Clinical trials: Restoration
Mid-face Volume Deficit
Efficacy and Safety of Rejuviel V in the Correction of Midface Volume Deficit
The purpose is to evaluate the efficacy and confirm the safety of Rejeunesse Contour® with Lidocaine compared to Juvederm® Voluma® with Lidocaine for the temporary improvement of mid-face volume (including the cheekbone area, the…
- Trial name
- NCT07162610
- Testing
- Rejuviel V® with lidocaine, JUVEDERM® VOLUMA® with lidocaine
- Where
- South Korea
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- PharmaResearch Co.,Ltd
Dental Restoration, Caries
Cold Plasma for Dental Restoration and Caries Prevention
The main objective of this entire research project is to develop a miniature atmospheric cold plasma brush (m-ACPB) for dental clinical applications.
- Trial name
- NCT01529606
- Testing
- Composite restoration and tooth cleaning, Plasma treatment
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Nanova, Inc
Sensitivity, Tooth
Clinical Evaluation of OBU When Used for Indirect Dental Restorations
The objective of this study is to evaluate the clinical safety and performance of Optibond Universal (OBU), a single component universal dental adhesive intended for indirect dental restorations according to manufacturer's…
- Trial name
- NCT06002880
- Testing
- Optibond Universal
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kerr Corporation
Pain, Stress
6-Month Outcomes of PEMF to Nucleotide Sources Revealing Cell Sensory Experience in Pain Relief, Stress Relief and Anti Ageing Restoration
Background: The hz Clinic registry is a programme made of five scheduled cohorts designed to include participants dealing with Immunity compromise, Pain, Ageing and Stress (general and pandemic anxieties) who are to be followed…
- Conditions
- Pain, Stress, Ageing Signs, Immunity Compromise
- Trial name
- PEMF (NCT04461470)
- Testing
- epigenetic longitudinal waves
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- hz Clinic
Erectile Dysfunction
IT Matters: The Erectile Restoration Registry
The objective of the It MATTERS registry is to collect Real-World Data (RWD) to monitor the safe and effective use of commercially available Boston Scientific Corporation (BSC) penile prostheses
- Trial name
- NCT04200937
- Testing
- Tactra Malleable, Spectra™ Concealable Penile Prothesis, AMS Ambicor™ Inflatable Penile Prosthesis
- Where
- 25 sites in United States, China and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Implant, Healthy
A 5-year Clinical Evaluation Study on NobelReplace Conical Connection Implants
A new Nobel Biocare implant, NobelReplace Conical Connection (NR CC) has been developed. The implant is a two piece design to allow both one- and two- stage surgical procedures.
- Trial name
- NCT02175550
- Testing
- NR CC
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Rehabilitation of Speech and Language Disorders, Speech Disorders
MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments
This study will evaluate the ability of MyoVoice to replace natural speech. Referred to generally as an Augmentative and Alternative Communication (AAC) device, MyoVoice uses electrical signals recorded non-invasively from speech…
- Conditions
- Rehabilitation of Speech and Language Disorders, Speech Disorders, Speech, Alaryngeal, Communication Aids for Disabled
- Trial name
- NCT04762043
- Testing
- Experimental System: MyoVoice, Reference System: Electrolarynx
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Altec Inc.
Aging, Healthy
The Evaluation of Efficacy and Safety of Stylage® XL Lidocaïne for the Restoration and/or Augmentation of Facial Volume
Stylage® XL Lidocaïne is a CE-marketed hyaluronic acid gel indicated for the restoration or augmentation of facial volume by injection into the deep dermis or subcutaneously.
- Trial name
- BeautyVolume (NCT04166292)
- Testing
- Stylage® XL Lidocaïne
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Dental Prosthesis Failure, Dental Prosthesis Complication
Clinical Study of a 3D Shaded Zirconia for Chairside CAD/CAM Restorations
This investigation will be a prospective, longitudinal clinical trial to study the clinical performance of a new monolithic, 3D shaded zirconia material for computer assisted design and computer assisted machining for chairside…
- Trial name
- NCT06713577
- Testing
- CEREC Cercon 4D
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Dentsply Sirona Implants and Consumables
Dental Caries
Comparative Study of Experimental Dental Adhesive With and Without Phosphoric Acid Pretreatment
The intent of this study is to evaluate the clinical performance of an experimental dental bonding agent for use with dental restorative composites with and without pretreatment of the tooth dentin and enamel using phosphoric…
- Trial name
- NCT02071953
- Testing
- Experimental adhesive w/out phosphoric acid in post. rest., Experimental adhesive with phosphoric acid in post. rest.
