Clinical trials: Rest, open to volunteers
Bariatric Surgery Candidate, Obesity
The Effect of Exercise in Patients Awaiting Bariatric Surgery
The aim of this project is to understand the impact of a four week preoperative exercise programme on fitness and metabolic rate and weight before surgery.
- Trial name
- BariPrehab (NCT05235945)
- Testing
- Online exercise intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Resting Metabolic Rate, Energy Metabolism
Within-Individual Variability of Resting Metabolic Rate Over 12 Weeks
This prospective observational study aims to characterize within-individual variability in resting metabolic rate (RMR) over a 12-week period using high-frequency repeated measurements under standardized conditions.
- Trial name
- NCT07628764
- Testing
- Repeated Measurement of Resting Metabolic Rate
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Postmenopause, Energy Expenditure
Resting Energy Expenditure in Postmenopausal Women
Obesity and its associated comorbidities are rising at an alarming rate, particularly among postmenopausal women. Menopause, characterized by a decline in estradiol and progesterone levels, is often accompanied by weight gain.
- Conditions
- Postmenopause, Energy Expenditure, Hormone Replacement Therapy
- Trial name
- MenoBOLISM (NCT06905886)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Obesity
Transduction of Sympathetic Neural Activity in Human Obesity Without Hypertension
In addition to chronically elevated MSNA, there is a growing recognition that hypertension in states of insulin resistance and obesity may also be attributed to an increased vascular sensitivity to MSNA (1, 2, 13, 36-38).
- Trial name
- NCT06626113
- Testing
- ascorbic acid
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Kansas Medical Center
Depression
rTMS Response Trajectories in Depression
Notwithstanding the cumulative evidence on the safety and efficacy of transcranial magnetic stimulation in depression care, the non-response rate to transcranial magnetic stimulation (TMS) amongst treatment-resistant depression…
- Trial name
- NCT03348761
- Testing
- rTMS group
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Osteoporosis
Resting-state Imaging and OSteoporosiS
This study will be conducted in 20 postmenopausal healthy volunteers, 20 postmenopausal osteoporotic patients with fracture and 20 postmenopausal osteoporotic women without fracture, in order to compare functional connectivity…
- Trial name
- ROSS (NCT07030205)
- Testing
- Blood sample, Bone density exam, Tests and questionnaires of study
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Cerebral Palsy
How Much Virtual Reality Intervention Improve the Balance of Patients With Cerebral Palsy
The purpose of this clinical study is to investigate how effective virtual reality applications are in adult cerebral palsy rehabilitation.
- Trial name
- NCT06769178
- Testing
- Virtual Reality based
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Yeditepe University
Cerebral Small Vessel Disease, Vascular Cognitive Impairment
Personalized Intermittent Theta Burst Stimulation for Cognitive Impairment Related to Cerebral Small Vessel Disease
This study will evaluate whether personalized intermittent theta burst stimulation (iTBS), a form of noninvasive transcranial magnetic stimulation, can safely improve cognitive function in people with cognitive impairment related…
- Trial name
- NCT07891650
- Testing
- Active Personalized Intermittent Theta Burst Stimulation
- Where
- 3 sites in China
- Volunteers
- 160 people
- Sponsor
- Xuanwu Hospital, Beijing
Trigeminal Neuralgia
Resting-State fMRI Study of Functional Connectivity After Gamma Knife Radiosurgery in Trigeminal Neuralgia
Trigeminal neuralgia is a severe chronic pain condition with a major impact on quality of life. Although Gamma Knife radiosurgery is an established treatment for pharmacoresistant trigeminal neuralgia, its mechanisms of action…
- Trial name
- DOCTRINE (NCT07357025)
- Testing
- Resting-State Functional MRI
- Volunteers
- 28 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Anorexia Nervosa, Bulimia Nervosa
Functional MRI During Resting State in Patients with Eating Disorders
The goal of this observational study is to learn if clinical and neurophysiological characteristics dynamics may follow similar trends in a longitudinal characterization of patients with a diagnosis of an eating disorder.
- Trial name
- NCT06874348
- Testing
- structural and functional MRI
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Meyer Children's Hospital IRCCS
Adult Attention Deficit Hyperactivity Disorder
Effects and Mechanisms of Transcranial Direct Current Stimulation Combined With Dialectical Behavior Therapy Skills Training in Adults With Attention-Deficit/Hyperactivity Disorder
Effects and Mechanisms of Transcranial Direct Current Stimulation Combined with Dialectical Behavior Therapy Skills Training in Adults with Attention-Deficit/Hyperactivity Disorder Abstract Adult attention-deficit/hyperactivity…
- Trial name
- NCT07565402
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing Medical University
Prediabetes, Obesity & Overweight
Crocus Sativus Tepals Water Extract in Obesity and Prediabetes
The goal of this clinical trial is to determine the acute effects of ingestion of a cold aqueous extract of Crocus sativus tepals on postprandial glycemia and other indicators of metabolic health in patients with obesity and/or…
- Trial name
- ZAFRAN (NCT07261475)
- Testing
- Crocus sativus tepals cold aqueous extract, cold water
- Where
- Slovenia
- Volunteers
- 20 people
- Sponsor
- University of Primorska
Coronary Artery Disease
Resting Full-cycle Ratio (RFR)-Guided Revascularization
The purpose of this study is to compare the clinical outcomes of a 2-year follow-up to determine whether RFR-guided coronary intervention is non-inferior to FFR-guided coronary intervention in patients with intermediate coronary…
- Trial name
- NCT06075160
- Testing
- Resting full-cycle ratio (RFR)-guided revascularization, Fractional flow ratio (FFR)-guided revascularization
- Where
- South Korea
- Volunteers
- 1,167 people
- Sponsor
- Sejong General Hospital
Malnutitrion, Cancer
Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients
This study compares two methods of prescribing parenteral nutrition (PN) in adults with cancer who are unable to meet nutritional needs by oral or enteral intake.
- Trial name
- NCT07776704
- Testing
- Indirect Calorimeter, Weight-Based Parenteral Nutrition Dosing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fox Chase Cancer Center
Healthy Subjects or Volunteers
Hydrogen-Rich Water and Resting Metabolism in Young Adults
The H2REST trial is a randomized, double-blind, placebo-controlled crossover study investigating the acute effects of a single dose of hydrogen-rich water (HRW) on resting metabolism in healthy young adults.
- Trial name
- H2REST (NCT07098221)
- Testing
- Molecular Hydrogen
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad
Resting Metabolic Rate, Metabolism Disorders
Family Patterns in Resting Metabolic Rate Between Parents and Adult Children
This study examines whether resting metabolic rate (RMR)-the amount of energy the body uses at rest-is similar between biological parents and their adult children (aged 18 years and older).
- Trial name
- NCT07594613
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Urinary Incontinence , Stress
The Reliability of Pelvic Floor Measures From Ultrasound Images Acquired at Rest and During Weightlifting Tasks.
We will evaluate the inter-and intra-rater reliability of pelvic floor morphometry obtained from transperineal ultrasound images collected at rest and during standardized weight lifting tasks.
- Trial name
- LIFT (NCT07727460)
- Where
- 2 sites in Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Altitude Edema
Advair HFA in Healthy and HAPE Predisposed Subjects
The current protocol is composed of two studies. The first study is designed to carefully evaluate the safety of high-dose salmeterol/fluticasone (Advair HFA) versus placebo (hydrofluoroalkane, HFA) administration over 7 days, as…
- Trial name
- SWIFTARC (NCT06040268)
- Testing
- Advair HFA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aortic Valve Stenosis, Coronary Artery Disease
Correlation of FFR and iFR With Cardiac PET Perfusion in Patients With Severe Aortic Valve Stenosis
Aortic valve stenosis (AS) affects 2-7% of persons > 65 years, symptoms include: angina and dyspnea, dizziness and syncope. Coincidence of coronary artery disease (CAD), also presenting with angina and dyspnea, in patients with…
- Trial name
- TAVI PET (NCT04882488)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Obstructive Sleep Apnea (OSA)
Heart and Brain Blood Flow in Obstructive Sleep Apnea
Obstructive sleep apnea causes repeated pauses in breathing during sleep. Breathing efforts against an occluded airway may change how blood flows through the heart and how blood drains from the brain.
- Trial name
- OSA4DFlow (NCT07913269)
- Where
- 2 sites in Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet