Clinical trials: Retention, Urinary, open to volunteers
Spinal Anesthesia, Postoperative Complications
D-FAB-POUR Trial: Dexmedetomidine vs Fentanyl as Adjuvants to Bupivacaine on Postoperative Urinary Retention
This study aims to compare two medications, dexmedetomidine and fentanyl, when used alongside a commonly used spinal anesthetic called bupivacaine in patients undergoing lower limb surgery.
- Conditions
- Spinal Anesthesia, Postoperative Complications, Dexmedetomidine, Fentanyl
- Trial name
- D-FAB-POUR (NCT07117565)
- Testing
- Intervention 1: Intrathecal Dexmedetomidine with Bupivacaine, Intervention 2: Intrathecal Fentanyl with Bupivacaine
- Where
- Nepal
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Acute Urinary Retention, Benign Prostatic Hyperplasia
Tamsulosin Dose Escalation or Silodosin Switch Before Trial Without Catheter in BPH-Related Acute Urinary Retention
This randomized controlled trial will compare three medication strategies before trial without catheter in men with acute urinary retention due to benign prostatic hyperplasia who were already taking tamsulosin 0.4 mg once daily…
- Trial name
- NCT07650968
- Testing
- Tamsulosin 0.4 mg, Tamsulosin 0.8 mg, Silodosin 8 mg
- Where
- Egypt
- Volunteers
- 378 people
- Sponsor
- Beni-Suef University
Urinary Retention
Post Operative Urinary Retention (POUR) Following Thoracic Oncological Surgery
This is a feasibility study looking at whether the use of Tamsulosin could lower the high incidence of postoperative urinary retention (POUR) in older men who undergo an oncological thoracic surgical procedure for suspected or…
- Trial name
- NCT05657990
- Testing
- Tamsulosin
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Hackensack Meridian Health
BPH With Urinary Obstruction
PUL vs TURP in BPH Patients With Urinary Retention
The study will be a prospective, randomized controlled trial comparing prostatic urethral lift (PUL) versus transurethral resection of prostate (TURP) in benign prostate hyperplasia (BPH) patients with urinary retention.
- Trial name
- PULTUR (NCT06037356)
- Testing
- Prostatic Urethral Lift, TURP
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Postoperative Urinary Retention, Urinary Retention
Evaluating Two Nursing Interventions to Prevent Urinary Retention After Spinal Anesthesia
The goal of this clinical trial is to learn whether two simple nursing methods can help prevent trouble emptying the bladder (acute urinary retention, AUR) after surgery with numbing medicine in the lower back (spinal…
- Trial name
- NCT07293000
- Testing
- Suprapubic Cold Pack, Sacral Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Istanbul University - Cerrahpasa
Neurogenic Bladder, Urinary Retention
Effect of Chlorhexidine Gluconate Bladder Instillations in Patients With Chronic Suprapubic Catheters on Unplanned Healthcare Encounters and Quality of Life
The goal of this clinical trial is to evaluate the feasibility and tolerability of 0.05% Chlorhexidine Gluconate (CGH) bladder instillations in an outpatient setting at the time of suprapubic catheter (SPC) exchange in patients…
- Trial name
- NCT06163469
- Testing
- Bladder instillation with Irrisept
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Yale University
Acute Urinary Retention, Benign Prostate Hypertrophy(BPH)
Study of Teverelix DP on Prostate Volume, Urinary Function and Clinical Outcomes Following Acute Urinary Retention
This randomized, double-blind, placebo-controlled Phase 2 study is evaluating Teverelix DP in men following a first episode of acute urinary retention (AUR) associated with benign prostatic hyperplasia (BPH), a population at risk…
- Trial name
- NCT07733934
- Testing
- Teverelix DP
- Volunteers
- 126 people
- Sponsor
- Antev Ltd.
Urinary Retention, Urinary Retention After Procedure
Rectus Abdominis Detrusor Myoplasty for Urinary Retention
This investigates the outcomes of a surgical technique using the patient's own abdominal wall muscles to help contract the bladder in patients with urinary retention
- Conditions
- Urinary Retention, Urinary Retention After Procedure, Urinary Retention Postoperative
- Trial name
- RADM (NCT07379814)
- Testing
- Rectus Abdominal Detrusor Myoplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University Hospitals Cleveland Medical Center
Arthroplasties, Knee Replacement, Nerve Block
Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine
Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs.
- Conditions
- Arthroplasties, Knee Replacement, Nerve Block, Urinary Retention Postoperative, Anesthesia, Spinal
- Trial name
- POURRKA (NCT07050277)
- Testing
- Intrathecal Morphine, No Intrathecal Morphine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Urinary Retention
Evaluation of the Efficacy of the Addition of Magnesium Sulfate to Morphine on the Occurrence of Acute Urinary Retention Following Epidural Anesthesia for Cesarean Section.
Peri-medullary anesthesia is the preferred anesthetic technique for Caesarean surgery. Compared with general anesthesia, it reduces maternal and fetal morbidity and mortality, as well as postoperative pain.
