Clinical trials: Retinal Detachment Rhegmatogenous
Rhegmatogenous Retinal Detachment, Surgery
Treating Rhegmatogenous Retinal Detachment by Foldable Capsular Buckle
To evaluate the efficacy and safety of treating rhegmatogenous retinal detachment (RRD) using foldable capsular buckle (FCB). It is a multi-center clinical ,randomized, controlled, and single-blind clinical study.
- Trial name
- NCT04571788
- Testing
- Foldable Capsular Buckle, Silicone scleral padding
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Proliferative Vitreoretinopathy
Methotrexate For The Prevention and Treatment of Proliferative Vitreoretinopathy in Pediatric Patients
Rhegmatogenous retinal detachment (RRD) is a sight-threatening condition. Children with RRD usually present late with clinical features of longstanding RRD, specifically a serious condition named: proliferative vitreoretinopathy…
- Trial name
- SIGHT (NCT04830878)
- Testing
- Methotrexate
- Where
- United States
- Sponsor
- Stanford University
Retinal Detachment, Full Thickness Macular Hole
Inflammasomes in Cell Death in FTMH, ERM, and RRD
Prospective study evaluating the role of inflammasomes in cell death in retinal detachment, full thickness macular hole, and epiretinal membrane.
- Conditions
- Retinal Detachment, Full Thickness Macular Hole, Epiretinal Membrane
- Trial name
- NCT03332758
- Testing
- Pars plana vitrectomy, External drainage
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Allen C. Ho, MD
Retinal Detachment
Scleral Self-indentation Chandelier-assisted Peripheral Vitrectomy Under Air Rhegmatogenous Retinal Detachment.
The investigators compared the incidence of trimming-induced retinal breaks, retinal redetachment rate, and final LogMAR BCVA; between scleral self-indentation and non-indentation during chandelier-assisted peripheral vitrectomy…
- Trial name
- NCT03218371
- Testing
- chandelier-assisted peripheral vitrectomy under air
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Dar El Oyoun Hospital
Rhegmatogenous Macula-off Retinal Detachment
Safety and Efficacy of Brimonidine Tartrate Posterior Segment Drug Delivery System in Improving Visual Function
This study will evaluate the efficacy and safety of the Brimo PS DDS® Applicator System (200 μg and 400 μg brimonidine tartrate) on visual function in patients with previous rhegmatogenous macula-off retinal detachment.
- Trial name
- NCT00972374
- Testing
- 400 ug Brimonidine Implant, 200 ug Brimonidine Implant
- Where
- 6 sites in United States, India and 4 more
- Volunteers
- 44 people
- Sponsor
- Allergan
Rhegmatogenous Retinal Detachment
Comparative Study Between Three Different Techniques in Drainage of SRF During PPV in RRD
The study will investigate and compare the three techniques in drainage of subretinal fluid in patients with macula off RRD: namely using the original break, performing a posterior drainage retinotomy and using PFC with drainage…
- Trial name
- NCT06324305
- Testing
- Pars plana vitrectomy (PPV) and drainage of subretinal fluid
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Retinal Detachment, Vitrectomy
Functional and Morphological Results of Rhegmatogenous Retinal Detachment Treated With Vitrectomy
To examine morphological and functional results after pars plana vitrectomy (PPV) with SF6 gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during six months of the follow-up.
- Trial name
- NCT03902795
- Testing
- Microperimetry, M-charts
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Medical University of Lublin
Rhegmatogenous Retinal Detachment
Retinal Detachment - Demographic and Clinical Survey
Background: Rhegmatogenous retinal detachment is an ophthalmic emergency that, without surgical repair, often leads to blindness. The incidence is about 1/10000/year.
- Trial name
- NCT01845571
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Retinal Detachment Rhegmatogenous, ILM Peeling
1ry Versus 2ry ILM Peeling in RD
Patients with uncomplicated rhegmatogenous retinal detachment will be recruited. All eyes will underwent 23G PPV with silicon oil tamponade. The eyes will be classified into two groups according to the timing of ILM peeling.
- Trial name
- NCT07346560
- Testing
- Primary ILM peeling, Secondary ILM peeling
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Rhegmatogenous Retinal Detachment
hAM for Inferior RRD
The objective of the study is to evaluate the efficacy of using hAM patches over the retina to seal inferior retinal breaks. The researchers will evaluate whether hAM patch-assisted vitrectomy improves surgical success rate of…
- Trial name
- NCT07081945
- Testing
- hAM
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Epiretinal Membrane, Macular Hole
UNITY VCS Vitreoretinal Surgery
This purpose of this study is to compare the safety and effectiveness of two eye surgery systems-UNITY VCS and CONSTELLATION-in treating adults with vitreoretinal diseases or disorders.
