Clinical trials: Resuscitations
Cardiac Arrest, Cardiopulmonary Arrest
Use of a Feedback Device to Limit Too Shallow Compressions Associated With the Use of an I-gel® Device
Airway management in out-of-hospital cardiac arrest is still debated. Several options exist: bag-valve-mask ventilation, supraglottic devices and endotracheal intubation.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation, Emergency Medicine
- Trial name
- NCT05709613
- Testing
- Use of a chest compressions' feedback device
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Alzheimer Disease, Dementia
Pragmatic Trial of Video Education in Nursing Homes
This is a pragmatic cluster-randomized control trial (RCT) of an Advance Care Planning (ACP) Video Program for nursing home (NH) patients ≥ 65 years old who are cared for in 360 NH facilities (intervention arm n=119; control arm…
- Conditions
- Alzheimer Disease, Dementia, Heart Failure, Pulmonary Disease, Chronic Obstructive
- Trial name
- PROVEN (NCT02612688)
- Testing
- ACP Video Program
- Where
- 2 sites in United States
- Volunteers
- 197,692 people
- Sponsor
- Brown University
Sudden Death, Sudden Cardiac Arrest
Impact of an Intensive Care Diary on Post-traumatic Stress Disorder After a Resuscitated Sudden Death
Sudden death is a public health problem with more than 300,000 cases per year in USA and 40,000 cases per year in France. Moreover, despite all recent therapeutic improvements (therapeutic hypothermia, new techniques of…
- Trial name
- COREABOR (NCT02874469)
- Testing
- Diary
- Where
- France
- Volunteers
- 173 people
- Sponsor
- University Hospital, Lille
CPR Quality Assessment
Effectiveness of Chest Compressions With Standard vs Feedback-Assisted CPR
The objective of this educational clinical trial is to compare auditory (metronome) and audiovisual (TrueCPR) feedback systems with both standard CPR and with each other in a simulated environment, focusing on their effects on…
- Trial name
- NCT07029724
- Testing
- TrueCPR Multisensory Feedback Device, Ambu Smartman ALS Pro+ (AW301) Simulation Manikin, Metronome
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Betül Akbuğa Özel
Septic Shock, Severe Sepsis
Early Use of Norepinephrine in Septic Shock Resuscitation
Current septic shock guideline recommends fluid resuscitation as the first treatment. Vasopressors, including norepinephrine is recommended to start after achieve adequate fluid therapy.
- Trial name
- CENSER (NCT01945983)
- Testing
- Early norepinephrine
- Where
- Thailand
- Volunteers
- 310 people
- Sponsor
- Mahidol University
CABG Surgery
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for CABG Surgery
After obtaining approval from the Institutional Review Board of our institution, written informed consent is obtained from patients undergoing CABG surgery are enrolled in this prospective study and randomly allocated into one of…
- Trial name
- NCT02757027
- Testing
- Intravenous Crystalloid, Intravenous HES
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Facial Paralysis
3D Dynamic and Patient-Centered Outcomes of Facial Reanimation Surgery in Patients With Facial Paralysis
In this study, patients who have undergone facial paralysis surgery will be asked to participate. The goal of this study is to compare the facial disability and perception outcomes of facial reanimation surgeries in patients with…
- Trial name
- NCT04934176
- Testing
- Psychosocial scales/questionnaires, 3D Facial Measurements
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Tufts University
Cardiopulmonary Arrest, Pediatric ALL
Impact of a mHealth Supportive Tool on Cardiopulmonary Resuscitation' Situational Awareness
This study will be a prospective, single-center, randomized controlled trial in a tertiary pediatric emergency department with two parallel groups of voluntary pediatric physicians and nurses.
- Conditions
- Cardiopulmonary Arrest, Pediatric ALL, Resuscitation
- Trial name
- InterFACE (NCT04464603)
- Testing
- InterFACE (mHealth tool), Conventional methods
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Sepsis
Early Resuscitation in Paediatric Sepsis Using Inotropes
Septic shock in children still carries substantial mortality and morbidity. While resuscitation with 40-60 mL/kg intravenous fluid boluses remains a cornerstone of initial resuscitation, an increasing body of evidence indicates…
- Trial name
- ANDES-CHILD (NCT06478797)
- Testing
- Fluid, Adrenalin
- Where
- 4 sites in Argentina, Bolivia and 1 more
- Volunteers
- 40 people
- Sponsor
- NATALIA LOPERA MUNERA
Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR)
The AIR-CPR Study: AI-Guided Chest Compressions
The AIR-CPR project aims to improve survival rates for patients with Out-of-Hospital Cardiac Arrest (OHCA) by utilizing Artificial Intelligence (AI) to optimize chest compression locations.