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Oral Surgical Procedures
Retrospective Observational Study of Implant-supported Restorations With Dental Implants.
This retrospective study aims to value the bone loss and the success and survival of the dental implants produced by additive manufacturing installed in an area grafted with Plenum® Osshp (synthetic bone graft).
- Trial name
- NCT06154057
- Testing
- Dental Implants installed in an grafted area (sinus lifting), Dental Implants installed in an grafted area (ridge augmentation), Dental Implants installed in an grafted area (extraction sites)
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- M3 Health
Dental Caries
Clinical Performance of Incremental and Bulk Fill Composites in Class II Restorations
This study will examine the clinical performance of Class II restorations over a three year period with 3 composite resins - a conventional composite resin, a flowable composite resin and a bulk placed and cured composite resin.
- Trial name
- NCT02889835
- Testing
- Supreme Universal Restorative, Supreme Flowable Restorative, Bulk Fill Flowable Restorative
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Vulvar Atrophy
Evaluation of the Efficacy and Safety of Hyaluronic Acid Injection in Labia Majora for Volume Restoration
DESIRIAL® PLUS is a CE-marketed hyaluronic acid (since 2011) whose registered indications are moderate hypotrophy, severe hypotrophy or atrophy of the vulvar Labia Majora by subcutaneous injections.
- Trial name
- ESOLANE (NCT04147689)
- Testing
- DESIRIAL® PLUS
- Where
- 9 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Healthy Volunteers With Severely Resorbed Jaws in Need of an Implant Supported Restoration
Extra Short Implants Brånemark System® RP Ø4.5x4.5 mm Implants
An extra short, 2-piece implant with a Brånemark hexagon interface was developed with a bone anchoring length of only 4.5 mm, for subjects with severely resorbed jaws.
- Trial name
- NCT02178891
- Testing
- extra short implant
- Where
- 2 sites in Germany
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Women Who Have Had Breast Enhancement With Macrolane VRF
Macrolane Retrospective Study
This is a retrospective, multicenter chart review of medical records on the use of Macrolane for female breast enhancement. The primary objective is to evaluate the safety profile of Macrolane Volume Restoration Factor 20 and…
- Trial name
- NCT01223963
- Where
- 4 sites in Sweden
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Skin Aging
Evaluation of the Safety and Efficacy of Profhilo® Structura
Profhilo® Structura is composed of a buffered saline solution of high molecular weight (H-HA) and low molecular weight (L-HA) hyaluronic acid.
- Trial name
- NCT06719154
- Testing
- Profhilo Structura
- Where
- 3 sites in France, Poland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Posterior Bridge Restoration
NobelProceraTM Bridge Shaded Zirconia
Industrial centrally produced 3- or 4-unit bridges of shaded yttrium-oxide partially-stabilized (Y-TZP) zirconia (NobelProceraTM Shaded Zirconia) in combination with a veneering ceramic material will show sufficient CDA ratings…
- Trial name
- NCT02197312
- Testing
- NobelProcera Bridge Shaded Zirconia
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Volume Restoration and Shaping of the Buttocks
A Study to Evaluate Efficacy and Safety of Macrolane VRF30 for Volume Restoration and Contouring of the Buttocks
The purpose of the study is to evaluate the efficacy and safety of Macrolane for volume restoration and shaping of the buttocks.
- Trial name
- NCT01331408
- Testing
- Macrolane VRF30
- Where
- 4 sites in Belgium, Spain and 1 more
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Dental Implants, Edentulous
Tissue Level vs Bone Level Implants for Plural Restorations : a Multicentre Randomised Controlled Trial
Anthogyr Axiom Tissue-Level implants and corresponding Multi-Unit abutments recently enriched the available product range for dental surgeons.
- Trial name
- IBERICA (NCT05223387)
- Testing
- Axiom TL REG, Axiom BL REG
- Where
- 3 sites in Portugal, Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anthogyr
Females Recently Treated With Macrolane VRF in the Breasts
Macrolane Prospective Survey
The study objective is to evaluate the long term safety when Macrolane Volume Restoration Factor is used in female breasts in clinical practice.
- Trial name
- NCT01223066
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Galderma R&D