Clinical trials: Retention
Gingival Diseases
Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.
Clinical research study to determine the anti-plaque efficacy of prototype dentifrices via a 4-day brushing regiment
- Trial name
- NCT00966953
- Testing
- Fluoride, Triclosan/Fluoride toothpaste, antibacterial plant extract
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Relapsing Remitting Multiple Sclerosis
Evaluation of Patient Retention of Fingolimod vs. Currently Approved Disease Modifying Therapy in Patients With Relapsing Remitting Multiple Sclerosis.
A 12 month study where 852 patients with relapsing remitting MS will be randomized 1:1 to fingolimod or approved disease modifying therapy.
- Trial name
- PREFERMS (NCT01623596)
- Testing
- Fingolimod, Disease Modifying therapy
- Where
- 123 sites in United States, Puerto Rico
- Volunteers
- 881 people
- Sponsor
- Novartis Pharmaceuticals
Denture Retention
A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers
The purpose of this study is to evaluate a methodology to determine the ability of a denture adhesive to restrict food ingress underneath dentures during eating.
- Trial name
- NCT03345108
- Testing
- Denture Adhesive Cream (Conventional Application), Denture Adhesive (Continuous Strip Application), No Adhesive
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Abortion, Second Trimester, PPROM
Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial
When time allows, administration of mifepristone prior to second trimester induction of labor decreases total labor time. However, in the setting of many pregnancy complications, decreasing time from diagnosis of nonviable…
- Conditions
- Abortion, Second Trimester, PPROM, Rupture, Spontaneous, Fetal Demise
- Trial name
- MIST (NCT05322252)
- Testing
- Mifepristone, Misoprostol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Urinary Retention
A Confirmatory Study Confirming Performance of a New Intermittent Catheter
A multi-centre, randomized, controlled crossover design. The total study duration for the individual subject was approximately 9 weeks.
- Trial name
- NCT05485935
- Testing
- Investigational device - intermittent catheter with micro-hole zone, Comparator - standard intermittent catheter
- Where
- 6 sites in Denmark, France and 2 more
- Volunteers
- 73 people
- Sponsor
- Coloplast A/S
Stress and Burnout
Certified Nursing Assistants' Wellbeing
Certified nursing assistants (CNAs), who provide the majority of care to persons with chronic disease and/or cognitive impairment from Alzheimer's disease and related dementias, face tremendous job and home stress, and as a…
- Trial name
- CNA (NCT03720652)
- Testing
- 8-Week Mindful Self-Compassion (MSC), 6-Week Mindful Self-Compassion (MSC)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Bladder Dysfunction, Urinary Retention
Patient-operated Valved Catheter Versus Indwelling Transurethral Catheter
Following surgery for female urinary incontinence and/or pelvic organ prolapse, women are sometimes temporarily unable to empty their bladders and are sent home with a transurethral indwelling catheter attached to a bag which…
- Trial name
- NCT01460303
- Testing
- Bladder catheter: OPTION-vf patient controlled catheter vs. indwelling transurethral catheter with leg bag, Transurethral catheter with leg bag
- Volunteers
- 49 people
- Sponsor
- University of Massachusetts, Worcester
Intrauterine Device Complications, Contraceptive Device Failure
Patient Factors Associated With Fragmentation of Copper Intrauterine Device (IUD) Requiring Hysteroscopic Removal
The purpose of this retrospective chart review was to identify risks factors for patients associated to Cooper IUD fragmentation upon removal resulting in the requirement of a hysteroscopy evaluation.
- Conditions
- Intrauterine Device Complications, Contraceptive Device Failure, IUD Fragmentation, Retained Intrauterine Device
- Trial name
- NCT07351084
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Kansas Medical Center
Obesity
Prevention of Postpartum Weight Retention in Low Income WIC Women
This study will examine the effects of an online behavioral intervention to promote weight loss in low income postpartum women in the WIC program.
