Clinical trials: Retina Surgery
Retinopathy
Anesthesia for Retinopathy of Prematurity
Premature infants experience more respiratory problems after surgical procedures. The investigators aimed to compare general anesthesia with sedation on the need for post-operative mechanical ventilation in infants undergoing…
- Trial name
- NCT01955135
- Testing
- Ketamine, Sevoflurane, propofol
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Wet Macular Degeneration, Cataract Extraction
Management of Patients With Neovascular Age-related Macular Degeneration Undergoing Cataract Surgery
To-date there have been only very few studies to examine the effect of cataract surgery to patients with wet age-related macular degeneration.
- Trial name
- NCT03944070
- Testing
- Ranibizumab
- Where
- Greece
- Volunteers
- 16 people
- Sponsor
- Ophthalmica Eye Institute
Retinal Detachment, Proliferative Vitreoretinopathy
Internal Limiting Membrane Peeling in Retinal Detachment Surgery
Despite advances in surgical techniques over the recent decades, proliferative vitreoretinopathy (PVR) remains the main obstacle to successful rhegmatogenous retinal detachment (RRD) repair, accounting for nearly 75% of all…
- Trial name
- IMPURITY (NCT05538156)
- Testing
- Control group, Intervention group
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Thyroid Carcinoma, Thyroid Nodule (Benign)
Function Integrity of Neck Anatomy in Thyroid Surgery
Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy.
- Conditions
- Thyroid Carcinoma, Thyroid Nodule (Benign), Ablation; Retina
- Trial name
- NCT04666103
- Testing
- Intraoperative thermal ablation
- Where
- China
- Volunteers
- 1,264 people
- Sponsor
- Wuhan University
Surgical Retinal
CD160 Expression in Retinal Vessels is Associated With Retinal Neovascular Diseases
The aims of this study were to analyze CD160 expression in both normal and pathological eyes from human adults to evaluate association between CD160 presence on endothelial cells from blood vessels and retinal vascular disease
- Trial name
- NEOVASC-CD160 (NCT03940664)
- Testing
- immunohistochemistry on Formalin fixed and paraffin embedded blocks
- Where
- France
- Volunteers
- 75 people
- Sponsor
- CHU de Reims
Retinal Detachment
Animated Video Education for Retinal Surgery
Retinal detachment is a vision-threatening condition that requires urgent surgical repair. Understanding the condition, the surgery, and post-operative instructions is difficult for many patients, particularly in multilingual and…
- Trial name
- NCT07184255
- Testing
- Patient Education Video Intervention
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Toronto
Epiretinal Membrane, Macular Edema
A Pilot Study of the Effectiveness of Intra-operative Ozurdex® in Vitrectomy Surgery for Epiretinal Membranes
To determine if an intravitreal sustained release dexamethasone implant (Ozurdex®) injected at the conclusion of surgery in patients undergoing vitrectomy and membrane peeling for idiopathic epiretinal membranes is safe and…
- Trial name
- NCT01701518
- Testing
- Ozurdex
- Where
- 2 sites in Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetes Mellitus, Diabetic Retinopathy
Retinal Adaptation to Intensified Insulin Therapy and Bariatric Surgery in Patients With Diabetes
Retinal function is highly dependent on the glucose supply. Thus, functional adaptations occur in response to both acute and long-term changes in glycaemia.
