Clinical trials: Retinal Vascular Disorder
Diabetic Retinopathy, Cataract
Cataract Surgery with Near Normal Eye Pressure in Patients with Diabetic Retinopathy
Diabetes mellitus is a chronic metabolic disease that can lead to visual impairment and eye complications such as diabetic retinopathy and diabetic macular edema.
- Trial name
- NNIOP-PHACO (NCT06617273)
- Testing
- Ophthalmosurgical handpiece with active anterior chamber pressure sensing and regulation
- Where
- Austria
- Volunteers
- 72 people
- Sponsor
- Medical University Innsbruck
Central Serous Chorioretinopathy, Age Related Macular Degeneration
PRedictive Factors and Changes From Treatment in iPCV Versus CSR Versus nAMD With afLibercept
The presence of PEDs in nAMD, CSR and iPCV can present a diagnostic challenge in the elderly population; despite detailed diagnostic testing to differentiate these three conditions, misdiagnosis and mistreatment still occurs.
- Conditions
- Central Serous Chorioretinopathy, Age Related Macular Degeneration, Idiopathic Poplypoidal Choroidal Vasculopathy
- Trial name
- PRaCTICAL (NCT02681783)
- Testing
- aflibercept
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetes Mellitus, Diabetic Retinopathy
Serum GPER-1 and Oxidant/Antioxidant Levels on Retinopathy in Diabetic Patients
Observational, comparative, cross-sectional study
- Conditions
- Diabetes Mellitus, Diabetic Retinopathy, Hormones
- Trial name
- NCT04930224
- Testing
- The effect of GPER-1 on the formation of diabetic retinopathy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Intracerebral Hemorrhage
Insights From the Retina on Cerebral Microvascular Dysfunction in Haemorrhagic Stroke
Fundoscopy, optical coherence tomography (OCT) and OCT-angiography (OCTA) are established examinations and bear minimal risks. The recognition of retinal microvascular signs will enhance the pathophysiological understanding of…
- Trial name
- RETINA-ICH (NCT04363619)
- Testing
- OCT and OCTA
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- University of Zurich
Diabetic Retinopathy, Age-Related Macular Degeneration
Function and Structure Imaging in Different Retinal Diseases: Retinal Leakage Analyzer Versus Optical Coherence Tomography
The main objective of this observational study is to characterize and correlate functional and structural changes at the retinal level using the Retinal Leakage Analyzer (RLA) and the Optical Coherence Tomograph (OCT).
- Conditions
- Diabetic Retinopathy, Age-Related Macular Degeneration, Macular Edema
- Trial name
- NCT00797524
- Where
- Portugal
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Retinopathy, Diabetic, Diastolic Dysfunction
REWARD: Using the REtina as a Window To Detect Cardiac microvasculAR Dysfunction In Diabetes Mellitus
Retinopathy may be associated with diastolic dysfunction and/or coronary flow reserve in the heart, and albuminuria in diabetic patients.
- Conditions
- Retinopathy, Diabetic, Diastolic Dysfunction, Microalbuminuria
- Trial name
- NCT04025996
- Testing
- Cardiac Assessments and Eye Assessments
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Diabetes Mellitus, Glaucoma
Smartphone Screening for Eye Diseases
To validate new screening instruments for eye disease, increase eye care access in underserved communities, and provide a scientifically implemented method to set up programs for eye disease screening.
- Conditions
- Diabetes Mellitus, Glaucoma, Age Related Macular Degeneration, ROP
- Trial name
- NCT03076697
- Testing
- Fundus photography
- Volunteers
- 472 people
- Sponsor
- University of Michigan
Diabetic Retinopathy
Integrating DR Into Mainstream Health System in Bangladesh
Diabetes mellitus is a leading cause of death and disability. Diabetic Retinopathy (DR) is an eye disease that affects the eyesight of about 21.3% persons with diabetes in Bangladesh in a way that is irreversible because of the…
- Trial name
- NCT03658980
- Testing
- Health Education Intervention
- Where
- Bangladesh
- Volunteers
- 299 people
- Sponsor
- Hiroshima University
Diabetic Retinopathy, Neurotrophic Keratitis
An Investigator-Initiated Study to Assess the Association of Diabetic Retinopathy Severity Scale (DRSS) With Level of Decreased Corneal Sensitivity
Evaluate the association between level of decreased corneal sensitivity and diabetic retinopathy severity scale
- Trial name
- Assess (NCT05566717)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical Center Ophthalmology Associates
Diabetic Retinopathy, Macular Edema
Visual Function, Center Point Thickness and Macular Volume After Photocoagulation
The purpose of this study is to correlate changes of visual function three weeks after photocoagulation for macular edema, with changes of center point thickness and macular volume.
