Clinical trials: Resting State Networks
Obesity
Effects of the GLP-1 Exenatide on Satiety in Lean and Obese Women
Obesity is a major health problem in the US and many Western countries, with more than half of the population being overweight or obese.
- Trial name
- NCT01501084
- Testing
- Exenatide, Normal saline .2cc subcutaneous injection
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Attention Deficit/Hyperactivity Disorder
Structural and Functional Connectivity of Frontostriatal and Frontoparietal Networks as Endophenotypes of ADHD
Attention deficit/hyperactivity disorder (ADHD) is a common, impairing, clinically and genetically heterogeneous neuropsychiatric disorder with lifelong executive dysfunctions.
- Trial name
- NCT01682915
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- National Taiwan University Hospital
Encephalopathy, White Matter Hyperintensities
Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease
The purpose of this study is to extend our previous work, in which we demonstrated an increase in the internal and cross network connectivity of resting state neural networks in patients with cerebral small vessel disease by…
- Conditions
- Encephalopathy, White Matter Hyperintensities, Impaired Oxygen Delivery
- Trial name
- HBO (NCT02232958)
- Testing
- Hyperbaric Oxygen Treatment
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Brain Injuries, Acute, Brain Injuries, Traumatic
Antiseizure Medication in Seizure Networks at Early Acute Brain Injury
The goal of this clinical trial is to explore the effect of FDA-approved antiseizure drugs in the brain connectivity patterns of severe and moderate acute brain injury patients with suppression of consciousness.
- Conditions
- Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia
- Trial name
- NCT06081283
- Testing
- Phenobarbital Sodium Injection, Levetiracetam, Lacosamide Injectable Product
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Attention Deficit Hyperactivity Disorder
Disturbed Structural Connectivity of Frontostriatal and Frontoparietal Networks in Adults With ADHD
Attention deficit/hyperactivity disorder (ADHD) is a common, impairing, childhood onset neuropsychiatric disorder with executive dysfunctions. The ADHD symptoms and executive deficits may last to adulthood.
- Trial name
- NCT02232464
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy
How Much Virtual Reality Intervention Improve the Balance of Patients With Cerebral Palsy
The purpose of this clinical study is to investigate how effective virtual reality applications are in adult cerebral palsy rehabilitation.
- Trial name
- NCT06769178
- Testing
- Virtual Reality based
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Yeditepe University
Disorders of Consciousness
Resting State fMRI in Disorders of Consciousness
Disorders of consciousness (DoC) remain a major clinical challenge in which high rates of misdiagnosis and difficult prognostication stem from limitations in the ability to access the disordered physiological processes mechanisms…
- Trial name
- NCT05463029
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Migraine, Nocebo Effects
Default Mode Network Connectivity and Nocebo Responses in Migraine: A Functional MRI Study
People with migraine sometimes experience symptoms because they expect a treatment to cause side effects. This is known as the "nocebo effect".
- Trial name
- Does not exist (NCT07720895)
- Testing
- intravenous saline infusion, Negative verbal suggestion, No intervention
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Ioanna Spanou
Stroke, Motor Disorder
Effects of Brain Network by Simultaneous Dual-mode Stimulation in Subacute Stroke Patients
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03279640
- Testing
- rTMS on ipsilesional M1, tDCS on contralesional M1
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Acupuncture
Effectiveness of YNSA Acupuncture on Brain Networks
This study investigates the effects of a new form of acupuncture (Yamamoto's New Skull Acupuncture [YNSA]) on resting-state brain networks.
- Trial name
- NCT04795024
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Premature Ejaculation, Sexual Dysfunction
Brain Networks Implicated in Lifelong Premature Ejaculation Patients
Using Brain Mapping and Cognitive ERPs, the investigatos have searched for a Brain Networks involved during Inhibitory Control in Lifelong Premature Ejaculation (LPE) participants.
