Clinical trials: Restrictive Lung Disease
Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD)
Improving Clinician Communication Skills (ICCS)
This research study is a randomized trial to evaluate a training program that is designed to improve the communication skills of clinicians.
- Conditions
- Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD), Restrictive Lung Disease, Congestive Heart Failure
- Trial name
- ICCS (NCT00687349)
- Testing
- Training Program Intervention
- Where
- 4 sites in United States
- Volunteers
- 6,086 people
- Sponsor
- University of Washington
Obstructive Pulmonary Disease, Cardiomyopathies
Cardio-pulmonary Rehabilitation and Sleep Quality
In this prospective cohort study the investigators aim to evaluate the effect of pulmonary rehabilitation on sleep quality. Disturbed sleep is associated with, frequent exacerbations, increase in the severity of disease and…
- Conditions
- Obstructive Pulmonary Disease, Cardiomyopathies, Heart Failure, Restrictive Lung Disease
- Trial name
- NCT04668599
- Testing
- Cardiopulmonary rehabilitation
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- MetroHealth Medical Center
Restrictive Lung Diseases
Effects of Inspiratory Muscle Training and Positive Expiratory Pressure on Mechanically Ventilated Restrictive Lung Disease Patients
Restrictive lung diseases (RLD) represent a significant cause of morbidity, often necessitating intensive interventions such as mechanical ventilation due to diminished lung compliance (LC) and reduced total lung capacity (TLC).
- Trial name
- NCT07867730
- Testing
- Inspiratory muscle training, Conventional Chest Physical Therapy
- Where
- 3 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Lung Transplant, Post Lung Transplantation
CLAD Phenotype Specific Risk Factors and Mechanisms
While many patients experience benefits from transplant, complications such as infections and lung rejection may affect long term survival and quality of life.
- Trial name
- NCT02631720
- Testing
- Blood Draw, Bronchoscopy
- Where
- 5 sites in United States, Canada
- Volunteers
- 884 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections
Ontario ICU Clinical Best Practices Demonstration Project
The pragmatic issue at hand how to get physicians and nurses to use best practices… and how to measure consequences of their implementation.
- Conditions
- Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections, Pressure Ulcer Prophylaxis, DVT Prophylaxis
- Trial name
- NCT00332982
- Testing
- Focused knowledge translation strategies
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Pulmonary Disease, Chronic Respiratory Failure
Home Mechanical Ventilation Effectiveness and Air Leaks
Non invasive ventilation (NIV) usually presents air leaks that may determine the result of this treatment. The clinical usefulness of analyzing (and quantifying) these leaks during the adaptation period to NIV has not been…
- Conditions
- Pulmonary Disease, Chronic Respiratory Failure, COPD
- Trial name
- NCT01090986
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Complication, Postoperative
Perioperative Fluid Management: Goal-directed Versus Restrictive Strategy
There is no ideal "cookbook recipe" for fluid prescription that would fit every surgical patient. In this study, the investigators working hypothesis is that the adoption of an integrative algorithm for perioperative fluid and…
- Trial name
- NCT02625701
- Testing
- Goal-directed therapy, Restrictive fluid therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Geneva
Hermansky-Pudlak Syndrome (HPS), Pulmonary Fibrosis
Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak Syndrome
This study will examine whether five drugs (pravastatin, Losartan, Zileuton, N-acetylcysteine and erythromycin) used together can slow the course of pulmonary fibrosis (scarring of the lung tissue) in patients with…
- Conditions
- Hermansky-Pudlak Syndrome (HPS), Pulmonary Fibrosis, Oculocutaneous Albinism, Platelet Storage Pool Deficiency
- Trial name
- NCT00467831
- Testing
- Losartan, Zileuton, N-Acetylcysteine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Asthma, Chronic Obstructive Pulmonary Disease (COPD), or Chronic Lung Disease (E.G., Chronic Bronchitis and Restrictive Lung Diseases Such as Asbestosis), The Effect of Yoga, Paranayama Yoga Practice on Respiratory Diseases
EFFECT OF PRANAYAMA YOGA ON COPD
The aim of the study In this study, pranayama yoga practices are the sub-dimensions of respiratory parameters, symptom and disease affection level, psychosocial adjustment and psychosocial adjustment in individuals with COPD.
- Trial name
- COPD (NCT06022627)
- Testing
- Pranayama Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Ventilator Associated Pneumonia, Critical Care
Delayed Antibiotic Therapy in Non-severe Ventilator Acquired Pneumonia (VAP)
This retro-prospective monocentric observational study compare the impact of the implementation of a restrictive (delayed) versus aggressive (immediate) antibiotic strategy for Ventilator Acquired Pneumonia suspicion without…
- Conditions
- Ventilator Associated Pneumonia, Critical Care, Antibiotic Therapy
- Trial name
- DELAVAP (NCT05205525)
- Testing
- Restrictive antibiotic strategy, Aggressive antibiotic strategy
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Nantes University Hospital
Cerebral Palsy
Study Assessing High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations
To asssess efficacy of airway clearance provided by Vest therapy (HFCWO) in the reduction of respiratory exacerbations requiring hospitalization or antibiotic utilization in patients with muscle weakness and restrictive lung…
- Trial name
- NCT00739310
- Testing
- Vest Treatment (high frequency chest wall oscillation)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Hill-Rom
Hypertension, Pulmonary Arterial, Out-Of-Hospital Cardiac Arrest
REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)
Background: For patients with out-of-hospital cardiac arrest (OHCA) at the intensive care unit (ICU), oxygen therapy plays an important role in post resuscitation care.
- Conditions
- Hypertension, Pulmonary Arterial, Out-Of-Hospital Cardiac Arrest, Intensive Care Unit, Oxygen Therapy
- Trial name
- RELIEPH (NCT05029167)
- Testing
- Restrictive PaO2, Low normal MAP, Liberal PaO2
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- University of Southern Denmark