- Trial name
- NCT01517490
- Testing
- Insulin pump, Multiple daily insulin injections, Bariatric surgery
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema
The Effect of a Blue Light Filtering IOL
To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering…
- Conditions
- to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema, After Cataract Surgery
- Trial name
- NCT00571831
- Testing
- intraocular lens implantation
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Showa University
Epiretinal Membrane
Epiretinal Fibrosis, Effect of Early Surgery
The goal of this randomized clinical trial is to investigate when it is optimal to treat the eye disease epiretinal fibrosis. Hypothesis: In a population of patients with symptomatic idiopathic epiretinal fibrosis and visual…
- Trial name
- epitell (NCT00902629)
- Testing
- Early surgery
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Myocardial Revascularization Surgery With Extracorporeal Circulation
Retinal Microvascular Network and Coronary Revascularization Surgery at the Dijon University Hospital
When coronary artery disease cannot be treated with medication, revascularization surgery can be performed. Although there have been many advances in recent years, this surgery is still associated with a high incidence of…
- Trial name
- MRCC (NCT05315349)
- Testing
- Complete ophthalmological check-up, Blood sampling
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Macular Degeneration, Histoplasmosis
Submacular Surgery Trials (SST)
To determine whether surgical removal of subfoveal choroidal neovascularization (CNV) and associated hemorrhage in patients with age-related macular degeneration (AMD), the ocular histoplasmosis syndrome (OHS), or idiopathic CNV…
- Trial name
- NCT00000150
- Testing
- Subfoveal Choroidal Neovascularization Removal
- Sponsor
- National Eye Institute (NEI)
Macular Hole
Outcomes of Macular Hole Surgery With Inverted Flap With vs Without Post op Posturing With SF6 in Macular Hole More Than 400 Micrometres
This study evaluated the outcomes of surgery for large full-thickness macular holes measuring more than 400 micrometres using the inverted internal limiting membrane flap technique with sulphur hexafluoride (SF6) gas tamponade.
- Trial name
- NCT07787390
- Testing
- Macular Hole Surgery With Inverted Internal Limiting Membrane Flap and SF6 Gas Tamponade, Face-Down Postoperative Positioning, No Face-Down Postoperative Positioning
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore General Hospital
Macular Holes
Position Related Changes in Macular Hole Morphology Before and After Surgery
Macular hole is a full thickness retinal defect in the very centre of the retina that gives the sharpest vision. The condition causes a substantial deterioration of visual acuity, and operative measures are necessary in order to…
- Trial name
- NCT04676217
- Testing
- Postoperative positioning advice
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Diabetic Retinopathy, Diabetic Cataract
Pars Plana Vitrectomy Combined With Phacoemulsification Cataract Surgery in Phakic Diabetes Retinopathy Patients
Pars plana vitrectomy (PPV) is one of the most widely used surgical therapies to proliferative diabetic retinopathy in the world.
- Trial name
- NCT04729023
- Testing
- Pars plana vitrectomy combined with cataract surgery., Pars plana vitrectomy with subsequent cataract surgery.
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Diabetes Mellitus Type 2, Age Related Cataracts
Comparison of Retinal Perfusion Between Diabetic and Non-diabetic Patients With OCT Angiography After Cataract Surgery.
This study aims to compare the retinal perfusion between diabetic and non-diabetic patients with Optical Coherence Tomography（OCT） Angiography after cataract surgery, to thoroughly evaluate the retinal state of diabetics after…
- Trial name
- NCT03903965
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Rhegmatogenous Retinal Detachment
Perfluorocarbon Liquid vs. Posterior Retinotomy During Pars-plana Vitrectomy for Rhegmatogenous Retinal Detachment
Purpose To evaluate the outcomes of perfluorocarbon liquid (PFCL) versus posterior retinotomy (PR) during Pars plana vitrectomy (PPV) for Rhegmatogenous retinal detachment (RRD), focusing on anatomical success, visual acuity…
- Trial name
- NCT06919211
- Testing
- Perfluorocarbon Liquid vs. Posterior Retinotomy during Pars-plana Vitrectomy for The Surgical Repair of Rhegmatogenous Retinal Detachment
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Benha University
Primary Open Angle Glaucoma
Electroretinogram and Retinal Vascular Changes After Cataract Surgery
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
- Trial name
- NCT05871034
- Testing
- phacoemulsification
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Epiretinal Membrane, Internal Limiting Membrane Wrinkling
Fovea ERM After Fovea-sparing ILM Peeling
To report cases who had received previous fovea-sparing internal limiting peeling membrane and developed secondary fovea epiretinal membrane contraction
- Trial name
- NCT04445142
- Testing
- fovea-sparing internal limiting membrane peeling
- Where
- Taiwan
- Volunteers
- 3 people
- Sponsor
- Changhua Christian Hospital