Clinical trials: Resuscitations
Burns
Fluid Resuscitation in Patients Suffering From Burns Injury
This clinical study compares two fluid resuscitation treatments in patients suffering from burns injury. The treatments are Volulyte® and Human Serum Albumin (HSA) which will be administered as infusion solutions.
- Trial name
- NCT01689506
- Testing
- Volulyte, Human Serum Albumin
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Fresenius Kabi
Sudden Cardiac Death, Ventricular Fibrillation
LifeVest Post-CABG Registry
This is a multi-center prospective registry of patients with an ejection fraction (EF) ≤ 35% following coronary artery bypass graft (CABG) surgery in order to test the hypothesis that wearable defibrillators (WD) will decrease…
- Conditions
- Sudden Cardiac Death, Ventricular Fibrillation, Ventricular Tachycardia, Ventricular Dysfunction
- Trial name
- NCT01448005
- Testing
- wearable defibrillator (LifeVest)
- Where
- 5 sites in United States
- Volunteers
- 69 people
- Sponsor
- Zoll Medical Corporation
Dengue Shock Syndrome
Effect of Hypertonic Sodium Lactate on sVCAM-1 Level as Surrogate Marker of Endothelial Capillary Leakage in Pediatric Dengue Shock Syndrome Patients (DSS)
Dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) are among the leading causes of pediatric hospitalization in Asia.Mortality rates range from 1% at centres experienced in fluid resuscitation, to upto 44% in…
- Trial name
- NCT00966628
- Testing
- Hypertonic sodium lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Septic Shock
Early Albumin Resuscitation During Septic Shock
Objective: To determine whether the early administration of albumin as an expander and antioxidant would improve survival on the 28th day for septic shock patients.
- Trial name
- NCT00327704
- Testing
- albumin, saline
- Where
- France
- Volunteers
- 794 people
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Septic Shock
Effect of Early Administration of Albumin 20% Versus Crystalloid
Sepsis and septic shock are global health problems, leading to a high mortality rate. They are often associated with extremely low blood pressure and multiple organ dysfunctions, which are the main causes of death in critically…
- Trial name
- NCT06370078
- Testing
- Albumin Human
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Egymedicalpedia
Heart Arrest, Death, Sudden, Cardiac
ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest
The purpose of this study is to determine whether performing active compression decompression cardiopulmonary resuscitation (ACD-CPR) with an impedance threshold device (ITD) compared to conventional standard cardiopulmonary…
- Conditions
- Heart Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, Cardiac Arrest
- Trial name
- ResQ (NCT00189423)
- Testing
- Use of an impedance threshold device (ITD) during the performance of active compression decompression CPR (ACD-CPR), Standard cardiopulmonary resuscitation (S-CPR)
- Where
- 7 sites in United States
- Volunteers
- 1,653 people
- Sponsor
- Advanced Circulatory Systems
Acute Respiratory Distress Syndrome (ARDS)
Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in Patients With ARDS
Acute respiratory distress syndrome (ARDS) is a life-threatening condition with a diffuse, inflammatory form of lung injury, causing pulmonary infiltration and respiratory failure leading to poor oxygenation.
- Trial name
- NCT05241067
- Testing
- Normal Saline, Centhaquine
- Volunteers
- 80 people
- Sponsor
- Pharmazz, Inc.
Cardiac Arrest (CA)
The VENTOR Clinical Study
To evaluate the initial safety and effectiveness of the Ventor Airway System in providing short-term ventilation support in non-breathing subjects during cardiopulmonary resuscitation (CPR) and respiratory arrests.
- Trial name
- VENTOR (NCT06759389)
- Testing
- Resuscitation (Ventor)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- CoLabs Medical
Heart Transplant
Donor After Circulatory Death Heart CAP Trial
The Portable Organ Care System (OCS™) Heart for Resuscitating, Preserving and Assessing Hearts Donated after Circulatory Death Continued Access Protocol (OCS DCD Heart CAP)
- Trial name
- NCT04615182
- Testing
- Transplant
- Where
- 25 sites in United States
- Volunteers
- 90 people
- Sponsor
- TransMedics
Healthy
The Safety of Autologous Lyophilized Plasma Versus Fresh Frozen Plasma in Healthy Volunteers
A single-site, single-blind study of ascending doses of Lyophilized Plasma in normal healthy volunteers.
