Clinical trials: Resuscitations
Blood Pressure
Intraosseous Pressure Monitoring in Intensive Care Unit Patients
In emergency situations, access to the venous system is essential in order to administer fluids and medication and to monitor patients.
- Trial name
- NCT02059928
- Testing
- Intraosseous Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- HealthPartners Institute
Birth Asphyxia, Neonatal Resuscitation
The Baby-Saver Kit: Clinical Testing of a Device for Neonatal Resuscitation With Intact Cord in Uganda
To examine the usability, safety and acceptability of the BabySaver kit: a novel device for neonatal resuscitation in a low-income region in Africa
- Conditions
- Birth Asphyxia, Neonatal Resuscitation, Maternal Distress
- Trial name
- BabySaver (NCT03885492)
- Where
- Uganda
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Sanyu Africa Research Institute
Fluid Loss, Symptom Complex, Triple
Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation
Administration of intravascular (IV) fluid is the most common emergency department (ED) procedure. IV fluids are integral to increasing effective blood volume and ensuring organ perfusion in patients with volume depletion and…
- Conditions
- Fluid Loss, Symptom Complex, Triple, Emergencies
- Trial name
- NCT03133767
- Testing
- Lactated Ringer Solution, Normal Saline 0.9% Infusion Solution Bag
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Nicholas M Mohr
Cardiac Arrest, Cardiopulmonary Resuscitation
Circulation Improving Resuscitation Care (CIRC)
During resuscitation of out of hospital cardiac arrest patients the use of a mechanical chest compression device Autopulse will improve survival compared to manual compressions.
- Trial name
- CIRC (NCT00597207)
- Testing
- AutoPulse, Manual
- Where
- 5 sites in United States, Austria and 1 more
- Volunteers
- 4,231 people
- Sponsor
- Zoll Medical Corporation
Out-of-Hospital Cardiac Arrest, Blood Pressure
Blood Pressure and OXygenation Targets After OHCA
This study compares two blood pressure targets and two oxygenation targets in the post-resuscitation care of comatose out-of-hospital cardiac arrets patients.
- Conditions
- Out-of-Hospital Cardiac Arrest, Blood Pressure, Hemodynamic Instability
- Trial name
- BOX (NCT03141099)
- Testing
- Low normal MAP, High normal MAP, Low normal PaO2.
- Where
- 2 sites in Denmark
- Volunteers
- 802 people
- Sponsor
- Jesper Kjaergaard
Cardiopulmonary Resuscitation
The Effect Of Simulation-Supported Pediatric CPR Training Based On CRM On Knowledge, Attitude, And Performance
Crew Resource Management is a training system that aims to use all available resources effectively and increase safety by improving technical knowledge and skills as well as non-technical skills in risky tasks such as CPR.
- Trial name
- NCT06341218
- Testing
- Pediatric Cardiopulmonary Resuscitation Training Based On Team Resource Management
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Out-Of-Hospital Cardiac Arrest
Post-resuscitation Care Registry for Survival From Out-of-hospital Cardiac Arrest
The aim of this study is to construct multi-center post-cardiac arrest care registry that can be used for data warehousing and clinical research.
- Trial name
- NCT03695718
- Where
- 3 sites in South Korea
- Volunteers
- 1,057 people
- Sponsor
- Seoul National University Hospital
Sepsis, Liver Failure
Lactate Clearance According to the Presence of Hepatic Dysfunction
The purpose of this study is to compare lactate clearance in patients with severe sepsis and septic shock according to the presence of hepatic dysfunction.
- Trial name
- NCT01709565
- Where
- South Korea
- Volunteers
- 245 people
- Sponsor
- Samsung Medical Center
Cardiac Arrest (CA)
Hand vs. Foot Chest Compressions in Simulation
Cardiopulmonary resuscitation (CPR) is essential in the management of cardiorespiratory arrest (CA) to improve survival rates. High-quality chest compressions are the primary intervention to maintain circulation and oxygenation…
- Trial name
- NCT07074080
- Testing
- Performing chest compressions on a mannequin using the foot, Performance of standard chest compressions with the upper limbs.
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Cardiopulmonary Arrest, Pediatric ALL
Impact of a mHealth Supportive Tool on Cardiopulmonary Resuscitation' Situational Awareness
This study will be a prospective, single-center, randomized controlled trial in a tertiary pediatric emergency department with two parallel groups of voluntary pediatric physicians and nurses.