- Conditions
- Epiretinal Membrane, Macular Hole, Visually Significant Vitreous Floater, Vitreomacular Traction
- Trial name
- NCT07054281
- Testing
- UNITY Vitreoretinal Cataract System (VCS), CONSTELLATION Vision System, Vitreoretinal ophthalmic surgery
- Where
- 8 sites in United States
- Sponsor
- Alcon Research
Rhegmatogenous Retinal Detachment
Axial Length Change in Eyes Treated by Silicone Sponge Scleral Buckling
All existing medical literatue regarding axial length (AL) changes after scleral buckling surgery for retinal detachment, descibes changes after solid silicone buckling.
- Trial name
- NCT01647373
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Traction Retinal Detachments, Rhegmatogenous Retinal Detachments
Vitreous Surgery With Intraocular Assistance
To Assess the Safety of Vitreous surgery with intraocular assistance (VISIA) \& to identify and document with video evidence and surgeon's case report forms intraocular maneuvers that are facilitated by VISIA.
- Conditions
- Traction Retinal Detachments, Rhegmatogenous Retinal Detachments, Dislocated Intraocular Lens
- Trial name
- VISIA (NCT02574624)
- Testing
- Intraocular assistance
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Vitreoretinopathy, Coats' Disease
DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia
The Tender Study is a prospective, open-label, single-center, randomized, investigator-initiated clinical study seeks to investigate the safety and efficacy of the DEXTENZA insert in pediatric patients following retinal surgery…
- Conditions
- Vitreoretinopathy, Coats' Disease, Exudative Retinopathy, Lattice Degeneration
- Trial name
- NCT05620901
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Pred Forte
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lejla Vajzovic, MD, FASRS
Rhegmatogenous Retinal Detachment
Treatment of Retinal Detachment in People Who Have Not Had Cataract Surgery With Vitrectomy vs Vitrectomy and Cataract Removal
Background and study aims The retina is the layer at the back of the eye that allows us to see. Sometimes, it can detach from the wall of the eye, causing a condition called rhegmatogenous retinal detachment (RRD), which leads to…
- Trial name
- COMBAT (NCT06997874)
- Testing
- Phacovitrectomy, Vitrectomy
- Where
- 30 sites in United Kingdom
- Volunteers
- 276 people
- Sponsor
- Queen's University, Belfast
Retinal Displacement After Retinal Detachment Surgery
Influence of Perfluorocarbon Liquid (LIQUID) During Pars Plana Vitrectomy on Retinal Vessel Displacement in Primary Macula-involving Rhegmatogenous Retinal Detachment
Rhegmatogenous retinal detachment (RRD) is an acute, sight threatening condition, with an incidence of approximately 10 per 100,000 people.
- Trial name
- LIQUID (NCT07027098)
- Testing
- Perflurocarbon liquid, Without Perflurocarbon liquid
- Where
- United Kingdom
- Volunteers
- 292 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Rhegmatogenous Retinal Detachment
Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation
The purpose of this randomized clinical trial was to compare reattachment rates among patients with rhegmatogenous retinal detachment who underwent scleral buckle surgery with retinopexy by cryotherapy versus postoperative (one…
- Trial name
- NCT01068379
- Testing
- criopexy, laser
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Retinal Detachment Rhegmatogenous, Vitrectomy
Influence of Tamponade on Retinal Shift in Eyes Undergoing Vitrectomy for Rhegmatogenous Retinal Detachment: A Comparison of Gas Versus Silicone Oil in a Pakistani Population
Rhegmatogenous retinal detachment (RRD) is a vision-threatening condition with an estimated incidence of approximately 1 in 10,000 individuals annually.
- Conditions
- Retinal Detachment Rhegmatogenous, Vitrectomy, Retina Disorder
- Trial name
- TARS (NCT07495319)
- Testing
- Pars plana vitrectomy
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Wardah
Retinal Detachment
Evolution of Aqueous Flare in Rhegmatogenous Retinal Detachments Treated With Gas or Silicone Oil Tamponade.
To examine and to compare the evolution of aqueous flare from presentation until the third postoperative month in a series of consecutive patients who underwent primary vitrectomy for rhegmatogenous retinal detachment (RRD), in 4…
- Trial name
- FLADESIL (NCT05053698)
- Testing
- Aqueous flare measurement
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Central Hospital, Nancy, France
Retinal Detachment With Break
Suprachoroidal Visco-buckling for the Treatment of Rhegmatogenous Retinal Detachment
The study compares standard surgery for retinal detachment (RD) (vitrectomy, cryotherapy and gas) with a surgical variation that replaces the intraocular gas tamponade with suprachoroidal injection of viscoelastic underneath the…
- Trial name
- VIKING (NCT04557527)
- Testing
- Pars plana vitrectomy, laser or cryo retinopexy and intraocular gas tamponade, Suprachoroidal viscobuckle with 2.3% Sodium hyaluronate (Healon 5 Ophthalmic viscoelastic device)
- Where
- 6 sites in United Kingdom
- Volunteers
- 36 people
- Sponsor
- King's College Hospital NHS Trust