- Trial name
- NCT00968487
- Testing
- Lyophilized Plasma, Fresh Frozen Plasma
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- HemCon Medical Technologies, Inc
Resuscitation, Cardiopulmonary
Effect of Early High-dose Epoetin Alfa During Cardiac Arrest (Pilot Study)
The purpose of this study is to test the possible neuroprotective effect of early high dose erythropoietin alpha after out of hospital cardiac arrest (OHCA).
- Conditions
- Resuscitation, Cardiopulmonary, Cardiac Arrest
- Trial name
- NCT00719498
- Testing
- Epo-alpha
- Volunteers
- 20 people
- Sponsor
- Janssen Cilag S.A.S.
Heart Transplant
Donors After Circulatory Death Heart Trial
To evaluate the effectiveness of the OCS Heart System to resuscitate, preserve and assess hearts donated after circulatory death for transplantation to increase the pool of donor hearts available for transplantation.
- Trial name
- NCT03831048
- Testing
- OCS Heart System, Cold Storage
- Where
- 25 sites in United States
- Volunteers
- 180 people
- Sponsor
- TransMedics
Cardiac Arrest
Cardiopulmonary Resuscitation in Cases of Sudden Cardiac Arrest
Determination the success rate of CPR on adults in Emergency room and predicting the factors that makes CPR is successful.
- Trial name
- NCT05716789
- Testing
- CPR
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Egymedicalpedia
Shock
Rapid Treatment of Shock Without Trauma
Evaluate the implementation of a standardized mobile resuscitation model to manage SWOT within a large acute care hospital setting.
- Trial name
- SWOT (NCT05073354)
- Testing
- Full SWOT Model
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Zoll Medical Corporation
Cardiac Arrest
The Haemodynamic Effects of Mechanical Standard and Active Chest Compression-decompression During Out-of-hospital CPR
The aim of this randomized out-of-hospital cardiopulmonary resuscitation study is to investigate haemodynamics generated by the standard mechanical external chest compression device (LUCAS™ 2) compared to a new version generating…
- Trial name
- NCT02479152
- Testing
- LUCAS2 AD
- Where
- Norway
- Volunteers
- 126 people
- Sponsor
- Physio-Control
Low Cardiac Output
Efficacy, Safety of Hypertonic Lactate Soln. as Fluid Resuscitation Compared With Ringer's Lactate in Post-CABG Pats
Prospective, randomized, open-label study to assess the efficacy and safety of hypertonic lactate solution, compared to Ringer's Lactate as fluid resuscitation to maintain hemodynamic stability in post-coronary artery bypass…
- Trial name
- NCT00529490
- Testing
- Hypertonic lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 230 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Heart Arrest
Thrombolysis Using Tenecteplase (Metalyse®) in Cardiac Arrest - The TROICA Trial
The general aim of this study is to compare the efficacy and safety of tenecteplase to standard treatment during cardiopulmonary resuscitation in patients suffering from out-of-hospital cardiac arrest.
- Trial name
- NCT00157261
- Testing
- tenecteplase
- Where
- 68 sites in Austria, Belgium and 7 more
- Volunteers
- 1,050 people
- Sponsor
- Boehringer Ingelheim
Hypovolemic Shock
A Study to Assess the Safety and Efficacy of Centhaquine in Hypovolemic Shock Patients
This is a prospective, multi-centric, open-labeled, phase-IV clinical study to evaluate the safety and efficacy of centhaquine citrate (LYFAQUIN™), a first-in-class drug for treating hypovolemic shock, a life-threatening…
- Trial name
- NCT05956418
- Testing
- Centhaquine
- Where
- 17 sites in India
- Volunteers
- 400 people
- Sponsor
- Pharmazz, Inc.
Cardiac Arrest
Pre-ROSC Intra-Nasal Cooling Effectiveness
The purpose of the study was to demonstrate the safety and feasibility of early intranasal cooling prior to return of spontaneous circulation (ROSC) in the emergency medical services (EMS) environment.
- Trial name
- PRINCE (NCT00808236)
- Testing
- RhinoChill, Control
- Where
- 15 sites in Belgium, Czechia and 3 more
- Volunteers
- 200 people
- Sponsor
- BeneChill, Inc
Cardiac Arrest, Sudden Cardiac Death
Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest
More than 300,000 Americans experience out-of-hospital cardiac arrest annually, with overall survival rates averaging less than 5%.
- Trial name
- NCT01325870
- Testing
- ACD-CPR, ITPR, S-CPR
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Advanced Circulatory Systems