- Conditions
- Cardiopulmonary Arrest, Pediatric ALL, Resuscitation
- Trial name
- InterFACE (NCT04464603)
- Testing
- InterFACE (mHealth tool), Conventional methods
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Cardiopulmonary Resuscitation
Pilot Study Comparing Ventilation Modes During CPR With Mechanical Compression Device.
Comparison of three ventilation modes (volume controlled, BIPAP and CPAP) during cardiopulmonary re-suscitation with a mechanical compression device in the emergency room.
- Trial name
- COVME (NCT03347175)
- Testing
- Volume controlled ventilation, Pressure controlled ventilation, CPAP mode
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Basic Cardiac Life Support, Cardiopulmonary Resuscitation
The Effect of T-CPR on the Quality of CPR and AED Use
The purpose of the study is to examine the effect of telephone assistance and standardized basic life support courses on the quality of cardiopulmonary resuscitation (CPR) and the use of automated external defibrillator (AED).
- Trial name
- NCT03690102
- Testing
- T-CPR, ERC standardized BLS course
- Where
- Denmark
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Respiration; Insufficient or Poor, Newborn, Infant, Premature, Diseases
Comparison Of Respiratory Support After Delivery on Infants Born Before 28 Weeks Gestational Age
Trial purpose: For infants born <28 weeks of age, can initial respiratory resuscitation with new system (low imposed work of breathing and prongs) reduce the frequency of delivery room intubations compared to standard treatment…
- Trial name
- CORSAD (NCT02563717)
- Testing
- T-piece used for respiratory support (several manufacturers), New system used for respiratory support
- Where
- 6 sites in Iceland, Lithuania and 3 more
- Volunteers
- 250 people
- Sponsor
- Baldvin Jonsson
Delivery Room Resuscitation
Quantitative End Tidal CO2 Monitoring in the Delivery Room (DR)
This is a trial evaluating the use of an end tidal CO2 monitor during ventilation in the delivery room. The use of the monitor is compared with clinical assessment of ventilation.
- Trial name
- NCT01381068
- Testing
- End tidal CO2 monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Neil Finer
Post-Resuscitation Syndrome, Critical Illness
Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest
This retrospective observational cohort study aims to identify early predictors of short- and mid-term mortality in adult patients who achieved return of spontaneous circulation (ROSC) after cardiac arrest.
- Conditions
- Post-Resuscitation Syndrome, Critical Illness, Cardiac Arrest, Hypoxic-Ischemic Encephalopathy
- Trial name
- PROM-ROSC (NCT07020091)
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Ahmet Düzgün
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Respiration; Insufficient or Poor, Newborn
Mask Ventilation With Different Face Masks During Neonatal Resuscitation
Most premature babies have difficulty breathing at birth and need help (what we call resuscitation). The treatment for this is to gently inflate their lungs with a resuscitation device and a facemask.
- Trial name
- NCT01685697
- Testing
- Mask ventilation with a Laerdal face mask, Mask ventilation with a F&P face mask
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Extracorporeal Membrane Oxygenation Complication, Cardiopulmonary Arrest
Registry Study of Extracorporeal Cardiopulmonary Resuscitation (eCPR) in China
The data of patients undergo extracorporeal cardiopulmonary resuscitation (eCPR) will be collected and analyzed. This study will provide useful information about the indication, the start time and others to improve the outcome of…
- Trial name
- ECPR-China (NCT04956497)
- Testing
- extracorporeal membrane oxygenation (ECMO)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Cardiac Arrest
Sustained Inflation and Chest Compression vs 3:1 C:V Ratio in Asphyxiated Newborns
Newborn infants who require cardiopulmonary resuscitation at birth receive chest compression using a 3-Compression to 1-Ventilation (3:1 C:V) ratio.
- Trial name
- SUR1VE-2 (NCT06577818)
- Testing
- CC+SI (Chest compression during sustained inflation), 3:1 C:V (3:1 Compression:Ventilation ratio)
- Where
- Canada
- Volunteers
- 554 people
- Sponsor
- University of Alberta
Cardiac Arrest
Comparing Therapeutic Hypothermia Using External and Internal Cooling for Post-Cardiac Arrest Patients
Controlled therapeutic hypothermia is a method of preserving neurological function post-resuscitation.It has been associated with improved functional recovery and reduced histological deficits in animal models of cardiac arrest.
- Trial name
- Hypothermia (NCT00827957)
- Testing
- Internal Cooling, External Cooling
- Where
- 2 sites in Singapore
- Volunteers
- 51 people
- Sponsor
- Singapore General Hospital
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