral-Palsy.
The effect of breathing biofeedback training to influence the function of the cardiac autonomic nervous system at rest and in activity in children with cerebral palsy.
- Trial name
- NCT01872507
- Testing
- Biofeedback training
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Parkinson's Disease, Multiple System Atrophy
Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Syndromes
Parkinsonian syndrome is clinically characterized by the presence of resting tremor, rigidity, bradykinesia and postural instability.
- Conditions
- Parkinson's Disease, Multiple System Atrophy, Progressive Supranuclear Palsy, Vascular Parkinsonism
- Trial name
- PARKIMAGE (NCT02445469)
- Testing
- MRI exam of the brain
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Pulmonary Hypertension
Acute Exposure of Simulated Hypoxia on Cognitive Function
Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to simulated altitude (FiO2:15.1, equivalent to 2500m above sea level) on cognitive functions.
- Trial name
- NCT03637127
- Testing
- Simulated Altitude (FiO2: 15.1%)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Hypertension, Cardiovascular Diseases
Zero to Five Automated Oscillometric Office Blood Pressure (AOBP) Measurement
The Hypertension Canada Clinical Practice Guidelines for blood pressure measurement using AOBP recommend against any wait time prior to commencing the measurement. The recent AHA guidelines however call for a 5-minute rest first.
- Trial name
- NCT03732924
- Testing
- Zero to Five Automated Oscillometric Office Blood Pressure (AOBP) Measurement
- Where
- Canada
- Volunteers
- 618 people
- Sponsor
- Sunnybrook Health Sciences Centre
Preterm Birth, Cervical Insufficiency
Bed Rest With a Short Cervix on Preterm Birth
Maternal AR has long been used to prevent PTB. However, definitions of AR vary widely, ranging from complete bed rest to partial limitation of physical activity for one or more hours daily.
- Conditions
- Preterm Birth, Cervical Insufficiency, Bed Rest, Pregnancy Complications
- Trial name
- BEWISE (NCT07577388)
- Testing
- Activity Restriction, No Activity Restriction
- Volunteers
- 6,000 people
- Sponsor
- Julie Glavind
Anorexia in Adolescence, Anorexia Nervosa
3-Dimensional Optical Scanning to Assess and Monitor Malnutrition in Eating Disorders (3D-ED) Study
People with anorexia nervosa often become medically unstable because of severe malnutrition and require hospitalization for nutritional rehabilitation.
- Conditions
- Anorexia in Adolescence, Anorexia Nervosa, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- 3D-ED (NCT07726524)
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Francisco
Pulmonary Hypertension
Acute Exposure to High Altitude on Pulmonary Artery Pressure and Right Heart Function (Echo) Under Exercise
Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude (2500m above sea level) on pulmonary artery pressure and right heart function (Echo) under exercise.
- Trial name
- NCT03637179
- Testing
- Assessment at Low Altitude (470m above sea level), Exposure to High Altitude (2500m above sea level)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Psychological Wellness
Resilient Students Training (ReST) : A Pilot RCT
Resilience is the ability to survive and thrive despite significant adversity. Trials of resilience-promoting interventions for university students have shown significant improvements in students' resilience and reductions in…
- Trial name
- ReST (NCT06157931)
- Testing
- Resilient Student Training intervention (ReST)
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Aortic Valve Stenosis, Coronary Artery Disease
Correlation of FFR and iFR With Cardiac PET Perfusion in Patients With Severe Aortic Valve Stenosis
Aortic valve stenosis (AS) affects 2-7% of persons > 65 years, symptoms include: angina and dyspnea, dizziness and syncope. Coincidence of coronary artery disease (CAD), also presenting with angina and dyspnea, in patients with…
- Trial name
- TAVI PET (NCT04882488)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Diabetes Mellitus, Type 2, Metabolic Cardiomyopathy
Cardiac Rest and Stress Metabolism in Patients With Type 2 Diabetes
The number of people with diabetes is rising. One of the major causes of premature death in diabetes is heart failure (HF). This is when the heart cannot pump blood effectively, and this may be related to abnormalities in energy…
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Cardiomyopathy, Metabolic Disturbance, Fatty Acid Oxidation Disorder
- Trial name
- CardioMET (NCT04009642)
- Testing
- Surely observational based on disease state
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- University of Leicester
Depression, Sleep Disorders, Circadian Rhythm
Sleep-Wake Patterns on Illness Trajectories and Treatment Response in MDD
The proposed study will include a longitudinal ecological study (Study 1) and a randomised controlled trial (Study 2). The aims will be to (1) identify the sleep-wake profiles in individuals with MDD through clustering; (2)…
- Trial name
- NCT06181110
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Total Knee Arthroplasty
REST-Knee: A Pilot RCT of 72-Hour Knee Immobilization and Pain Outcomes
Postoperative pain following total knee arthroplasty (TKA) is often difficult to manage, particularly with the increasing use of outpatient surgery where patients recover at home.
- Trial name
- REST-Knee (NCT07511842)
- Testing
- Knee Extension Brace (Zimmer-type), Early Mobilization (Standard Care)
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Université de Sherbrooke
Stable Angina, Hypertension
Achievement of Goal Resting Heart Rate on B-blockers in Patients With Stable Angina and Hypertension
This is a multicenter survey of Russian data on target heart rate achievement in patients with stable angina and arterial hypertension who are currently treated with beta-blockers for at least 2 months and with no dose change for…
- Trial name
- Athena (NCT01321242)
- Where
- 6 sites in Russia
- Volunteers
- 400 people
- Sponsor
- AstraZeneca
Preterm Premature Rupture of the Membranes, Physical Activity
A Comparison of Bed Rest Versus Moderate Activity in Preterm Premature Rupture of Membranes (PPROM)
Bed rest has been a commonly prescribed intervention for high risk pregnancies, despite the lack of data to support its benefits, and increasing evidence pointing to potential harms.
- Trial name
- PACT (NCT02327637)
- Testing
- Moderate Activity
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, San Diego
Bed Rest, Pregnancy
Physical Activity in Bed Rest Hospitalized High-Risk Pregnant Women.
This study aims to evaluate the impact of a specifically designed exercise program for hospitalized high-risk pregnant individuals on bed rest.
- Conditions
- Bed Rest, Pregnancy, Pregnancy Complications
- Trial name
- BedRest-1 (NCT07657000)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Hospital Clinic of Barcelona