Clinical trials: Retinal Microcirculation Disorder, active
Pathologic Myopia
LED Red Light in Modulating Choroidal Microcirculation to Retard Retinal Atrophy in Pathological Myopia
The goal of this clinical trial is to learn if LED repeated low-level red light (RLRL) therapy works to treat pathologic myopia in adults. It will also learn about the safety of LED-RLRL.
- Trial name
- NCT07312214
- Testing
- LED red light
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Preeclampsia (PE), Hypertension ,Pregnancy
Retinal and Choroidal Microcirculation in Preeclampsia: An OCTA Study
Preeclampsia is a multisystemic and multifactorial disorder that complicates pregnancy and is characterized by new-onset hypertension after the 20th week of gestation accompanied by proteinuria or systemic findings such as renal…
- Conditions
- Preeclampsia (PE), Hypertension ,Pregnancy, Retinal Microvascular Changes, Hypertensive Disorders of Pregnancy
- Trial name
- PE-OCTA (NCT07874191)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Pregnancy Induced Hypertension, Pregnancy Related
SD-OCT Measurement of the Human Retina in Pregnancy With Pre-existing or De Novo Hypertension and Without Hypertension
The complications of long-standing severe and acute severe elevations in systemic blood pressure (hypertension) may involve large vessels as well as smaller vessels, these latter comprising what is known as the microcirculation.
- Trial name
- NCT04286217
- Volunteers
- 155 people
- Sponsor
- University of Calgary
Diabetic Retinopathy, GLP-1
Assessment of Retinal-Angio Findings In Patients With Diabetes Type II Treated With Novel Antidiabetic Therapies
ARIADNE is a prospective observational cohort study of patients with type 2 diabetes mellitus (T2DM) treated with daily metformin and scheduled to initiate treatment with newer antidiabetic agents, such as sodium-glucose…
- Conditions
- Diabetic Retinopathy, GLP-1, SGLT 2 Inhibitors, Endothelial Dysfunction
- Trial name
- ARIADNE (NCT07602348)
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Athens
Diabetes Type 1, Diabetic Retinopathy
Assessment of Retinal Microcirculation in Patients With Type 1 Diabetes Mellitus
Type 1 diabetes mellitus (T1DM) is associated with an increased lifetime risk of developing diabetic retinopathy, a leading cause of visual impairment among working-age adults worldwide.
- Conditions
- Diabetes Type 1, Diabetic Retinopathy, Microvascular Circulation, Retinal Microvascular Disease
- Trial name
- NCT07705321
- Testing
- Optical Coherence Tomography Angiography (OCTA)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Athens
Hypertension, Vascular Function
Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.
This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and/or individualized exercise training intervention on blood pressure and vascular health.
- Conditions
- Hypertension, Vascular Function, Fitness Testing, Metabolism Changes
- Trial name
- Antitension (NCT06823570)
- Testing
- Individualized exercise therapy, Lifestyle recommendations
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
OCTA, Severe Brain Injury
Effect of the Stellate Ganglion Block on the Retinal Microcirculation
Surges in the sympathetic nervous system occur at the ictus of a variety of neurological critical illnesses including intracranial hemorrhage and ischemic stroke.
- Conditions
- OCTA, Severe Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage
- Trial name
- NCT06797752
- Testing
- OCTA Scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center