Clinical trials: Retrograde Intrarenal Surgery (RIRS)
Kidney Stones
Evaluation of Different Treatment Modalities for Lower Pole and Renal Pelvis Stones
It is aimed to evaluate the treatment results, rates of success and complications, and injury given to the kidney by measuring preoperative and postoperative blood urea, creatinine, Cystatin C and Netrin-1 levels and urine…
- Trial name
- NCT02522676
- Testing
- Endoscopic kidney stone surgery, Non-invasive kidney stone treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Selcuk University
Nephrolithiasis
Is There Any Relation Between Pain and Stone Location in Retrograde Intrarenal Surgery?
We want to serach the relationship between the pain degree and stone localisation in kidney in Retrograde intrarenal surgery
- Trial name
- NCT02430883
- Testing
- Retrograde Intrarenal Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Diskapi Teaching and Research Hospital
Kidney Stone
Intrarenal Pressure Monitoring Via Flexible and Navigable Suction Ureteral Access Sheath in Retrograde Intrarenal Surgery
This study evaluates the use of a novel intrarenal pressure (IRP)-monitoring flexible and navigable suction ureteral access sheath (FANS) in retrograde intrarenal surgery (RIRS) for renal stones.
- Trial name
- NCT06729801
- Testing
- IRP-Monitoring Flexible and Navigable Suction Ureteral Access Sheath (FANS), Conventional FANS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Stones, Retrograde Intrarenal Surgery
Tamsulosin and Intraureteral Aminophylline for Ureteral Access During RIRS
This multicenter randomized controlled trial will evaluate whether preoperative tamsulosin, intraureteral aminophylline, or their combination can improve ureteral access during primary retrograde intrarenal surgery for renal…
- Conditions
- Renal Stones, Retrograde Intrarenal Surgery, Ureteral Access Sheath Placement
- Trial name
- TAM-AMIN-UAS (NCT07623876)
- Testing
- Tamsulosin, Intraureteral Aminophylline
- Where
- 3 sites in Egypt
- Volunteers
- 322 people
- Sponsor
- Beni-Suef University
Kidney Stones, Nephrolithiasis
Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery
This randomized clinical trial will compare four ventilation strategies during retrograde intrarenal surgery performed under general anesthesia.
- Trial name
- RIRS-VENT (NCT07705646)
- Testing
- Standard Ventilation, Hypoventilation, Intermittent Apnea Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Kidney Stone
A Novel Method for Retrograde Intrarenal Surgery (RIRS)
In this prospective randomised controlled study, investigators aims to evaluate the effect of 80 mg gentamicin added to 3 liters of irrigation fluid on stone free rate, intraoperative and postoperative complications during RIRS…
- Trial name
- NCT05202158
- Testing
- Addition of gentamicin to irrigation fluid during RIRS, Only irrigation fluid during RIRS
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Training and Research Hospital
Renal Stone
Supervised Endoscopic Tele-controlled Intelligent Lithotripsy
This is a phase I feasibility study to investigate the use of a novel intelligent robotic retrograde intrarenal surgery (RIRS) platform.
- Trial name
- SENTINEL-1 (NCT07411391)
- Testing
- RIRS using the TaloStone T1000 RIRS platform
- Where
- 2 sites in Hong Kong
- Volunteers
- 15 people
- Sponsor
- Chinese University of Hong Kong
Kidney Stone
Tip Bendable Suction Ureteral Access Sheath vs. Traditional Ureteral Access Sheath in Retrograde Intrarenal Stone Surgery
Nephrolithiasis is the most common chronic kidney condition and affecting approximately one in every 10-17 people in the world[1,2].
- Trial name
- NCT05952635
- Testing
- Tip bendable suction ureteral access sheath
- Where
- China
- Volunteers
- 320 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Health Related Quality of Life
Determinants of Health-related Quality of Life for Patients After Renal Lithotripsy: PNL Versus RIRS
Percutaneous nephrolithotomy (PNL) and Retrograde intrarenal surgery (RIRS) are well-established procedures for renal stone fragmentation; however, the morbidity, hospitalization, and lost work hours associated with these…
- Trial name
- NCT05851339
- Testing
- SF- 36 Questionnaire
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- South Valley University
Kidney Stone, Retrograde Intrarenal Surgery (RIRS)
Multimodal Opioid-Free Anesthesia in RIRS
The goal of this clinical trial is to evaluate whether a dexmedetomidine-ketamine based opioid-free anesthesia (OFA) protocol can provide effective analgesia compared to conventional fentanyl-based anesthesia in adult patients…
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery (RIRS), Postoperative Pain
- Trial name
- NCT07636070
- Testing
- Dexmedetomidine-Ketamine Opioid-Free Anesthesia, Fentanyl-Based Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- murat sahin
Renal Stones
RIRS Versus ESWL for the Treatment of Renal Stones
To evaluate the effectiveness of RIRS (retrograde intrarenal surgery) and ESWL (extracorporeal shockwaves lithotripsy) in the treatment of renal stone ranging form 6 to 20 mm size.