- Trial name
- EPIMAG (NCT06442995)
- Testing
- Injection of 500 mg magnesium sulfate + 2 mg morphine into the epidural space, Injection of Isotonic saline + 2 mg morphine into the epidural space
- Where
- France
- Volunteers
- 290 people
- Sponsor
- CHU de Reims
Postpartum Urinary Retention
Effect of Voiding Position (Standing in the Shower vs. Sitting) on Post- Void Residual Urine Volume (PVR) After Removal of Urinary Catheter in Women Following Vaginal Delivery With Epidural Analgesia: A Double- Blind Randomized Controlled Trial
Postpartum urinary retention is a common complication after childbirth, with a higher risk for women who undergo vaginal delivery with epidural analgesia.
- Trial name
- NCT07893119
- Testing
- Standing in the shower, Sitting on the toilet
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Urinary Retention Postoperative
Prevention of Post Operative Urinary Retention After Thoracic Surgery Trial
The objectives of this study are to determine the feasibility of conducting a full-scale randomized control trial comparing the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention in people…
- Trial name
- PrePOURTS (NCT06262048)
- Testing
- Tamsulosin Hydrochloride
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Urinary Retention, Colorectal Surgery
Prophylactic Use of Tamsulosin in the Prevention of Post-operative Urinary Retention in Men After Rectum Resection
The study will be a phase III double-blind randomized clinical trial. Participants will be recruited from the Department of General Surgery of the CHU de Québec - Saint-François-d'Assise and Hôtel-Dieu de Québec.
- Conditions
- Urinary Retention, Colorectal Surgery, Rectal Resection, Post-operative Urinary Retention
- Trial name
- R-POUR (NCT05941806)
- Testing
- pr Sandoz Tamsulosin, Glucose
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Acute Urinary Retention, Benign Prostatic Hyperplasia
Tamsulosin With or Without Tadalafil for Trial Without Catheter After Acute Urinary Retention Due to Benign Prostatic Hyperplasia
Acute urinary retention is a common emergency in men with benign prostatic hyperplasia. After bladder drainage with a urethral catheter, patients usually undergo a trial without catheter to determine whether they can pass urine…
- Conditions
- Acute Urinary Retention, Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
- Trial name
- TAMS-TAD-TWOC (NCT07654413)
- Testing
- Tamsulosin, Tadalafil
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Beni-Suef University
BPH With Symptomatic Lower Urinary Tract Symptoms, BPH With Urinary Obstruction
Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate
Many consider laser enucleation of the prostate the new 'gold standard' for the surgical treatment of benign prostatic hyperplasia (BPH) due to its excellent outcomes, high success rates, and long-term efficacy.
- Trial name
- NCT07187180
- Testing
- holmium laser, pulsed thulium laser
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Smita De
Postoperative Urinary Retention (POUR)
Peri-operative Tamsulosin and Impact on Voiding Trial After Same-day Urogynecology Surgery
The purpose of this research study is to determine if taking tamsulosin preoperatively decreases your chances of being discharged after surgery with a Foley catheter (flexible tube that drains urine from the bladder into a…
- Trial name
- NCT06843538
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- TriHealth Inc.
Pregnant Women, Cesarean Section
Evaluation of the Absence of Intraoperative Bladder Catheterization in Case of Planned Cesarean Section
The hypothesis of this trial is that the absence of systematic bladder catheterization in patients performing spontaneous urination in the hour preceding the planned cesarean section under spinal anesthesia would not lead to more…
- Trial name
- C2S (NCT06357546)
- Testing
- Spontaneous urination during the hour before caesarean section., Systematic bladder catherization during caesarean section.
- Where
- 2 sites in France
- Volunteers
- 550 people
- Sponsor
- University Hospital, Montpellier
Retention, Urinary
Exploratory Study Investigating the Urinary Bladder During Intermittent Catheterization in Healthy and Spinal Cord Injured Male and Female Subjects Using an Upright MRI Scanner
This is an exploratory study investigating morphological and physiological changes of the lower urinary tract and surrounding structures during IC use in individuals with SCI, and during normal voiding and IC use in healthy…
- Trial name
- NCT07384559
- Testing
- MRI scan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Incontinence, Neurogenic Bladder Dysfunction
RElax & feeL at EASE (RELEASE)
This multicenter, parallel-group, randomized controlled trial (RELEASE) aims to evaluate the efficacy of two educational approaches on acceptance and adherence to intermittent catheterization (IC) among adult male patients.
- Conditions
- Incontinence, Neurogenic Bladder Dysfunction, Urinary Retention
- Trial name
- RELEASE (NCT07084376)
- Testing
- Enhanced Educational Program for Intermittent Catheterization, Standard Education Group
- Volunteers
- 64 people
- Sponsor
- Stefania Musco
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
Selective Median Lobe Surgery Outcomes Study
This prospective multicenter observational cohort study will evaluate clinical outcomes after selective median lobe transurethral surgery for benign prostatic obstruction.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH), Benign Prostatic Obstruction, Urinary Retention
- Trial name
- UNVEIL-BPO (NCT07699718)
- Testing
- Selective Median Lobe TURP, Selective Median Lobe HoLEP/AEEP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 420 people
- Sponsor
- Necmettin Erbakan University