Clinical trials: Retrograde Intrarenal Surgery, open to volunteers
Kidney Stone, Retrograde Intrarenal Surgery (RIRS)
Multimodal Opioid-Free Anesthesia in RIRS
The goal of this clinical trial is to evaluate whether a dexmedetomidine-ketamine based opioid-free anesthesia (OFA) protocol can provide effective analgesia compared to conventional fentanyl-based anesthesia in adult patients…
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery (RIRS), Postoperative Pain
- Trial name
- NCT07636070
- Testing
- Dexmedetomidine-Ketamine Opioid-Free Anesthesia, Fentanyl-Based Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- murat sahin
Renal Calculi
Role of Pre-stenting Before Retrograde Intrarenal Surgery With Miniaturized Flexible Ureteroscopes
This prospective randomized controlled trial will compare retrograde intrarenal surgery performed after routine preoperative ureteral stenting with direct retrograde intrarenal surgery without planned preoperative stenting in…
- Trial name
- NCT07773090
- Testing
- Preoperative double-J ureteral stenting followed by retrograde intrarenal surgery, Direct retrograde intrarenal surgery without planned preoperative ureteral stenting
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Al-Azhar University
Renal Calculi
Comparison of Lithotomy Versus Lateral Position in Retrograde Intrarenal Surgery for Lower Calyceal Stones Less Than 2 cm
Retrograde intrarenal surgery (RIRS) is an established minimally invasive treatment for renal stones, particularly for lower calyceal stones less than 2 cm, offering acceptable stone-free rates with low morbidity.
- Trial name
- NCT07310966
- Testing
- Lithotomy Position, Lateral position
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Menoufia University
Urolithiasis
Clinical Evaluation of the Pelvic Floor Fatigue Index (PFFI)
Background: Ureteral stent-related symptoms vary considerably among patients despite similar surgical procedures and stent characteristics.
- Trial name
- PFFI (NCT07763613)
- Testing
- Ureteroscopy / Retrograde Intrarenal Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Kidney Stones, Nephrolithiasis
Effect of Complete Suction-Induced Collapse of the Renal Collecting System at the End of RIRS on Early Postoperative Outcomes
The purpose of this study is to evaluate whether actively suctioning the renal collecting system to induce a "collapse" state at the end of retrograde intrarenal surgery (RIRS) can reduce postoperative pain and infection in…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07535281
- Testing
- Complete suction-induced collapse, Standard RIRS with natural drainage
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangdong Sacred Heart Hospital
Kidney Stones, Nephrolithiasis
DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones
Kidney stones are a common health problem and may recur frequently, which can affect quality of life and kidney function. Retrograde intrarenal surgery (RIRS) is a minimally invasive treatment used for renal stones, but treatment…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07516535
- Testing
- Direct In-Scope Suction, Flexible and Navigable Suction Ureteric Access Sheath
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Kidney Stone
Evaluation of Renal Injury After RIRS Using Shear-Wave Elastography
This study aims to evaluate changes in renal parenchyma following retrograde intrarenal surgery (RIRS) using shear-wave elastography.
- Trial name
- NCT07615452
- Testing
- Aspiration-assisted ureteral access sheath, Standard ureteral access sheath
- Volunteers
- 60 people
- Sponsor
- Cengiz Canakci, MD
Renal Stone
Supervised Endoscopic Tele-controlled Intelligent Lithotripsy
This is a phase I feasibility study to investigate the use of a novel intelligent robotic retrograde intrarenal surgery (RIRS) platform.
- Trial name
- SENTINEL-1 (NCT07411391)
- Testing
- RIRS using the TaloStone T1000 RIRS platform
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Chinese University of Hong Kong
Renal Stone, Stone in Calyceal Diverticulum
Retrograde Intrarenal Surgery Versus Extracorporeal Shockwave Lithotripsy
The study's aim is to determine which treatment modality, either ESWL or RIRS, is more effective in achieving stone clearance for lower calyceal calculi.
- Trial name
- NCT07510178
- Testing
- Retrograde intrarenal surgery, Extracorporeal shock wave lithotripsy
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Urolithiasis, Nephrolithiasis
Access Sheaths With Aspiration for Renal RetrOgrade Surgery, Randomized CompArative Outcomes
The goal of this clinical trial is to learn whether the ClearPetra ureteral access sheath (Coloplast) is more effective than the Navigator ureteral access sheath (Boston Scientific) in treating intrarenal kidney stones of 1-3 cm…
- Conditions
- Urolithiasis, Nephrolithiasis, Kidney Calculi, Ureteroscopy
- Trial name
- ARROCA01 (NCT07678255)
- Testing
- ClearPetra ureteral access sheath, Navigator ureteral access sheath
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Urolithiasis
COMPARISON OF FANS VS CONVENTIONAL URETERAL ACCESS SHEATH in RIRS on POSTOPERATIVE ACUTE KIDNEY INJURY
Kidney stone disease is a common condition, and retrograde intrarenal surgery (RIRS) is a minimally invasive procedure frequently used to remove kidney stones.
