Clinical trials: Retroperitoneal Neoplasms
Sarcoma
Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Retroperitoneal Sarcoma
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed.
- Trial name
- STRASS (NCT01344018)
- Testing
- therapeutic conventional surgery, 3-dimensional conformal radiation therapy
- Where
- 37 sites in United States, Belgium and 11 more
- Volunteers
- 266 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Adrenal Tumors
Anesthesia Management of Retroperitoneal Adrenalectomies
This study is a prospective, perioperative evaluation of hemodynamic and respiratory parameters in patients undergoing retroperitoneoscopic adrenalectomies.
- Trial name
- NCT00894335
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Kliniken Essen-Mitte
Adult Soft Tissue Sarcoma
Proton Beam Radiation Therapy in Treating Patients With Retroperitoneal Sarcoma
RATIONALE: Specialized radiation therapy, such as proton beam radiation therapy, that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue in patients with…
- Trial name
- NCT01034566
- Testing
- Proton Beam Radiation Therapy
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Testicular Cancer
A Clinical Trial of Primary Retroperitoneal Lymph Node Dissection in Patients With Testicular Seminoma With Limited Retroperitoneal Metastases
Testicular cancer represents 1% of adult neoplasms and is the most common solid malignancy in young men. At diagnosis, approximately 90% of cases are germ cell tumours (GCT), categorised as either seminoma (55-60%) or…
- Trial name
- RPLND-Seminoma (NCT06932458)
- Testing
- Retroperitoneal Lymph Node Dissection
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University, Canada
Morbidity, Gynaecologic Cancer
Blood Lactate Level With Paraaortic Lymph Node Dissection
This study was designed as a prospective observational study.
- Trial name
- NCT06648330
- Testing
- Paraaortic retroperitoneal lymph node dissection
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Duygu Akyol
Lymphocele, Gynecologic Cancer
Impact of Peritoneal Closure and Retroperitoneal Drainage on Patients Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection
To elucidate whether peritoneal closure and retroperitoneal drainage can benefit clinical outcome of early gynecologic cancer patients who underwent retroperitoneal lymph node dissection.
- Trial name
- NCT03765320
- Testing
- Peritoneal closure, Retroperitoneal drainage
- Where
- Taiwan
- Volunteers
- 204 people
- Sponsor
- Far Eastern Memorial Hospital
Retroperitoneal Sarcoma, Margin, Tumor-Free
Retroperıtoneal Soft-Tıssue Sarcomas
: Soft Tissue Sarcomas are rare mesenchymal tumors with many subtypes. Clean margin-wide resection is recommended for treatment. The guidelines recommend that sarcoma treatments be carried out in sarcoma centers.
- Trial name
- NCT05044624
- Testing
- retroperitoneal mass excision
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Laparoscopic Ultrasound
Laparoscopic Ultrasound Guided Minimal Invasive Excision of Intra-/Retroperitoneal Tumors
Patients included in the study went through standard preoperative preparation and were informed about potential conversion to open surgery.
- Trial name
- NCT04911634
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Pheochromocytoma Malignant
Abdominal Circumference as a Predictor of Operative Time in Retroperitoneal Adrenalectomy for Pheochromocytoma
This retrospective observational study examines whether abdominal circumference is associated with operative time in patients undergoing retroperitoneal adrenalectomy for pheochromocytoma.
- Trial name
- NCT07339241
- Testing
- Retroperitoneal Adrenalectomy
- Volunteers
- 159 people
- Sponsor
- Asan Medical Center
Stage III Adult Soft Tissue Sarcoma, Recurrent Adult Soft Tissue Sarcoma
Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Primary or Recurrent Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Conditions
- Stage III Adult Soft Tissue Sarcoma, Recurrent Adult Soft Tissue Sarcoma, Stage IVA Adult Soft Tissue Sarcoma, Stage IIB Adult Soft Tissue Sarcoma
- Trial name
- NCT00017160
- Testing
- doxorubicin, filgrastim, ifosfamide
- Where
- 235 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association
Testicular Cancer, Testicular Germ Cell Tumor
Minimally-invasive ICG-guided Retroperitoneal Sentinel Lymph Node Dissection in the Primary Staging of Testicular Cancer Versus Standard of Care
Testicular cancer is highly curable, but approximately 20-30% of patients with clinical stage I disease harbor occult retroperitoneal lymph node metastases that are not detected by conventional imaging.