- Trial name
- LPE (NCT04850703)
- Testing
- Transcranial Radom Noise Stimulation, Take Dapoxetine, Compare LPE EEG endophenotype between participants and healthy controls
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Moises Domingo
Languages
Establishing the Language Network With Independent Component Analysis of Resting State MRI
Proceed to an analysis of sensitivity and specificity results of the fMRI language network obtained in two ways: by providing a conventional language test and independent component analysis.
- Trial name
- ICA Langage (NCT02577757)
- Testing
- MRI
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cerebral Small Vessel Diseases
Effect of Hyperbaric Oxygen on Functional Connectivity in Patients With Cerebral Small Vessel Disease
Patients will have a Functional MRI before and after 10 hyperbaric Oxygen treatments.
- Trial name
- NCT02890888
- Testing
- hyperbaric oxygen treatment
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Autonomous Sensory Meridian Response, Audiobook
Effects of ASMR on the Default Mode Network
This study investigates the effects of Autonomous Sensory Meridian Response (ASMR) stimulation on resting-state brain networks. Therefore, two resting-state fMRI scans are measured in healthy adults.
- Trial name
- NCT05266508
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Brachial Plexus Neuropathies, Traumatic Brachial Plexus Lesion
Central Programming in Patients With a Bionic Hand After Traumatic Brachial Plexus Injury
Traumatic brachial plexus lesions may lead to permanent impairment of hand function despite brachial plexus surgery. In selected cases the affected forearm can be amputated and replaced by a bionic hand.
- Conditions
- Brachial Plexus Neuropathies, Traumatic Brachial Plexus Lesion, Bionic Hand Reconstruction
- Trial name
- NCT04649749
- Testing
- MRI
- Where
- Austria
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Treatment Resistant Depression
Low Field Magnetic Stimulation for Treatment Resistant Depression
This is a double-blind, randomized, sham-controlled phase II study of the effects of Low Field Magnetic Stimulation (LFMS) on brain circuitry of adults with treatment-resistant Major Depressive Disorder (MDD).
- Trial name
- NCT01944644
- Testing
- Active Low Field Magnetic Stimulation
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Weill Medical College of Cornell University
Full PRT, Partial PRT (Non Somtic)
Rewiring Chronic Pain
This study examines the effectiveness of a brief psychological intervention for chronic pain treatment, as well as the psychological and neurophysiological mechanisms associated with changes in pain intensity.
- Conditions
- Full PRT, Partial PRT (Non Somtic), Treatment as Usual
- Trial name
- NCT07724808
- Testing
- Pain Reprocessing Therapy (PRT), TAU
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Ben-Gurion University of the Negev
Hypoxia Ischemia, Cerebral, Hypoxia-Ischemia, Brain
Functional Imaging of Baby Brains
Infants are at risk of developing motor and cognitive neurodevelopmental disabilities as a sequelae to hypoxic-ischemic brain injury during the perinatal period.
- Conditions
- Hypoxia Ischemia, Cerebral, Hypoxia-Ischemia, Brain, Hypoxia Neonatal, Hypoxic-Ischemic Encephalopathy
- Trial name
- FIBB (NCT05514665)
- Testing
- Diffuse Optical Tomography
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Hamilton Health Sciences Corporation
Healthy
Trait Anxiety and Defensive Networks
to examine the association between trait and defensive network connectivity and the modulatory effect of oxytocin on it
- Trial name
- NCT02682888
- Testing
- trait anxiety scale, Oxytocin
- Where
- China
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cognitive Impairment, Dementia
Predicting MRI Abnormalities With Longitudinal Data of the Whitehall II Substudy
Follow-up study within the Whitehall II study, selecting 800 participants for further neuropsychological, clinical and imaging (MRI) examinations to examine brain structure and function in relation to age-related diseases and the…
- Conditions
- Cognitive Impairment, Dementia, Affective Disorders
- Trial name
- NCT03335696
- Where
- United Kingdom
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Oxford