Clinical trials: Retinal Disease, Electroretinogram
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Retinal Function in Diabetic Patients Without Retinopathy
The primary purpose was to assess, in diabetic patients without diabetic retinopathy and control subjects, color vision, contrast sensitivity, electroretinography, and flicker-induced vasodilatation using the Dynamic Vessel…
- Trial name
- NEURODIAB (NCT00839150)
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Macular Edema
Comparison of the Effects of Bevacizumab Before vs After Pattern Panretinal Photocoagulation
Compare the effect of an intravitreal injection of bevacizumab previous or posterior of panretinal laser photocoagulation (PRLP) with a pattern laser; to prevent and reduce diabetic macular edema (DME) in patients with…
- Trial name
- NCT00804206
- Testing
- bevacizumab
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Glaucoma
Effects of Palmitoylethanolamide on Inner Retinal Function in Glaucoma Patients by Pattern Electroretinogram
The general purpose of the study is to evaluate the potential beneficial effects of PEA 600 mg supplementation on RGCs function in subjects with glaucoma by pattern electroretinogram after three months of therapy.
- Trial name
- NCT04088084
- Testing
- palmitoylethanolamide (PEA) 600 mg
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Rheumatoid Arthritis
Cross-over Study to Investigate Retinal Function Following Administration of a Single Dose of AZD9056
The purpose of the study is to determine whether treatment with a single 800mg dose of AZD9056, a medication which has been developed as a possible treatment for Rheumatoid Arthritis, has an effect on the function of the retina
- Trial name
- NCT00700986
- Testing
- AZD9056
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Age-related Macular Degeneration
Changes in Retinal Function After Intravitreal Ranibizumab for Age-related Macular Degeneration
Age-related macular degeneration, a leading cause of blindness, is caused by an abnormal growth of the vessels beneath the retina.
- Trial name
- NCT00539734
- Testing
- ranibizumab
- Where
- Thailand
- Volunteers
- 25 people
- Sponsor
- Prince of Songkla University
Myopia
Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate
The goal of this clinical trial is to compare pharmacological and non-pharmacological treatment effects on the children with different predicted myopia progression rate measured by modified multifocal electroretinogram.
- Trial name
- NCT06282848
- Testing
- Atropine 0.05%, DIMS lens
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Retinal Disease, Electroretinogram
RETeval All Comers Trial (REACT)
The primary objective of this study is to collect electroretinogram ERG measurements from visually normal and abnormal subjects using the FDA cleared RETeval device (K142567).
- Trial name
- REACT (NCT03065881)
- Testing
- RETeval
- Where
- United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- LKC Technologies, Inc.
Glaucoma
Relationship Between Eye Pressure and Ganglion Cell Function in Eyes Receiving Latanoprost Versus Placebo
The purpose of this investigation is to evaluate the relationship between IOP fluctuation, RGC dysfunction, and optic nerve and retinal nerve fiber layer (RNFL) thickness changes in patients with glaucoma and ocular hypertension…
- Trial name
- NCT01042665
- Testing
- latanoprost 0.005%
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Miami
Healthy, Macular Edema
Fundus Image-guided Focal Electroretinography, Usability Study
The purpose of this study is to investigate the usability of fundus image-guided focal electroretinography device with healthy subjects and with macular edema and macular degeneration patients.
- Conditions
- Healthy, Macular Edema, Macular Degeneration
- Trial name
- NCT05100511
- Testing
- ERG electrode tests for fundus image-guided focal ERG, Fundus image-guided focal ERG
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maculaser Oy
Non Proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy
Changes in Electroretinogram and Contrast Sensitivity After PASCAL Treatment
Laser photocoagulation has become the treatment of choice in PDR. Laser photocoagulation has become the treatment of choice in PDR.
