Clinical trials: Retinal Blood Vessels
Telangiectasia
Injected Ranibizumab to Treat Macular Telangiectasia With New Blood Vessel Formation
This study will examine whether the drug ranibizumab is an effective treatment for macular telangiectasia, a condition in which existing blood vessels near the macula (the back part of the eye responsible for sharp central…
- Trial name
- NCT00457067
- Testing
- Ranibizumab
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Hypertension, Retinal Disorder
DETECT and Retinal Outcomes in Hypertension
The purpose of this study is to study the impact of blood pressure on cognitive performance.
- Conditions
- Hypertension, Retinal Disorder, Cognitive Impairment
- Trial name
- NCT01815567
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Emory University
Diabetic Macular Edema
Vitrectomy Retinal Oxygenation
Vitrectomy is the common treatment for patients with macular edema secondary to epiretinal membrane. Recently, in eyes with diabetic macular edema or persistent macular edema following retinal vein occlusion, vitrectomy will be…
- Trial name
- NCT01510691
- Where
- Austria
- Sponsor
- Stefan Sacu
Fabry Disease, Endothelial Dysfunction
Characterizing the Retinal Microvasculature in Patients with Fabry Disease: a Prospective Observational Study
This study aims to gain a deeper understanding of endothelial dysfunction in patients with Fabry disease through a prospective study of the retinal microvasculature and to identify an objective, non-invasive marker to assess…
- Conditions
- Fabry Disease, Endothelial Dysfunction, Microvasculature
- Trial name
- VASCinFABRY (NCT06758648)
- Testing
- Dynamic retinal vessel analysis (DVA), Biochemistry and immune phenotyping, Questionnaires (Patient reported outcomes)
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Technical University of Munich
Coronary Vasospasm
Effect of Glucose on Ocular Blood Flow
The primary objective is to assess the effect of glucose on retinal vascular diameter in otherwise healthy vasospastic subjects compared to non-vasospastic controls.
- Trial name
- NCT00350129
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Open-Angle Glaucoma
Influence of Prostaglandins on Ocular Blood Flow in Glaucoma Patients
Vasoactivity of topical drugs may be of prognostic relevance in glaucoma. There is very little information for a major class, the prostaglandin analogues with regard to this aspect.
- Trial name
- NCT00308945
- Testing
- travoprost 0.004% (drug), latanoprost 0.005% (drug)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiovascular Risk Factor
Automatic Image Analyzer to Assess Retinal Vessel Caliber
The objective of this work is the development and validation (reliability and validity) of the Automatic image analyzer to assess it retinal vessel caliber (ALTAIR) platform to analyze and validate its utility in different…
- Trial name
- ALTAIR (NCT02087605)
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Retinopathy of Prematurity
Heredity of Retinal Vessel Tortuosity
The purpose of this study is to asses the relative influence of genetic and environmental influence on the tortuosity of retinal arterioles in eyes of 218 healthy Danish twins aged 20-46 years.
- Trial name
- NCT00427063
- Where
- Denmark
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Eye Diseases, Retina; Lesion
Comparison of Non-mydriatic Camera Systems in a Female Health Hospital
1. To compare quality and usability of images taken by two different camera-systems without dilating the pupil. 2. To compare the retinal vessel diameters based on the images of to different camera-systems. 3.
- Conditions
- Eye Diseases, Retina; Lesion, Optic Disc Structural Anomaly
- Trial name
- NCT02089009
- Testing
- Retinal imaging, Vessel measurements, Change in vessel diameters
- Where
- 2 sites in Germany
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Dr. Martin Leitritz
Smokers
Effect of Smoking on Retinal Vessel Morphology and Functionality
The study aims at evaluating the effect of smoking activity on anatomy and functionality of retinal blood vessels using optical coherence tomography angiography (OCT-A) and dynamic vessel analysis (DVA).
- Trial name
- NCT07261176
- Testing
- Cigarette Smoking
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Child, Motor Activity
CHAMPS Eye Study - Myopia and Retinal Vascular Geometry in Relation to Physical Activity
An increasingly physical inactive lifestyle in the Western World has led to a higher number of lifestyle -related diseases. The consequences are now already present in childhood with an increased prevalence of overweight…
- Conditions
- Child, Motor Activity, Myopia
- Trial name
- NCT02346006
- Testing
- More physical activity.
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Diabetic Retinopathy
Coupling of Neural Activity and Retinal Blood Flow in Diabetes
The prevalence of diabetes is increasing and the management of the disease is nowadays considered a major challenge. Affected patients have increased mortality and morbidity as well as a significant drop in the quality of life.
- Trial name
- NCT01375166
- Where
- Austria
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Macular Degeneration
Identification and Treatment of Feeder Vessels in Macular Degeneration
This study will try to identify and treat feeder vessels in age-related macular degeneration. The macula is the part of the retina in the back of the eye that determines central or best vision.
- Trial name
- NCT00018070
- Testing
- Angiography, Laser Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Eye Institute (NEI)
HCV Infection
Role OF OCT-A TO Detect Possible Retinal Vascular Complications of Sofosbuvir in Patients With Hepatitis C
The purpose of this study is to prospectively evaluate the value of Optical coherence tomography angiography (OCT-A) for the of detection of suspected retinal complications With Sofosbuvir (Sovaldi) in Patients With Hepatitis C…
- Trial name
- NCT04159246
- Testing
- Optical coherence tomography angiography, Sofosbuvir (Sovaldi)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mohamed Saad
Diabetic Retinopathy
Blood Factors and Diabetic Retinopathy
This study will determine whether certain factors in the blood are associated with the severity of diabetic retinopathy. Patients age 10 years and older with diabetes mellitus and diabetic retinopathy may be eligible for this…
- Trial name
- NCT00005761
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- National Eye Institute (NEI)