Clinical trials: Retinal Blood Vessels
Preeclampsia (PE), Hypertension ,Pregnancy
Retinal and Choroidal Microcirculation in Preeclampsia: An OCTA Study
Preeclampsia is a multisystemic and multifactorial disorder that complicates pregnancy and is characterized by new-onset hypertension after the 20th week of gestation accompanied by proteinuria or systemic findings such as renal…
- Conditions
- Preeclampsia (PE), Hypertension ,Pregnancy, Retinal Microvascular Changes, Hypertensive Disorders of Pregnancy
- Trial name
- PE-OCTA (NCT07874191)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Diabetes Mellitus, Type 1, Diabetic Retinopathy
Choroidal Blood Flow Changes During Dark/Light Transitions in Patients With Insulin-dependent Diabetes Mellitus (IDDM)
There is evidence from a variety of animal studies that choroidal blood flow is under neural control. Recent results in humans indicate that a light/dark transition is associated with a short lasting reduction in choroidal blood…
- Trial name
- NCT00718614
- Testing
- Light will be switched from 0.5µW/cm2/sr to 115µW/cm2/sr.
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Retinal Vein Occlusion
Ranibizumab in Patients With Branch Retinal Vein Occlusion
In a recent study we could show that the early retinal venous vasoconstriction after grid photocoagulation in branch retinal vein occlusion (BRVO) is closely correlated to the visual outcome after three months.
- Trial name
- NCT01027481
- Testing
- Lucentis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Glaucoma
Retinal Vascular Reactivity in Subjects With Newly Diagnosed Glaucoma Before and After Selective Laser Trabeculoplasty
The purpose of this study is to assess retinal blood flow and vascular reactivity in patients with newly diagnosed primary open angle glaucoma pre- and post-primary Selective Laser Trabeculoplasty(SLT).
- Trial name
- NCT01209975
- Testing
- Selective Laser Trabeculoplasty
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Toronto
Retinal Blood Vessels, Age-Related Macular Degeneration
Multimodal Imaging of Retinal Vessels
Retinal blood flow measurement is of scientific and clinical value. For this purpose retinal vessel morphology (such as diameter, vessel wall thickness, etc) determination is crucial.
- Trial name
- MIR (NCT02717026)
- Testing
- Optical coherence tomography, Fluorescein angiography, Fundus photography
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
Cardiovascular Disease, Childhood Obesity
Exercise and Arterial Modulation in Youth
The project is designed as a large scale, cross-sectional study. The aim of the study is to investigate the association of micro- and macrovascular function with physical fitness and body composition in primary school children.
- Conditions
- Cardiovascular Disease, Childhood Obesity, Hypertension, Endothelial Dysfunction
- Trial name
- ExAMIN YOUTH (NCT02853747)
- Testing
- Physical Activity, 20-meter shuttle run
- Where
- Switzerland
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- University of Basel
Retinal Vascular
Chocolate Dynamic Vessel Analysis
The study aims at evaluating the effect of dark chocolate consumption on anatomy and functionality of retinal blood vessels by comparing these same parameters after milk chocolate consumption.
- Trial name
- NCT05227248
- Testing
- Dark chocolate, Milk Chocolate
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Querques Giuseppe
Adolescent, Adult
Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation
To observe the retinal microvascular alteration during 3 months follow-up after Implantable Collamer Lens (ICL) operation in moderate and high myopia patients using quantitative optical coherence tomography angiography (OCTA)…
- Conditions
- Adolescent, Adult, Human, Male
- Trial name
- NCT04443231
- Testing
- Optical Coherence Tomography Angiography
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Pregnancy, High Risk Pregnancies
DVA Risk Pregnancy
Maternal obesity, overweight and hypertensive disorders are among the most important risk factors for complications during pregnancy.
- Trial name
- NCT02340442
- Testing
- Obstetrical care parameters, DVA measurements, Fundus photographs
- Where
- 2 sites in Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Arterial Hypertension, Blood Pressure, High
Effects of Change in Blood Pressure on Retinal Capillary Rarefaction in Patients With Arterial Hypertension
To evaluate whether in patients with initially poorly-controlled arterial hypertension, structural and functional differences in the retina and choroid remain after achieving a well-controlled blood pressure.