- Trial name
- NCT01408147
- Testing
- Online postpartum weight control
- Where
- 2 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Denture Retention
Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress
In this clinical study, an experimental denture adhesive with a precision tip nozzle was tested to evaluate the relative efficacy to reduce the ingress of food under the denture compared to use of no adhesive or a standard…
- Trial name
- NCT02928380
- Testing
- Experimental Denture Adhesive, Reference (Marketed) Denture Adhesive
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetes, Gestational, Gestational Weight Gain
Meals for Moms: Medically-Tailored Meals for Women Who Had Gestational Diabetes
The purpose of this research study is to test whether delivery of medically tailored meals (meals designed specifically to be healthy) can be used to help reduce high blood sugar after delivery of a baby.
- Conditions
- Diabetes, Gestational, Gestational Weight Gain, Postpartum Weight Retention
- Trial name
- NCT04866823
- Testing
- Medically Tailored Meals
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wake Forest University Health Sciences
Basic Life Support, Cardiac Arrest
Mastery Learning Versus Time-based Education: Skill Acquisition and Retention of Basic Life Support in Laypeople
Background: In cardiac arrest survival rates dramatically increase when bystanders are present and initiate Basic Life Support (BLS).
- Trial name
- NCT02059395
- Testing
- Mastery based learning, Time based learning
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Urinary Retention
Peppermint Oil for Urinary Retention
A randomized controlled study will be conducted, with two arms. Postpartum women experiencing urinary retention will be randomized into one of the two following arms: Arm 1: Subjects will be exposed to vapor of peppermint oil Arm…
- Trial name
- NCT05259800
- Testing
- Peppermint oil vapors, Mineral Oil
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Opioid Use
FOREward Together: Training Peer Recovery Coaches to Promote Retention and Adherence to MOUD
This project aims to implement a peer-led intervention to support retention and adherence to medications for opioid use disorder among low-income adults in Detroit, as well as a training manual for peer recovery coaches serving…
- Trial name
- NCT05098795
- Testing
- Behavioral Activation (BA)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Henry Ford Health System
Opioid Use, Opioid-use Disorder
Providing Suboxone and PrEP Using Telemedicine
The purpose of this study is to provide medication for opioid use disorder (MOUD) with buprenorphine and naloxone, or bup/nx, and pre-exposure prophylaxis (PrEP) for HIV prevention for persons who inject opioids accessing syringe…
- Conditions
- Opioid Use, Opioid-use Disorder, Risk Reduction, Hiv
- Trial name
- NCT04521920
- Testing
- Suboxone, PrEP
- Where
- 3 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Duke University
Urinary Retention, Urinary Incontinence
Autologous Muscle Derived Cells for Underactive Bladder
This is a prospective, open-label, Phase 1, single center study evaluating the safety and efficacy of Autologous Muscle Derived Cells as a treatment for chronic Underactive Bladder.
- Trial name
- NCT02463448
- Testing
- Autologous Muscle Derived Cells
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Jason Gilleran
Postoperative Urinary Retention
Self-discontinuation of a Transurethral Catheter
This study is to determine if self-discontinuation of transurethral foley catheters in patients diagnosed with postoperative urinary retention (POUR), which is defined as the continued need for catheterization, following…
- Trial name
- NCT02996968
- Testing
- Self-removal
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- TriHealth Inc.
Urinary Retention, Voiding Disorders
Urinary Retention After Total Laparoscopic Hysterectomy With Immediate Foley Catheter Removal Versus Backfill Void Trial
Acute urinary retention is a complication of hysterectomies that can result in bladder over-distension and long term bladder dysfunction.
- Trial name
- NCT03141372
- Testing
- Void Trial using Foley catheter
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Sara Farag
Retention, Urinary
New Coating for Urinary Intermittent Catheters
The goal is to confirm, that the newly developed coating is non-inferior to the comparator with respect to the overall discomfort of the catheterisation (assessed by participant).
- Trial name
- NCT06985888
- Testing
- SpeediCath® Standard male new coating, SpeediCath® Standard male
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Urinary Retention, Underactive Bladder
Pudendal Nerve Mapping Towards Improved Neuromodulation for Urinary Retention
This study is to map the pudendal nerve. In this study the researchers will examine subjects who are already receiving an implanted stimulator at their pudendal nerve as part of their normal clinical care.
- Trial name
- NCT04236596
- Testing
- Participants received a Neurostimulator, which was used to map the pudendal nerve
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan