Clinical trials: Restrictive Lung Disease
Nephrectomy, Lung Diseases
Thoracic Spinal Versus Epidural Anesthesia for Nephrectomy in Obstructive/Restrictive Lung Disease Patients
Patients with respiratory disease have an increased risk of developing complications perioperatively. The use of regional anesthesia decreases this risk with better postoperative outcome.
- Conditions
- Nephrectomy, Lung Diseases, Anesthesia
- Trial name
- NCT03324490
- Testing
- Thoracic Spinal Anesthesia, Thoracic Epidural Anesthesia, Bupivacaine 0.5% (hyperbaric)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Nazmy Edward Seif
Parkinson Disease, Camptocormia
The Effect of Spinal Mobilization on Respiratory Parameters in Parkinson's Disease Patients
Parkinson's patients suffer from respiratory distress for different reasons. It is thought that physiotherapy methods that have an indirect effect on the diaphragm can improve respiratory functions.
- Conditions
- Parkinson Disease, Camptocormia, Restrictive Lung Disease
- Trial name
- NCT04941326
- Testing
- Diaphragmatic stimulation treatment with PNF techniques, Costal mobilization, Breathing exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Abant Izzet Baysal University
Asthma, Chronic Obstructive Pulmonary Disease (COPD), or Chronic Lung Disease (E.G., Chronic Bronchitis and Restrictive Lung Diseases Such as Asbestosis), The Effect of Yoga, Paranayama Yoga Practice on Respiratory Diseases
EFFECT OF PRANAYAMA YOGA ON COPD
The aim of the study In this study, pranayama yoga practices are the sub-dimensions of respiratory parameters, symptom and disease affection level, psychosocial adjustment and psychosocial adjustment in individuals with COPD.
- Trial name
- COPD (NCT06022627)
- Testing
- Pranayama Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Lung Transplant Failure and Rejection, CLAD, Bronchiolitis Obliterans
Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLAD
This study is for people who have had a lung transplant and developed a condition called chronic lung allograft dysfunction (CLAD), which is a type of chronic rejection.
- Conditions
- Lung Transplant Failure and Rejection, CLAD, Bronchiolitis Obliterans, Extracorporeal Photopheresis
- Trial name
- NCT07434869
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Brian Keller
Chronic Obstructive Pulmonary Disease, Bronchial Asthma
Influence of Bag Volume Variation on the Reproducibility of Inert Gas Rebreathing
Non-invasive inert gas rebreathing (IGR) based on the Fick Principle showed promising results in the determination of pulmonary blood flow (PBF).
- Conditions
- Chronic Obstructive Pulmonary Disease, Bronchial Asthma, Restrictive Pulmonary Disease
- Trial name
- NCT01762917
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Restrictive Lung Disease
Thoracic Mobilization for Restrictive Lung Disease
This study aims to investigate the immediate effects of thoracic mobilization techniques on cough capacity, dyspnea, and pulmonary function in patients with restrictive lung disease.
- Trial name
- NCT07012733
- Testing
- Thoracic mobilization, conventional therapy
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Chungnam National University Sejong Hospital
Covid19 Pneumonia, Chronic Thromboembolic Pulmonary Hypertension
COVID-19 Pneumonia: Pulmonary Physiology, Health-related Quality of Life and Benefit of a Rehabilitation Program
The pathophysiological processes involved in COVID-19 pneumonia are not fully understood. Specific alterations of the airways, lung parenchyma and pulmonary vascular tree could explain a severe ventilation/perfusion heterogeneity…
- Conditions
- Covid19 Pneumonia, Chronic Thromboembolic Pulmonary Hypertension, Myopathy, Restrictive Lung Disease
- Trial name
- COVISQAR (NCT04881214)
- Testing
- Pulmonary rehabilitation
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Geneva
COPD, Lung Function
Lung Function Decline and Disease Risk From Young Adulthood to Middle Age
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States, but markers that predict risk of developing disease outside of cigarette smoking have not been identified.
- Conditions
- COPD, Lung Function, Heart - Lung Interaction, Restrictive Lung Disease
- Trial name
- CARDIA Lung (NCT02245178)
- Testing
- Lung spirometry, CT scan analysis
- Volunteers
- 3,193 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Respiratory Distress Syndrome, Newborn
Fluid Restriction in Respiratory Distress of the Newborn
The object of this study is to determine the best way to care for infants with respiratory distress. The investigators are testing a method of feeding fluids to infants with respiratory distress in amounts similar to what healthy…
- Trial name
- NCT03120585
- Testing
- Fluid Management Intervention
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of Oklahoma
Complication, Postoperative
Perioperative Fluid Management: Goal-directed Versus Restrictive Strategy
There is no ideal "cookbook recipe" for fluid prescription that would fit every surgical patient. In this study, the investigators working hypothesis is that the adoption of an integrative algorithm for perioperative fluid and…
- Trial name
- NCT02625701
- Testing
- Goal-directed therapy, Restrictive fluid therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Geneva
Pulmonary Atelectasis, Postoperative
Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery
the aim of this prospective randomized blinded clinical study will be to assess the ultrasound evaluation of different preventive measures of post operative lung atelectasis in abdominal surgeries; these measures include…
- Trial name
- LUS/PEEP/RM (NCT06654778)
- Testing
- PEEP, PEEP/RM, PEEP/RM/RF
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Restrictive Pulmonary Disorders, Non Invasive Ventilation
Impact of Non Invasive Ventilation on Quality of Sleep
Quality of sleep is profoundly affected in patients with hypercapnic respiratory failure and restrictive disorders, with a decrease in rapid eye movement (REM) and slow wave sleep, and an increase in sleep fragmentation.
