Clinical trials: Retention in Care
HIV Infection, Adherence
Social Norms and Priming to Improve Adherence to Antiretroviral Therapy and Retention in Care
Interventions incorporating constructs from behavioral economics and psychology have the potential to enhance HIV 'treatment as prevention' (TasP) strategies.
- Trial name
- NCT02938533
- Testing
- Intervention
- Where
- 2 sites in Tanzania
- Volunteers
- 438 people
- Sponsor
- University of California, Berkeley
HIV/AIDS
Epividian / AHF: Positive Pathways - HIV Retention in Care
The primary objective of this study is to evaluate the effectiveness of a clinical decision support system (CDSS) combined with enhanced patient contact to retain HIV+ patients in care with AIDS Healthcare Foundation.
- Trial name
- NCT04147832
- Testing
- Alert to provider
- Where
- United States
- Volunteers
- 10,521 people, healthy volunteers welcome
- Sponsor
- Epividian
Depression in Adolescence, Suicide Prevention
Strategic Treatment and Assessment for Youth (STAY)
This multi-method, multi-phase pilot trial is designed to explore initial implementation and effectiveness of a theoretically-driven, culturally-tailored, measurement-based care (MBC) approach, Strategic Treatment Assessment for…
- Trial name
- STAY (NCT06515236)
- Testing
- Strategic Treatment Assessment for Youth (STAY), Measurement Based Care As Usual
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
HIV/AIDS, Cryptococcal Meningitis
Vietnam Cryptococcal Retention in Care Study - Version 2.1
This is a multicenter prospective cohort evaluation of the implementation of a cryptococcal antigen (CrAg) screening program at selected outpatient HIV clinics (OPCs) and network laboratories in Vietnam.
- Conditions
- HIV/AIDS, Cryptococcal Meningitis, Opportunistic Infections, HIV Related, Cryptococcosis
- Trial name
- NCT03267407
- Testing
- Preemptive high-dose Fluconazole
- Where
- Vietnam
- Volunteers
- 1,184 people
- Sponsor
- National Hospital for Tropical Diseases, Hanoi, Vietnam
HIV/AIDS
Retention in HIV Care for Hispanic Immigrants
A randomized trial to test the feasibility and acceptability of an intervention to improve retention in HIV primary care in HIV-infected Hispanic immigrants compared to a "treatment as usual" condition.
- Trial name
- ADELANTE (NCT03484117)
- Testing
- Community Health Worker
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Massachusetts General Hospital
Edentulous Mouth, Edentulous Jaw
Single-implant Overdentures Retained by the Novaloc Attachment System
The objective of this explanatory mixed methods study is to compare a novel attachment system (Novaloc) to a traditional alternative (Locator) for single implants in the mandible of edentate elders.
- Trial name
- NCT03126942
- Testing
- Novaloc, Locator
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University
Infertility
Does a Brief Intervention Decrease Patient Drop Out Rates?
The goal of this study is to determine a) if a follow-up email to selected patients who had an initial consult with an infertility specialist, but did not return for a second visit, would change return to care behavior and b) why…
- Trial name
- NCT04803045
- Testing
- Follow up email
- Where
- United States
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- Boston IVF
HIV Antiretroviral Therapy (ART) Adherence, PMTCT
Optimizing Prevention and Care for Pregnant and Postpartum Adolescent Girls and Young Women With HIV in Tanzania
The goal of this clinical trial is to find better ways to care for pregnant and postpartum adolescent girls and young women (AGYW) aged 15-24 years with HIV in Tanzania, and to prevent them from passing HIV to their babies.
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, PMTCT, Pregnancy, Retention in Care
- Trial name
- ENGAGE (NCT06605053)
- Testing
- Co-produced intervention to optimize PMTCT care engagement
- Where
- 2 sites in Tanzania
- Volunteers
- 222 people
- Sponsor
- Karolinska Institutet
PrEP Uptake
PrEP Optimization Among Women to Enhance Retention and Uptake
Black women experience one of the highest incidences of HIV among all subpopulations in the United States, but pre-exposure prophylaxis (PrEP) use among Black cisgender women is very limited.
- Trial name
- POWER Up (NCT05626452)
- Testing
- PrEP Education, Provider training, EMR Optimization
- Where
- United States
- Volunteers
- 724 people, healthy volunteers welcome
- Sponsor
- University of Chicago
HIV
The TracTOR (Tracking and Tracing Operations Research) Study -- Zimbabwe
This study evaluates the effectiveness of an enhanced package of support for activities described in the "Standard Operating Procedures (SOP) for Patient Tracing in Health Facilities in Zimbabwe".
- Trial name
- TracTOR (NCT02552693)
- Testing
- Enhanced training, supervision and support
- Where
- Zimbabwe
- Volunteers
- 946 people
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
HIV/AIDS
Effectiveness of Peer Navigation and Contingency Management on Retention in HIV Care
Consistent treatment with anti-retroviral therapy (ART) suppresses viral load (VL), prolonging life and improving quality of life for HIV+ persons. Suppressing VL benefits communities by reducing transmission to others.
- Trial name
- CHAMPS (NCT02310893)
- Testing
- Combined Contingency Management and Peer Navigation, Contingency Management, Peer Navigation
- Where
- 6 sites in United States
- Volunteers
- 579 people
- Sponsor
- University of California, Los Angeles
HIV Infection
Effects of Facility-based Mother Support Groups on Prevention of mother-to Child Transmission Outcomes in Zimbabwe
The investigators hypothesize that a strategy of establishing facility-based mother support groups (MSGs) for HIV-positive mothers will result in increased retention rates of HIV-exposed infants in clinic-based PMTCT follow-up…
- Trial name
- EPAZ (NCT02216734)
- Testing
- Mother support groups for HIV+ mothers
- Where
- 2 sites in Zimbabwe
- Volunteers
- 300 people
- Sponsor
- Family AIDS Caring Trust
Basic Life Support
Early or Late Booster in Basic Life Support for Health Care Professionals
Attrition of skills after basic life support (BLS) training is common. Psychology studies have established that for basic memory recall tasks, spaced learning strategies improve retention.
- Trial name
- NCT03893253
- Testing
- Early Booster Teaching, Late Booster Teaching
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hopital Montfort
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Edentulous Mouth, Edentulous Jaw
Mandibular Overdentures Retained by Conventional or Mini Implants
This study aims to compare mandibular overdentures retained either by mini or standard size implants as a treatment for edentulous adults, in terms of patient-reported satisfaction and oral health-related quality of life.
- Trial name
- NCT01411683
- Testing
- Implant-retained mandibular overdenture
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
HIV
Assessment of a Community Support Worker Intervention for Persons Living With HIV (PLWH) in Rural Ethiopia
This study, to be conducted in southern Ethiopia, is a randomized community trial, evaluating the use of local community support workers who provide for HIV patients education, counseling/social support, and linkage to the HIV…
- Trial name
- SHAMA (NCT02448394)
- Testing
- Community Support Worker
- Where
- 5 sites in Ethiopia
- Volunteers
- 1,799 people
- Sponsor
- University of Minnesota
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans 3.0
Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Hypertension
- Trial name
- EMPOWER (NCT07356479)
- Testing
- EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
HIV
Texting to Improve Testing (TextIT):
Early accurate diagnosis is one of the first crucial steps in care for infants born to HIV-infected mothers. Early initiation of antiretroviral therapy (ART) relies upon early diagnosis and results in significant reductions in…
- Trial name
- TextIT (NCT02350140)
- Testing
- Text messaging from beginning, Text messaging after 6 months of control
- Where
- Kenya
- Volunteers
- 2,508 people
- Sponsor
- University of Washington
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans
Women Veterans are the fastest growing segment of VA users. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Smoking
- Trial name
- EMPOWER (NCT05050266)
- Testing
- EBQI, REP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Substance-Related Disorders, Opioid Medication Assisted Treatment
Peer Activate: Trial of Peer-Delivered Behavioral Activation for Methadone Adherence
The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for opioid use disorder (MOUD) among low-income, minority individuals…
- Conditions
- Substance-Related Disorders, Opioid Medication Assisted Treatment, Opioid Use Disorder, Opioid Use
- Trial name
- HEAL Together (NCT05299515)
- Testing
- Peer-Delivered Behavioral Activation ("Peer Activate")
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Maryland, College Park