- Trial name
- NCT00563043
- Testing
- PASCAL laser treatment
- Where
- Mexico
- Volunteers
- 8 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Retinitis Pigmentosa, X-linked Genetic Diseases
DHA and X-Linked Retinitis Pigmentosa
Purpose: Retinitis pigmentosa (RP) is characterized by progressive loss of visual function due to specific genetic mutations. This trial is focused on patients with one of the most severe forms of the disease, X-linked inherited…
- Trial name
- NCT00100230
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Retina Foundation of the Southwest
Age-related Macular Degeneration
CAPTAIN:Choroidal Neovascularization Assessment by Pattern Electroretinography
CNV from AMD is the leading cause of blindness in people over 50 in North America. The hypothesis is to determine if there is an improvement in retinal function determined by ERG following treatment with ranibizumab for AMD
- Trial name
- CAPTAIN (NCT00500344)
- Testing
- Lucentis (ranibizumab)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Fasting, Intermittent, Fasting Hypoglycemia
Electrophysiological Changes With Diet.
Dietary habits may affect our body by certain mechanisms, visual sense is one of the most vital human senses that needs special attention in our daily habits.
- Conditions
- Fasting, Intermittent, Fasting Hypoglycemia, Fasting, Obesity
- Trial name
- NCT05658991
- Testing
- Retinal electrophysiology
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Benha University
Preterm Birth, Retinopathy of Prematurity
Vitamin A and Very Low Birthweight Babies (VitAL)
Vitamin A is important for the development of healthy eyes and lungs. Very low birth weight premature babies have low body stores of vitamin A and are prone to diseases of the eye and lungs.
- Trial name
- NCT00417404
- Testing
- Aquasol A
- Where
- 2 sites in United Kingdom
- Volunteers
- 94 people
- Sponsor
- Glasgow Royal Infirmary
Retinal Disease, Visual Impairment
Repeatability of Electroretinogram and Visual Evoked Potential
To assess repeatability of electroretinogram and visual evoked potential in clinical practice
- Conditions
- Retinal Disease, Visual Impairment, Vision Disorders
- Trial name
- NCT05334875
- Testing
- Electroretinogram (ERG), Visual evoked potential (VEP)
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Benha University
Retinal Degeneration, Genetic Disease
Saffron Supplementation in Stargardt's Disease
The general area of research in which this project has been designed is that of retinal degeneration related to mutations in the ABCR gene, responsible of Stargardt disease/fundus flavimaculatus retinal dystrophy (STD/FF).
- Conditions
- Retinal Degeneration, Genetic Disease, Single-Gene Defects, Macular Dystrophy
- Trial name
- STARSAF02 (NCT01278277)
- Testing
- Saffron supplementation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Catholic University of the Sacred Heart
Diabetic Retinopathy
Levodopa for Diabetic Retinopathy
The purpose of this study is to determine optimum dosing strategies of levodopa and determine the physiologic mechanisms that provide the therapeutic response to restore abnormalities in the electrical conductivity of the retina…
- Trial name
- NCT07444892
- Testing
- Levodopa
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Emory University
Age Related Macular Degeneration
Study of Photobiomodulation Effect on Electroretinogram Outcomes in Dry Age-Related Macular Degeneration
To evaluate the ability of Photobiomodulation (PBM) treatment using the Valeda® Light Delivery System to improve Electroretinogram (ERG) outcomes in subjects with dry Age-related Macular Degeneration (AMD).
- Trial name
- ELECTROLIGHT (NCT04522999)
- Testing
- Photobiomodulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- LumiThera, Inc.
Bipolar Disorder
Study of Bipolar Disorders and Retinal Electrophysiological Markers
The BIMAR study aims to compare electrophysiological data measured with electroretinogram (ERG) and electroencephalogram (EEG) between a group of euthymic patients with bipolar disorder (BD) and a group of healthy controls…
- Trial name
- BIMAR (NCT05161546)
- Testing
- EEG and ERG measurements (Retinaute®, BioSerenity), Actigraphy (Motion Watch 8®, CamNtech), Neuropsychological assessments
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Retinopathy
Study of Stimulus Parameters in Flicker Electroretinogram (ERG)
The electroretinogram (ERG) is a diagnostic test that measures the electrical activity generated by cells in the retina in response to a light stimulus. Typically, an ERG is recorded with white flash when the pupil is dilated.
- Trial name
- NCT02466607
- Testing
- RETeval color flicker ERG, RETeval dilated versus un-dilated flicker ERG, pupil dilation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- LKC Technologies, Inc.