- Trial name
- NCT00906659
- Where
- Mexico
- Volunteers
- 89 people
- Sponsor
- Hospital Juarez de Mexico
Diabetes, Diabetic Retinopathy
Pivotal Trial of Automated Artificial Intelligence (AI) Based System for Early Diagnosis of Diabetic Retinopathy
In this pivotal trial, we aim to perform a prospective study to find the efficacy of iPredict-DR, an artificial intelligence (AI) based software tool on early diagnosis of Diabetic Retinopathy (DR) in the primary care and…
- Trial name
- NCT07151001
- Testing
- No intervention
- Where
- United States
- Volunteers
- 922 people, healthy volunteers welcome
- Sponsor
- iHealthScreen Inc
Neovascular Age-Related Macular Degeneration
Study of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular Degeneration
Neovascular age-related macular degeneration is characterized by the presence of choroidal neovascularization (CNV), which consists of abnormal blood vessels originating from the choroid that can lead to hemorrhage, fluid…
- Trial name
- SWIFT (NCT04264819)
- Testing
- RTH258/Brolucizumab
- Where
- 51 sites in France
- Volunteers
- 295 people
- Sponsor
- Novartis Pharmaceuticals
Central Retinal Vein Occlusion
Spontaneous Retinal Artery Pulses (SPARs) as a Prognostic Determinant of Central Retinal Vein Occlusions (CRVO) in Patients With or Without Intravitreal Aflibercept Injections
Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy. It induces circulatory slowdown and blood stasis, which can appear as retinal hemorrhages.
- Trial name
- PULSOV (NCT04793100)
- Testing
- Ophthalmologic exam at inclusion and 12 months after CRVO, Treatment standardization with aflibercept
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Retinal Vein Occlusion, Macular Edema
Efficacy of an Intravitreal DEX Implant in Retinal Vein Occlusion Following Treatment With Anti-VEGF Injections.
To test the efficacy of a 0.7 mg intravitreal dexamethasone implant (Ozurdex®) on macular function and recalcitrant macular edema associated with retinal vein occlusion following treatment with 2 or more prior intravitreal…
- Trial name
- NCT01449682
- Testing
- Ozurdex
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Retina Macula Institute
Age-Related Macular Degeneration
Five-year Incidence of Age-related Macular Degeneration in the Central Region of Portugal
To assess the five-year incidence of AMD in a population from the central region of Portugal, previously phenotypically characterized.
- Trial name
- AMDIncidencePT (NCT02748824)
- Where
- Portugal
- Volunteers
- 5,996 people, healthy volunteers welcome
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Eye Diseases, Diabetic Retinopathy
Deep Learning for Fluorescein Angiography and Optical Coherence Tomography Macular Thickness Map Image Translation
Diabetic macular edema (DME) is one of the leading causes of visual impairment in patients with diabetes. Fluorescein angiography (FA) plays an important role in diabetic retinopathy (DR) staging and evaluation of retinal…
- Trial name
- NCT05105620
- Testing
- Fluorescein Angiography, Optical coherence tomography
- Where
- Egypt
- Volunteers
- 708 people
- Sponsor
- Assiut University
Diabetic Retinopathy
Perfluorocarbon Perfused Vitrectomy and 3D Vitrectomy System in Advanced Diabetic Retinopathy
To investigate the feasibility and advantages of using perfluorocarbon liquid (PCL) perfusion to remove vitreous during suction-cutting vitrectomy using a dual, dynamic drive (3D)technology.
- Trial name
- NCT00407108
- Testing
- Vitrectomy
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Retinal Telangiectasis, Coats Disease
Interest of Intravitreal Injections of Anti-VEGF as Initial and Adjuvant Treatment in Coats Disease
Coats disease is a predominantly unilateral progressive retinal vascular disease, characterized by retinal telangiectasias with intra- or subretinal exudate deposits, which can lead to retinal detachment and one-sided blindness.
- Trial name
- COATS-VEGF (NCT03940690)
- Testing
- Anti-VEGF injections of bevacizumab, Laser
- Where
- 6 sites in France
- Volunteers
- 18 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Diabetic Retinopathy
Macular Edema Incidence/Severity Reduction With Nevanac
The purpose of this study is to evaluate NEVANAC in patients with diabetic retinopathy who developed macular edema (ME) within 90 days following cataract surgery.
- Trial name
- NCT00939276
- Testing
- Nepafenac ophthalmic suspension, 0.1% (NEVANAC®), Nepafenac ophthalmic suspension vehicle
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Alcon Research
Central Retinal Vein Occlusion With Macular Edema
Comparison of Intravitreal Anti-VEGF Versus Combination Therapy in Central Retinal Vein Occlusion
To compare the effect of intravitreal-Bevacizumab and Triamcinolone with intravitreal-Bevacizumab alone on visual acuity and central foveal thickness in patients with macular edema secondary to central retinal vein occlusion.
- Trial name
- CRVO (NCT04812977)
- Testing
- Group A
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Hayatabad Medical Complex
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.