- Trial name
- NCT00991536
- Volunteers
- 95 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Ventilator Associated Pneumonia, Critical Care
Delayed Antibiotic Therapy in Non-severe Ventilator Acquired Pneumonia (VAP)
This retro-prospective monocentric observational study compare the impact of the implementation of a restrictive (delayed) versus aggressive (immediate) antibiotic strategy for Ventilator Acquired Pneumonia suspicion without…
- Conditions
- Ventilator Associated Pneumonia, Critical Care, Antibiotic Therapy
- Trial name
- DELAVAP (NCT05205525)
- Testing
- Restrictive antibiotic strategy, Aggressive antibiotic strategy
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Nantes University Hospital
Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD)
Improving Clinician Communication Skills (ICCS)
This research study is a randomized trial to evaluate a training program that is designed to improve the communication skills of clinicians.
- Conditions
- Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD), Restrictive Lung Disease, Congestive Heart Failure
- Trial name
- ICCS (NCT00687349)
- Testing
- Training Program Intervention
- Where
- 4 sites in United States
- Volunteers
- 6,086 people
- Sponsor
- University of Washington
Hypoventilation Syndrome, Chronic Obstructive Pulmonary Disease
The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation
Patients suffering chronic hypercapnic respiratory insufficiency (e.g. in chronic obstructive pulmonary disease, obesity hypoventilation syndrome) benefit from home mechanical ventilation.
- Conditions
- Hypoventilation Syndrome, Chronic Obstructive Pulmonary Disease, Obesity Hypoventilation Syndrome, Restrictive Lung Disease
- Trial name
- NCT03506906
- Testing
- Sleep studies under noninvasive ventilation therapy, Routine tests
- Where
- Germany
- Volunteers
- 105 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Obstructive Pulmonary Disease, Cardiomyopathies
Cardio-pulmonary Rehabilitation and Sleep Quality
In this prospective cohort study the investigators aim to evaluate the effect of pulmonary rehabilitation on sleep quality. Disturbed sleep is associated with, frequent exacerbations, increase in the severity of disease and…
- Conditions
- Obstructive Pulmonary Disease, Cardiomyopathies, Heart Failure, Restrictive Lung Disease
- Trial name
- NCT04668599
- Testing
- Cardiopulmonary rehabilitation
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- MetroHealth Medical Center
Esophageal Atresia, Oesophageal Atresia
Evaluation of the Respiratory Impact After Conventional or Minimally Invasive Esophageal Atresia Surgery
Right thoracotomy, conventional approach to esophageal atresia repair, leads to up to 60% radiological chest wall sequelae anomalies. The impact of these anomalies on the patient's respiratory function remains unknown.
- Conditions
- Esophageal Atresia, Oesophageal Atresia, Restrictive Lung Disease, Chest Wall Anomaly
- Trial name
- RestriMIS (NCT04136795)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Angers
Study the Effectiveness of Combined Manual Therapy and Pulmonary Exercises on Ventilatory Function in Patients with Restrictive Lung Diseases
Effectiveness of Combined Manual Therapy and Pulmonary Exercises on Ventilatory Function in Patients with Restrictive Lung Diseases
This research investigates the effect of selective manual therapy techniques on chest expansion, pulmonary function (FVC, FEV1, and FEV1/FVC ratio), and functional capacity, in restrictive lung disease patients.
- Trial name
- NCT06681701
- Testing
- Combined Manual Therapy and Pulmonary Exercises
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- South Valley University
Lung Diseases, Obstructive, Lung Diseases
Determination of Posture in Patients With Restrictive and Obstructive Lung Disease
The aim of this study is to determine posture and posture related factors in patients with restrictive and obstructive lung disease.
- Conditions
- Lung Diseases, Obstructive, Lung Diseases, Postural; Defect
- Trial name
- NCT06306482
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Acute Heart Failure, Pulmonary Congestion
Oxygen Targets in Acute Heart Failure With Pulmonary Congestion
REDOX-AHF compared two oxygen saturation targets in adults admitted with acute heart failure and clinical or radiological signs of congestion.
- Conditions
- Acute Heart Failure, Pulmonary Congestion, Hypoxemia
- Trial name
- REDOX-AHF (NCT05613218)
- Testing
- Oxygen
- Where
- 2 sites in Denmark
- Volunteers
- 135 people
- Sponsor
- Copenhagen University Hospital, Hvidovre