- Trial name
- NCT06098300
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Diabetic Retinopathy, Neurodegeneration
Glycemic Control and Retinal Microvascular Changes
The goal of this prospective, observational study is to compare in the association of glycemic control and retinal microvascular changes in patients with type 2 diabetes mellitus (T2DM) without diabetic retinopathy (DR).
- Conditions
- Diabetic Retinopathy, Neurodegeneration, Blood Sugar; High
- Trial name
- NCT06150495
- Where
- South Korea
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chronic Coronary Syndrome, Heart Failure
COVID-19 Related Lockdown Effects On Chronic Diseases
The containment associated with the VIDOC-19 pandemic creates an unprecedented societal situation of physical and social isolation.
- Conditions
- Chronic Coronary Syndrome, Heart Failure, AMD and Macular Edema, Chronic Respiratory Failure
- Trial name
- CLEO-CD (NCT04390126)
- Testing
- life questionnaires, questionnaire
- Where
- France
- Volunteers
- 1,343 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Healthy Participants
The Effects of Strength Training Volume, Intensity, and Breathing Techniques on Intraocular Pressure and Retinal Blood Vessels
This study aims to determine the effects of different breathing patterns on ocular vasculature and intraocular pressure (IOP) during isokinetic and isometric strength exercises.
- Trial name
- NCT07326462
- Testing
- Normal Breathing, Valsalva maneuver
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Type 1 Diabetes Mellitus
Endothelial Dysfunction and Diabetes
The aim of the study is to progress in the understanding of the early retinal vascular and neural abnormalities in patients with diabetes, using a new device, the Dynamic Vessel Analyzer.
- Trial name
- DENDI (NCT01097551)
- Testing
- Trinitrin, Neosynephrine 10% collyrium, Iontophoresis with acetylcholine delivery
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Eye Diseases, Ophthalmic Trauma
Mitochondrial DNA in Vitreous Fluid and Blood in Patients With Eye Disease or Ocular Trauma.
This study is to characterize mitochondrial DNA (mtDNA) populations in adults with eye injuries and eye diseases. The eye exam is often hindered by the clouding of tissues involved in injury or disease.
- Conditions
- Eye Diseases, Ophthalmic Trauma, Mitochondrial DNA, Age Related Macular Degeneration
- Trial name
- NCT04334499
- Testing
- Sample collection from tissue discard
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cardiovascular Diseases, Childhood Obesity
Sportcheck Follow-Up
The study resembles a four-year follow-up on the influence of physical activity and fitness, blood pressure, BMI and stress on vascular health in primary schoolchildren.
- Conditions
- Cardiovascular Diseases, Childhood Obesity, Hypertension
- Trial name
- NCT03085498
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Basel
Type I Diabetes
Measurement of Total Retinal Blood Flow in Patients With Diabetes and Healthy Subjects
The prevalence of diabetes and diabetes-associated complications is still increasing. Several major long-term complications of diabetes such as cardiovascular disease, chronic renal failure, diabetic retinopathy and others relate…
- Trial name
- NCT01843114
- Testing
- FDOCT, Dynamic Vessel Analyzer
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cardiovascular Disease, Obesity
Exercise, Arterial Cross-Talk Modulation and Inflammation in an Ageing Population
The aims of the study are twofold. In the cross-sectional approach (Part I), the study will be conducted in an older population to assess the association of physical fitness on different parts of the human vascular bed.
- Conditions
- Cardiovascular Disease, Obesity, Atherosclerosis, Heart; Disease, Activity
- Trial name
- ExAMIN AGE (NCT02796976)
- Testing
- Training or control condition
- Where
- Switzerland
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Basel
Hypertension
Target Organ Damage and Polymorphisms Vav-2 and Vav-3 in Hypertensive Subjects
Objectives: To analyze the influence on the presence of target organ damage renal, cardiac and vascular of peripheral and central blood pressure, retinal vessels caliber, oxidative stress and polymorphisms of genes VAV-2-3 in…
- Trial name
- LOD-HTA (NCT02022618)
- Where
- Spain
- Volunteers
- 454 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Age-Related Macular Degeneration, Choroidal Vessels; Anastomosis
Evaluation of Optical Coherence Tomography.
Determination of the sensitivity and specificity of different combinations of imaging techniques (spectral domain optical coherence tomography, fundus photography and fluorescein angiography) used for the diagnosis of choroidal…
- Trial name
- ESSO (NCT01080898)
- Testing
- tests
- Volunteers
- 151 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris