Clinical trials: Retinal Artery Occlusion
Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion
Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye
Canadians fear loss of vision more than any other disability. Vision loss has an enormous impact on quality-of-life and is extremely costly from a societal and economic perspective.
- Conditions
- Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion, Branch Retinal Vein Occlusion, Central Retinal Vein Occlusion
- Trial name
- NCT01348633
- Where
- Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Retinal Artery Occlusion
Reconstruction of Pathological Changes of the Ophthalmic Artery in Patients With Retinal Artery Occlusion
Retinal artery occlusions (RAO) cause deterioration in visual acuity and visual fields. In computational fluid dynamics (CFD) studies [1] 10% of ascending emboli caused RAO, the residual 90% embolized into the cerebral arteries.
- Trial name
- NCT02679716
- Testing
- MRI of the cerebral arteries
- Where
- 2 sites in Austria
- Volunteers
- 30 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Retinal Artery Occlusion
Long-term Clinical Outcomes After Retinal Artery Occlusion
Retinal artery occlusion (RAO) is a rare but vision-threatening vascular disorder that is commonly caused by embolic events originating from the heart or carotid arteries.
- Trial name
- CVO-RAO (NCT07482228)
- Testing
- retinal artery occlusion
- Where
- South Korea
- Volunteers
- 15,000 people
- Sponsor
- Chonnam National University Hospital
Glaucoma, Glaucoma Suspect
Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study
The goal is to conduct a 5-year prospective, randomized controlled trial to test an innovative, community-based intervention using posterior and anterior fundus photography of the optic nerve and macula and intraocular eye…
- Conditions
- Glaucoma, Glaucoma Suspect, Diabetic Retinopathy, Ocular Hypertension
- Trial name
- NCT02390245
- Testing
- Free Eye Screenings, Enhanced Intervention, Usual Care
- Where
- United States
- Volunteers
- 906 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Retinal Vein Occlusion
Retinal Thrombosis and Atherosclerosis
The retinal vein occlusion (RVO) is the second most common retinal disease after diabetic retinopathy, and is a common cause of unilateral visual loss.
- Trial name
- HEART-VISION (NCT02257333)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Roma La Sapienza
Uveitis, Conjunctivitis
Ocular Manifestations in Rheumatic Diseases
This is a search strategy for determining the prevalence of ocular complications in inflammatory rheumatic diseases for the purposes of a meta analysis.
- Conditions
- Uveitis, Conjunctivitis, Keratoconjunctivitis Sicca, Xerophthalmia
- Trial name
- NCT03753893
- Testing
- No intervention used
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Arteriosclerosis
Evaluation of the Capacity of a Camera to Identify Signs of Arteriosclerosis in Retinal Arterioles
Arteriosclerosis is a degenerative and dysmetabolic disease of the arterial walls. It is known to be the principal cause of coronary artery disease (CAD).
- Trial name
- NCT02849405
- Testing
- MHRC: Metabolic Hyperspectral Retinal Camera
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jean-Claude Tardif
Retinal Vascular Occlusion
Obstructive Sleep Apnea, Retinal Vein Occlusion, Retinal Artery Occlusion
Obstructive sleep apnea is a common disorder linked to serious long-term adverse health consequences; such as hypertension, metabolic dysfunction, cardiovascular disease.
- Trial name
- NCT01291862
- Testing
- Watchpat 100
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Intracranial Atherosclerosis
ICAS Screen Based on RIC
Intracranial atherosclerosis stenosis (ICAS) is a leading cause of ischemic stroke worldwide and increase the global burden of stroke, especially in the Asian population.
- Trial name
- RICAS (NCT06610578)
- Testing
- fundus imaging
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Susac Syndrome
Investigation of Biomarkers in Susac Syndrome
Susac Syndrome is a rare disease and the establishment of the diagnosis is often difficult. The aim of this investigation is to identify relevant biomarkers and to elucidate the pathogenesis of Susac syndrome
- Trial name
- NCT01273792
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Central Retinal Artery Occlusion, Visual Field
Changes of Visual Field Defects After IAT for CRAO
Central retinal artery occlusion (CRAO) is an ophthalmic emergency which leads to devastating visual function defects and poor prognosis.
- Conditions
- Central Retinal Artery Occlusion, Visual Field, Intra-arterial Thrombolysis
- Trial name
- NCT05739487
- Testing
- selective intra-arterial thrombolysis
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Age-related Macular Degeneration, Coronary Artery Disease
Age-related Macular Degeneration (AMD) and Cardiovascular Disease
The purpose of this research study is to investigate the link between age-related macular degeneration (AMD or ARMD) and coronary artery disease (CAD).
- Conditions
- Age-related Macular Degeneration, Coronary Artery Disease, Cardiovascular Diseases
- Trial name
- NCT04087356
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The New York Eye & Ear Infirmary
Choroid Disease, Carotid Stenosis
Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis
The retinal vessels have been shown to reflect vascular changes inherent to systemic pathologies, even when no ocular disease is identified.
- Conditions
- Choroid Disease, Carotid Stenosis, Carotid Atherosclerosis, Retinal Disease
- Trial name
- NCT05623293
- Testing
- eye - Optcial coherence tomography
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Universidade do Porto
Central Retinal Artery Occlusion
Study of Arterial Recanalization of the Central Retinal Artery Occlusions
Central retinal artery occlusions (CRAO) are the equivalent of an ischemic stroke (IS) at the retinal level. They share the same risk factors and common pathology.
- Trial name
- RECANAL (NCT03049514)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Atherosclerosis, Cardiovascular Diseases
Multi-Ethnic Study of Atherosclerosis (MESA) - Ancillary Eye Study
To evaluate the relation of retinal microvascular characteristics to subclinical cardiovascular disease, clinical disease, and their risk factors in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease
- Trial name
- MESA-Eye (NCT00041444)
- Volunteers
- 6,176 people
- Sponsor
- University of Wisconsin, Madison
Central Retinal Artery Occlusion
The Effect of Transcorneal Stimulation in Cases of Central Retinal Artery Occlusion Using a New Waveform
The purpose of this study is to describe the effect of transcorneal electrical stimulation (TES) with a non conventional biphasic bipolar waveform in central retinal artery occlusion
- Trial name
- NCT00802698
- Testing
- Transcorneal electric stimulation, Transcorneal stimulation
- Where
- Mexico
- Volunteers
- 5 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Central Retinal Artery Occlusion
TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS)
TENecteplase in Central Retinal Artery Occlusion (TenCRAOS): A Prospective, randomized-controlled, double-dummy, double-blind phase 3 multi-centre trial of TNK 0.25 mg/kg + placebo vs.
- Trial name
- TenCRAOS (NCT04526951)
- Where
- 18 sites in Belgium, Denmark and 4 more
- Volunteers
- 81 people
- Sponsor
- Oslo University Hospital
Retinal Artery Occlusion
Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion
Purpose of the study is to examine the retinal blood flow in chronic cases of retinal artery occlusion with non-invasive, non-contact optical coherence tomography angiography.
- Trial name
- RAO-OCTA (NCT03357146)
- Testing
- Optical coherence tomography angiography
- Where
- Hungary
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Diabetes Mellitus Type 2
Patients With Type 2 Diabetes
Diabetes mellitus
- Trial name
- NCT07245082
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Coronary Artery Disease
Optina Eye to Heart Connection
This is a prospective cross-sectional, single-center retinal imaging study expecting to enroll approximately 400 male and female subjects ≥ 18 years of age.
- Trial name
- NCT05199428
- Where
- Canada
- Volunteers
- 308 people
- Sponsor
- Optina Diagnostics Inc.