- Trial name
- RAISN 2 (NCT07699640)
- Testing
- ICG-Guided Retroperitoneal Sentinel Lymph Node Biopsy, Radical Inguinal Orchiectomy
- Where
- 10 sites in Finland, Germany
- Volunteers
- 171 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Retroperitoneal Neoplasms
Contrast-enhanced vs. B-mode Ultrasound-guided Percutaneous Biopsy of Retroperitoneal Tumors
Background: Retroperitoneal tumors are typically large and inhomogeneous, with a variable amount of necrosis within the tumor mass which decreases the diagnostic yield of biopsy (false negative or inadequate).
- Trial name
- NCT05659433
- Testing
- CEUS-guided percutaneous biopsy, B-mode US-guided percutaneous biopsy
- Where
- Romania
- Volunteers
- 160 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Pelvic Tumor, Retroperitoneal Tumor
Contribution of 3D Modeling in Surgical Management of Pediatric Retroperitoneal and Pelvic Tumors
This study's purpose is the comparison of the automatically segmented 3D model to the reference manual segmentation, based on the Dice precision index.
- Trial name
- 3D-PEDSURG (NCT06418243)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Retroperitoneal Sarcoma
Preoperative Proton Radiotherapy for Retroperitoneal Sarcoma
The goal of this study is to evaluate radiation treatment intended to increase the chance of curing your sarcoma and decrease the side effects of proton therapy.
- Trial name
- SA03 (NCT00901836)
- Testing
- Preoperative proton therapy, Surgery
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Sarcoma, Sarcoma, Leiomyo-, Adult
Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients
This is a cohort study aimed at developing a stratified medicine approach for personalised neoadjuvant chemotherapy (NCT) in high-risk soft tissue sarcoma (STS) patients with dedifferentiated liposarcoma (DDLPS), leiomyosarcoma…
- Conditions
- Sarcoma, Sarcoma, Leiomyo-, Adult, Sarcoma, Synovial, Adult, Soft Tissue Sarcoma (STS)
- Trial name
- PANTHR-S (NCT07432932)
- Testing
- Observational Translational Study
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Adrenal Tumor, Adrenal Mass
Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical Conditions
With our retrospective study the investigators show the limitations of the posterior retroperitoneal adrenalectomy by analyzing anatomical parameters.
- Conditions
- Adrenal Tumor, Adrenal Mass, Pheochromocytoma, Conn Adenoma
- Trial name
- NCT04071561
- Testing
- Posterior retroperitoneal adrenalectomy (PRA), Lateral transperitoneal adrenalectomy (LTA)
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- University of Basel
Renal Tumor
Comparing Two Different Approaches in Robotic-Assisted Renal Surgery
The purpose of this study is to determine if the novel TR approach is superior to the standard RP approach. The anticipated study outcome is a time saving of at least 30% from first skin incision to detection of the renal artery…
- Trial name
- PIONEER-OPT (NCT05377632)
- Testing
- Robotic-assisted laparoscopic partial nephrectomy (LPN) or laparoscopic nephrectomy (LN)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Lukas J Hefermehl
Sarcoma,Soft Tissue
Neoadjuvant Irradiation of Retroperitoneal Soft Tissue Sarcoma With Ions Retro-Ion
The study is a randomized, open, prospective phase II study. The aim of the study is to evaluate the safety and feasibility of a hypofractionated, accelerated radiation approach based on the incidence of grade 3-5 NCI Common…
- Trial name
- Retro-Ion (NCT04219202)
- Testing
- Proton radiation, Carbon Ion radiation
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- University Hospital Heidelberg
Chylous Ascites, Abdominal Neoplasm
Oral Iohexol in the Management of Chylous Ascites After After Retroperitoneal or Extended Lymphadenectomy
The goal of this clinical trial is to assess the effectiveness of oral iohexol in the treatment of postoperative chylous ascites. It will also learn about the safety of oral iohexol.
- Conditions
- Chylous Ascites, Abdominal Neoplasm, Pelvic Neoplasms, Retroperitoneal Lymph Node Metastasis
- Trial name
- NCT06820320
- Testing
- oral iohexol, Lymphangiography and Embolization
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences