Clinical trials: Retina Surgery
Epiretinal Membranes
Prognostic Factors in Epiretinal Membrane Surgery
Retrospective interventional case series study reporting preoperative clinical and anatomical factors associated with visual recovery 1 year after combined cataract and idiopathic epiretinal membrane surgery.
- Trial name
- NCT02406430
- Testing
- a combined cataract and ERM surgery
- Volunteers
- 142 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Epiretinal Membrane
Randomized Trial Comparing Epiretinal Membrane Surgery With and Without Internal Limiting Membrane Removal
Macular epiretinal membrane (ERM) is a semitranslucent, avascular, fibrocellular membrane on the inner surface along the internal limiting membrane (ILM) of the retina.
- Trial name
- NCT01532765
- Testing
- Pars plana vitrectomy and epiretinal membrane peel, ILM peel assisted by ICG, CE-IOL
- Where
- 3 sites in Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Epiretinal Membranes, Macular Holes
Blue-Blocking IOLs in Combined Surgery
Although commonly used in cataract surgery, the use of the blue light-filter IOLs in vitrectomy combined with cataract surgery has not been reported yet.
- Conditions
- Epiretinal Membranes, Macular Holes, Cataract
- Trial name
- NCT00537992
- Testing
- combined surgery
- Volunteers
- 60 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Optic Disc Structural Anomaly, Maculopathy
Surgical Management of Optic Disc Pit Maculaopathy
To evaluate the anatomical and functional results of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, endolaser photocoagulation and gas tamponade in management of optic disc pit (ODP)…
- Trial name
- NCT03185936
- Testing
- pars plana vitrectomy with internal limiting membrane (ILM) peeling
- Volunteers
- 9 people
- Sponsor
- Minia University
Macular Holes
To Evaluate the Therapeutic Efficacy of Hydrated Amniotic Membrane in Promoting Closure of Refractory Macular Holes.
To compare anatomic and functional results, and to evaluate postoperatively the healing process in 3 different techniques for the closure of the refractory macular holes (MH).
- Trial name
- NCT05396209
- Testing
- Hydrated Amniotic Membrane Plug, ILM filling, Conventional ILM peeling
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Oriental Neurosurgery Evidence-Based-Study Team
Macular Hole, Epiretinal Membrane
Optical Coherence Tomography - Rescan During Dissection of Macular Membranes
In our study , the investigators will use the microscope with OCT ( Lumera with RESCAN OCT ) coupled to assess the extent , depth and change of retinal architecture in the perioperative period .
- Conditions
- Macular Hole, Epiretinal Membrane, Traction Syndrome Vitreomacular, Proliferative Vitreoretinopathy
- Trial name
- NCT02748421
- Testing
- Lumera Microscope with OCT RESCAN, Conventional Microscope
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Macular Hole
Objective Evaluation of Postoperative Positioning in Macular Hole Surgery
The macular hole formation takes place in the centre of the retina. A closure of the macular hole is believed to take place if the central retinal area is kept dry in the postoperative period.
- Trial name
- NCT02295943
- Testing
- Positioning measuring device
- Where
- 4 sites in Norway
- Volunteers
- 205 people
- Sponsor
- Helse Stavanger HF
Macular Hole
Fundus Autofluorescence After Macular Hole Surgery
Funds autofluorescence (FAF) indicates hyper fluorescence at the macular hole in the patients with macular hole. Investigators investigate the association between FAF and visual acuity, recovery of foveal microstructure, and FAF…
- Trial name
- NCT02628262
- Testing
- Vitrectomy with internal limiting membrane removal and gas tamponade
- Where
- Japan
- Volunteers
- 27 people
- Sponsor
- Makoto Inoue
Rhegmatogenous Retinal Detachment
Axial Length Change in Eyes Treated by Silicone Sponge Scleral Buckling
All existing medical literatue regarding axial length (AL) changes after scleral buckling surgery for retinal detachment, descibes changes after solid silicone buckling.
- Trial name
- NCT01647373
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Macular Pucker
Compare ELP in Patients With Elective Phaco-VTX Surgery in One Eye and a Single Lens Phaco Surgery on the Other Eye
The aim of the study is to gain more insight into the potential impact of a vitrectomy (removal of the vitreous) on postoperative effective position of the intraocular lens (IOL).
- Trial name
- ELP (NCT04397068)
- Testing
- phaco-vitrectomy
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Macular Edema Following Cataract Surgery
Trientine Hydrochloride for the Prevention of Macular Edema After Cataract Surgery in Patients With Type 2 Diabetes Mellitus
The primary purpose of the protocol is to evaluate whether Trientine Hydrochloride, a copper chelator which is an agent that binds with and removes copper, will be effective in minimizing macular edema after cataract surgery in…
- Trial name
- NCT01295073
- Testing
- Trientine Hydrochloride, For Arm B there is no therapeutic intervention other than standard of care, which is cataract surgery.
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Diabetic Retinopathy, Proliferative Vitreoretinopathy
Molecular Taxonomy of Surgically-harvested Ocular Tissues Defined by Single-cell Transcriptomics
The surgically-harvested eye tissue (ie. vitreous-retinal proliferative membrane, outflow pathway, retinas, and pterygium) is a complex tissue responsible for maintaining intraocular homeostasis or mediating ocular pathogenesis.
- Conditions
- Diabetic Retinopathy, Proliferative Vitreoretinopathy, Pterygium, Glaucoma
- Trial name
- Eyesinglecell (NCT04682054)
- Testing
- ocular surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Vitreomacular Traction Maculopathy, Eye Diseases
Intravitreal Microplasmin in Patients Undergoing Surgical Vitrectomy
The purpose of this trial is to evaluate the safety and preliminary efficacy of different doses and several exposure times of intravitreal microplasmin in the setting of pars plana vitrectomy for vitreomacular traction…
- Trial name
- NCT00123279
- Testing
- Microplasmin
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 60 people
- Sponsor
- ThromboGenics