- Trial name
- NCT02645058
- Testing
- RIRS, ESWL, Rigid and flexible ureteroscope
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Kidney Stones, Nephrolithiasis
DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones
Kidney stones are a common health problem and may recur frequently, which can affect quality of life and kidney function. Retrograde intrarenal surgery (RIRS) is a minimally invasive treatment used for renal stones, but treatment…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07516535
- Testing
- Direct In-Scope Suction, Flexible and Navigable Suction Ureteric Access Sheath
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Renal Stone
The Effect of Anesthesia Type on RIRS
Retrograde intrarenal surgery (RIRS) with flexible ureteroscopy is based on video monitoring of urinary tract during operation. Therefore, shaking vision on monitor can bother surgeons and make them tired.
- Trial name
- NCT03373617
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Kidney Stone
Evaluation of Renal Injury After RIRS Using Shear-Wave Elastography
This study aims to evaluate changes in renal parenchyma following retrograde intrarenal surgery (RIRS) using shear-wave elastography.
- Trial name
- NCT07615452
- Testing
- Aspiration-assisted ureteral access sheath, Standard ureteral access sheath
- Volunteers
- 60 people
- Sponsor
- Cengiz Canakci, MD
Kidney Stone, Ureteroscopy
Retrograde Intrarenal Stone Surgery - A Method of Treating the ESWL Resistant Kidney Stone
Is it possible to decrease the intrarenal pressure in the kidney during endoscopic management of kidney stone by topical administration of drugs? In order to secure fewer complications in ureteroscopic operations the…
- Trial name
- NCT00323843
- Testing
- Isoproterenol
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Fredericia Hosptial
Retrograde Intrarenal Surgery (RIRS), Urolithiasis
Evaluation of Sevoflurane Consumption During Initial Phase of Minimal-Flow Anesthesia in Retrograde Intrarenal Surgery
This study aimed to compare the effects of minimal-flow (0.5 L/min) and low-flow (1.0 L/min) sevoflurane anesthesia on agent consumption, anesthetic depth, and cardiorespiratory safety during retrograde intrarenal surgery (RIRS).
- Conditions
- Retrograde Intrarenal Surgery (RIRS), Urolithiasis, Minimal-flow Anesthesia, Sevoflurane
- Trial name
- SEVOMIN-RIRS (NCT07248917)
- Testing
- Sevoflurane Anesthesia with Minimal-flow, Sevoflurane Anesthesia with Low-flow
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Urolithiasis
COMPARISON OF FANS VS CONVENTIONAL URETERAL ACCESS SHEATH in RIRS on POSTOPERATIVE ACUTE KIDNEY INJURY
Kidney stone disease is a common condition, and retrograde intrarenal surgery (RIRS) is a minimally invasive procedure frequently used to remove kidney stones.
- Trial name
- FANS (NCT07685587)
- Testing
- flexible and navigable ureteral access sheath, conventional ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Namik Kemal University
Urolithiasis
Effect of Use of Ureteral Access Sheath on Levels of Netrin-1 in Patients Undergoing RIRS
In this study, it is aimed to evaluate whether use of a ureteral access sheath (UAS) during retrograde intrarenal surgery (RIRS) due to kidney stone has any effect on protecting the kidney functions by measuring blood and urine…
- Trial name
- NCT02533414
- Testing
- RIRS with UAS, RIRS without UAS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Retrograde Intrarenal Surgery
General Versus Spinal Anesthesia in RIRS
The impact of anesthesia type on Retrograde Intrarenal Surgery (RIRS) outcomes remains a subject of ongoing debate. Several studies have compared general anesthesia (GA) and spinal anesthesia (SA) in endourological procedures…
- Trial name
- NCT07664384
- Where
- Egypt
- Volunteers
- 252 people
- Sponsor
- South Valley University
Renal Stone Disease
Direct In-Scope Suction Versus Standard Flexible Ureterorenoscopy
This prospective study aims to compare the clinical, perioperative, and postoperative outcomes of flexible ureterorenoscopy using a direct in-scope suction system (DISS) with standard flexible ureterorenoscopy in patients…
- Trial name
- NCT07864194
- Testing
- Standard flexible ureterorenoscope, Flexible ureterorenoscope with direct in-scope suction
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hitit University