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR), Aortic Valve Compression, Precision Resuscitation
- Trial name
- AIR-CPR (NCT07431710)
- Testing
- Device: AI-Enhanced Arterial Waveform Monitor (AIR-CPR App), AI-Guided Chest Compression Repositioning, Transesophageal Echocardiography (TEE)
- Where
- Taiwan
- Volunteers
- 255 people
- Sponsor
- Far Eastern Memorial Hospital
Delivery Room Resuscitation
Quantitative End Tidal CO2 Monitoring in the Delivery Room (DR)
This is a trial evaluating the use of an end tidal CO2 monitor during ventilation in the delivery room. The use of the monitor is compared with clinical assessment of ventilation.
- Trial name
- NCT01381068
- Testing
- End tidal CO2 monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Neil Finer
Total Fluid Volume Increased
Effect of Fluid Resuscitation and Microcirculation
Although the investigators take many measurements to monitor the fluid state of the patients, it is not known exactly whether the fluid has real effect on the organ perfusion.
- Trial name
- NCT01369524
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Frisius Medisch Centrum
Sepsis, Systemic Inflammatory Response Syndrome
PPV to Guide Fluid Management in the PICU
Children who are critically ill often require large amounts of fluid during their acute illness. It has been shown in multiple studies that appropriate administration of fluid decreases morbidity and mortality, but giving too…
- Trial name
- PPV (NCT02308371)
- Testing
- Automated Pulse Pressure Variation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Heart Arrest
BC ECPR Trial for Out-of-Hospital Cardiac Arrest
The addition of an Extracorporeal-Cardiopulmonary Resuscitation (ECPR) service to a region may improve the survival of young patients with sudden unexpected cardiac arrest.The primary aim of this study is to determine the benefit…
- Trial name
- NCT02832752
- Testing
- ECPR Protocol
- Where
- 3 sites in Canada
- Volunteers
- 308 people
- Sponsor
- University of British Columbia
Cardiac Arrest
Videolaryngoscopy During Child Intubation
We hypothesized that the video-laryngoscopes are beneficial for intubation of pediatric manikins while performing CPR. In the current study, we compared effectiveness of three video-laryngoscopes and Macintosh (MAC) laryngoscopes…
- Trial name
- NCT02289664
- Testing
- MAC, Coopdech, CoPilot
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Out-Of-Hospital Cardiac Arrest
CPR Quality and Use of Feedback for OHCA
The purpose of this study is to investigate the quality of cardio-pulmonary resuscitation(CPR) delivered by EMS professionals and whether this quality can be improved by implementing real-time feedback during the event and an…
- Trial name
- NCT04152252
- Testing
- Real time feedback, Post-event debriefing
- Where
- Denmark
- Volunteers
- 2,989 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Communication, Advance Directives
Choice of Diction's Effect
The purpose of the research is to determine how the language used when discussing preferences about cardiopulmonary resuscitation (CPR) affects decisions regarding this (code status)
- Conditions
- Communication, Advance Directives, Decision Making, Cardiopulmonary Resuscitation
- Trial name
- CODE (NCT04896411)
- Testing
- Alternative phrasing for no code, Standard of care for no code
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Burns
Pre-hospital Care in Burn Patients Presenting to Tertiary Care Centers of Nepal
This cross-sectional study investigates pre-hospital practices among burn patients presenting to a tertiary care center in Nepal.
- Trial name
- NCT06779500
- Where
- Nepal
- Volunteers
- 196 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Cardiac Arrest
AutoPulse Assisted Prehospital International Resuscitation Trial (ASPIRE)
The AutoPulse Assisted Prehospital International Resuscitation (ASPIRE) Trial compares the efficacy of circulatory assist by manual chest compression versus an automated chest compression device (AutoPulse™) during the…
- Trial name
- NCT00120965
- Testing
- AutoPulse, Manual CPR
- Where
- United States
- Volunteers
- 1,837 people
- Sponsor
- University of Washington
Heart; Arrest, Newborn, Birth Asphyxia
Does Higher (100% Oxygen) Versus Lower (21% Oxygen) During CC+SI During CPR of Asphyxiated Newborns Improve Time to ROSC
When newborn babies are born without a heartbeat the clinical team has to provide breathing and chest compressions (what is call cardiopulmonary resuscitation) to the newborn baby.
- Conditions
- Heart; Arrest, Newborn, Birth Asphyxia, Bradycardia Neonatal
- Trial name
- SURV1VE-O2 (NCT03902652)
- Testing
- Intervention (21% oxygen during CC+SI), Intervention (100% oxygen during CC+SI)
- Where
- Canada
- Sponsor
- University of Alberta
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