- Trial name
- FANS (NCT07685587)
- Testing
- flexible and navigable ureteral access sheath, conventional ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Namik Kemal University
Kidney Calculi, Urolithiasis
Antibiotic Irrigation and Suction Ureteral Access Sheath in RIRS
Retrograde intrarenal surgery (RIRS) is a widely used treatment for kidney stones; however, postoperative infectious complications remain a significant concern.
- Conditions
- Kidney Calculi, Urolithiasis, Urinary Tract Infections
- Trial name
- NCT07655050
- Testing
- Standard Retrograde Intrarenal Surgery, Gentamicin Irrigation, Suction-Enabled Ureteral Access Sheath
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Hitit University
Nephrolithiasis, Renal Calculi
Comparison of Extracorporeal Shock Wave Lithotripsy Versus Retrograde Intrarenal Surgery in the Management of Renal Calculi
This study is being carried out in patients with kidney stones measuring between 1 and 2 centimeters. Kidney stones are common in Pakistan and can cause severe pain, infection, and repeated hospital visits.
- Trial name
- NCT07261995
- Testing
- Extracorporeal Shock Wave Lithotripsy (ESWL), Retrograde Intrarenal Surgery (RIRS)
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Ziauddin Hospital
Kidney Stones, Nephrolithiasis
Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery
This randomized clinical trial will compare four ventilation strategies during retrograde intrarenal surgery performed under general anesthesia.
- Trial name
- RIRS-VENT (NCT07705646)
- Testing
- Standard Ventilation, Hypoventilation, Intermittent Apnea Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Pediatric Renal Stone
Retrograde Intrarenal Surgery Versus Mini Percutaneous Nephrolithotomy
Pediatric nephrolithiasis accounts for approximately 2-3% of all stone disease cases, with recent reports indicating a rising prevalence of up to 10.6%. This increasing incidence poses a growing public health concern.
- Trial name
- NCT07700251
- Testing
- Retrograde Intrarenal Surgery
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Valley University
Urolithiasis, Kidney Calculi
Human Voice vs AI-Cloned Voice Audio Added to Written Consent Before Ureteroscopy or Retrograde Intrarenal Surgery (AUDIO-CONSENT)
Before kidney stone surgery with a flexible or semirigid ureteroscope, patients must read and sign a written consent form, but many patients find these forms long and hard to understand.
- Conditions
- Urolithiasis, Kidney Calculi, Ureteral Calculi, Informed Consent
- Trial name
- AUDIO-CONSENT (NCT07859436)
- Testing
- Standard written informed consent, Human-voice audio consent recording, AI-cloned-voice audio consent recording
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Aydin Adnan Menderes University
Urolithiasis
Analysis of the Effectiveness and Safety of RIRS Under Local Anesthesia and Its Influencing Factors
Retrograde intrarenal surgery (RIRS) is a well-established technique and is the first-line treatment option for upper urinary tract stones <2cm.
- Trial name
- NCT06737497
- Testing
- retrograde Intrarenal Surgery ( RIRS ) under local anesthesia
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Calculi
Using Retrograde Intrarenal Surgery for Managing Staghorn Renal Stones.
This prospective, randomized study is comparing the safety and efficacy of using two types of ureteral access sheaths in managing staghorn renal stones by retrograde intrarenal surgery.
- Trial name
- NCT07342361
- Testing
- Retrograde intrarenal surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Urolithiasis
Risk Factors for Postoperative Fever and Sepsis Following Retrograde Intrarenal Surgery
This prospective clinical study aims to evaluate preoperative, intraoperative, and postoperative characteristics of patients undergoing retrograde intrarenal surgery (RIRS) for urinary stone disease.
- Trial name
- SARIS (NCT07295925)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- TC Erciyes University
Stone, Kidney, Stones, Kidney
Impact of Surgical Position on Stone-Free Rates in Retrograde Intrarenal Surgery
The goal of this clinical trial is to determine whether the surgical position during retrograde intrarenal surgery (RIRS) affects stone-free rates in adults with kidney stones.
- Conditions
- Stone, Kidney, Stones, Kidney, Stone;Renal
- Trial name
- POS-RIRS-RCT (NCT06809582)
- Testing
- The T-Tilt position
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ondokuz Mayıs University