Clinical trials: Restless Leg Syndrome
Restless Legs Syndrome
Transdermal Lisuride: a Trial for the Treatment of Patients With Restless Legs Syndrome (RLS)
The objective of this trial is to compare an individually optimized dose of the lisuride TTS patch against placebo and against an individually optimized dose of oral ropinirole (active- and placebo-controlled design) in…
- Trial name
- NCT00367822
- Testing
- Lisuride, Ropinirole
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Axxonis Pharma AG
Multiple Sclerosis
Aerobic Exercise in Persons With Multiple Sclerosis With Restless Legs Syndrome
In this studly, the effects of an 12-week aerobic exercise training in persons with multiple sclerosis with restless legs syndrome will be investigated.
- Trial name
- NCT05402956
- Testing
- Aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Dokuz Eylul University
Restless Legs Syndrome, Insomnia
Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia
The investigators aim to determine the effect of suvorexant on actigraphically-derived total sleep time in patients with effectively treated restless legs syndrome with persistent insomnia in a two-arm, double-blind, randomized…
- Conditions
- Restless Legs Syndrome, Insomnia, Sleep Disorder
- Trial name
- NCT04706091
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Massachusetts General Hospital
Restless Legs Syndrome
A Study to Determine the Efficacy and Safety of Cabergoline for the Treatment of Patients With RLS
The purpose of this study is to evaluate the efficacy and safety of cabergoline compared with levodopa in the treatment of patients with RLS.
- Trial name
- NCT00625547
- Testing
- cabergoline, levodopa
- Where
- 50 sites in Austria, Germany and 2 more
- Volunteers
- 361 people
- Sponsor
- Pfizer
Restless Leg Disorder, Restless Leg Syndrome (RLS)
Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome
The goal of this study is to evaluate whether peroneal electrical nerve stimulation (PNS) using the TOMAC™ device is a feasible, acceptable, and safe non-pharmacologic intervention for managing Restless Legs Syndrome (RLS) during…
- Conditions
- Restless Leg Disorder, Restless Leg Syndrome (RLS), Pregnancy, Sleep Disorder (Disorder)
- Trial name
- PENS-P (NCT07144631)
- Testing
- Peroneal Nerve Stimulation (PNS) Device
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Rhode Island Hospital
Restless Legs Syndrome (RLS)
Randomized, Placebo-controlled Trial of Ferric Carboxymaltose in RLS Patients With Iron-deficiency Anemia
Treatment Phase I and II Primary Objective: To evaluate the efficacy and safety of FCM (750 mg dose x 2) for treatment of Restless Legs Syndrome (RLS) in patients with iron-deficiency anemia (IDA).
- Trial name
- NCT02826681
- Testing
- Injectafer® (Ferric Carboxymaltose - FCM)
- Where
- 8 sites in United States
- Volunteers
- 70 people
- Sponsor
- American Regent, Inc.
Hemodialysis Complication
PMR Versus MLD on RLS and Sleep Quality in Hemodialysis Patients
Progressive muscle relaxation versus manual lymphatic drainage on restless leg syndrome and sleep quality in hemodialysis patients
- Trial name
- NCT06481800
- Testing
- Progressive muscle relaxation (PMR), cnotrol group, Manual lymphatic drainage (MLD)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- MTI University
Restless Legs Syndrome
Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration)
This is a multicenter, placebo controlled, parallel group, double-blind, randomized comparison study to evaluate the efficacy and safety of ropinirole IR tablets orally administered for 12 weeks in patients with symptomatic…
- Trial name
- NCT00996944
- Testing
- Ropinirole immediate release (IR)
- Where
- 19 sites in Japan
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Stroke, Ischemic Attack, Transient
Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke
The aim of the investigators was to determine whether the immediate management of any detected sleep disorders can improve outcomes in patients who have had a transient ischemic attack (TIA) or minor stroke.
- Conditions
- Stroke, Ischemic Attack, Transient, Sleep Disorders, Sleep Apnea Syndromes
- Trial name
- SMARTIES (NCT01528462)
- Testing
- Expedited Treatment of Sleep Disorders
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- Sunnybrook Health Sciences Centre
Haemodialysis-induced Symptom
Sleep Quality and Related Factors in Hemodialysis Patients
Sleep quality is an important predictor of healthy status,quality of life and life span. Sleeping problems affect 50%~80% in hemodialysis patients.
- Trial name
- NCT01327560
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Medical University WanFang Hospital