Clinical trials: Revision Arthroplasty
Hip Osteoarthritis, Hip Disease
MDR - G7 Neutral and G7 Freedom Constrained Neutral Acetabular Liners
The objective of this consecutive series PMCF study is to collect data confirming safety, performance and clinical benefits of the G7 Freedom Constrained Liners when used for primary and revision total hip arthroplasty (implants…
- Conditions
- Hip Osteoarthritis, Hip Disease, Hip Fractures, Hip Injuries
- Trial name
- NCT04093739
- Testing
- G7 Freedom Constrained Liners
- Sponsor
- Zimmer Biomet
Arthroplasty, Replacement, Knee
Early Clinical Results of Mobile-Bearing Revision Total Knee Arthroplasty
Long term follow-up is needed to determine whether current Mobile Bearing revision Total Knee Arthroplasty (TKA) designs will improve implant longevity.
- Trial name
- MBT (NCT01398800)
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Colorado Joint Replacement
Arthroplasty, Hip Revision
Trident II Revision Outcomes Study
The purpose of this study is to review the performance and success rate of an FDA cleared cementless hip replacement part called the Trident II Tritanium Acetabular Shell.
- Trial name
- NCT04317586
- Testing
- Trident II Tritanium Acetabular Shell for Revision
- Where
- 10 sites in United States
- Volunteers
- 17 people
- Sponsor
- Stryker Orthopaedics
Prosthesis-Related Infections
Prospectively Observational Evaluation of Clinical Outcomes in Two-stage Revision for Periprosthetic Knee Infection
Total knee arthroplasty (TKA) infection is a complication requiring multiple hospitalizations, operations, and outpatient visits placing a significant burden on both patient and treating surgeons.
- Trial name
- NCT04622280
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Taiwan University Hospital
Hip Osteoarthritis, Arthroplasty Complications
DELTA Multihole TT Study
A retrospective study evaluating clinical and radiographic early outcomes of total hip arthroplasty and revision hip arthroplasty with DELTA Multihole TT cup.
- Conditions
- Hip Osteoarthritis, Arthroplasty Complications, Hip Dysplasia
- Trial name
- NCT04375345
- Testing
- hip arthroplasty
- Where
- Slovakia
- Volunteers
- 40 people
- Sponsor
- University Hospital Bratislava
PJI, Bone and Joint Infection
Periarticular Penetration of Cefazolin and Clindamycin in Second Stage Revision Arthroplasty of the Hip
To prevent periprosthetic joint infection (PJI), optimal penetration of antibiotics into the joint-space is needed. In revision arthroplasty, the incidence of PJI is increased compared to primary arthroplasty.
- Conditions
- PJI, Bone and Joint Infection, Pharmacokinetics
- Trial name
- CONCENTRATE (NCT05421312)
- Testing
- sampling blood, Sampling synovial fluid, Sampling bone tissue
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Loosening, Prosthesis, Hip Arthropathy
Radiographic Stability of Hip Prosthesis Prior to Revision Surgery
The goal of this validation study is to compare the preoperative implant stability, assessed by Implant Movement Analysis (IMA), provocation dual CT scans, with the intraoperative stability evaluation in revision hip arthoplasty.
- Trial name
- MULTICIMA (NCT06924567)
- Testing
- Implant motion provocation CT
- Where
- 6 sites in Denmark, Norway and 1 more
- Volunteers
- 600 people
- Sponsor
- Georgios Tsikandylakis, MD PhD
Osteoarthritis, Avascular Necrosis
Arcos Revision Stem: Evaluation of Clinical Performance
The primary purpose of this study is to evaluate the clinical performance of the Arcos Revision Stem system, determine the stability of the implants, and evaluate any relationship between Paprosky bone defect level and the…
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Deformity
- Trial name
- NCT01820611
- Testing
- Arcos Revision Stem System
- Where
- 5 sites in Finland, Spain and 2 more
- Volunteers
- 74 people
- Sponsor
- Zimmer Biomet
Patellofemoral Osteoarthritis, Arthroplasty Complications
Failure Analysis of Patellofemoral Arthroplasty
The purpose of the retrospective cohort study is 1) to determine preoperative risk factors for revision af patellofemoral arthroplasty, and 2) to provide a detailed description of indications for revision after patellofemoral…
- Conditions
- Patellofemoral Osteoarthritis, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT04772625
- Testing
- Patellofemoral arthroplasty
- Where
- Denmark
- Volunteers
- 550 people
- Sponsor
- Anders Odgaard
Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis
MDR - Longevity IT Oblique and Offset Liners
The objective of this retrospective enrollment/prospective follow-up consecutive series PMCF study is to collect data confirming safety, performance, and clinical benefits of the Longevity IT Oblique and Offset liners when used…
- Conditions
- Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis, Protrusio Acetabuli, Traumatic Arthritis
- Trial name
- NCT05980234
- Testing
- Total Hip Arthroplasty with Longevity IT Oblique Liners, Total Hip Arthroplasty with Longevity IT Offset Liners
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Zimmer Biomet
Arthroplasty, Replacement, Hip
MARS MRI in Revision THA With a Ceramic Femoral Head and Titanium Sleeve
Revision total hip replacement using a ceramic head utilizes a titanium sleeve which introduced another articulation into the system that may lead to a local soft tissue reaction.
- Trial name
- NCT05686915
- Testing
- MARS MRI, Titanium Labs, Cobalt Labs
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Colorado Joint Replacement
Revision Total Knee Replacement
Early Outcome Assessment of Revision Total Knee Arthroplasty Using Metaphyseal Sleeves
Metaphyseal sleeves, through their design, could allow reconstruction of the knee in cases of severe bone loss by allowing rigid internal fixation and proper alignment of the extremity and components.
- Trial name
- NCT01156558
- Sponsor
- Rothman Institute Orthopaedics
Surgical Incision
A Prospective, Randomized, Comparative Study to Assess the Prevention of Surgical Site Infection (SSI's) in Revision Total Joint Arthroplasty Patients Treated With Single-Use Negative Pressure Wound Therapy (PICO) or Standard Care Dressings (AQUACEL Ag SURGICAL Dressing).
The primary aim of this study is to determine if the SSI rate following revision total hip and knee arthroplasty is reduced in patients treated with the PICO device compared to patients with traditional postoperative dressings.
- Trial name
- NCT03180346
- Testing
- PICO, Aquacel
- Where
- United States
- Volunteers
- 494 people
- Sponsor
- Rothman Institute Orthopaedics
Knee Replacement, Knee Replacement Revision
Prevalence and Incidence of Multiple Revisions Following Knee Arthroplasty in Denmark 1998-2021: A Nationwide Population-based Study
The purpose of this study is to investigate the incidence and prevalence rates of multiply revised knee arthroplasty patients in Denmark from 1998-2021.
- Trial name
- EMKAR ONE (NCT06064318)
- Testing
- Revision
- Where
- Denmark
- Volunteers
- 161,384 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis Shoulder, Rheumatoid Arthritis
TESS V3 Modular Total Shoulder System PMCF
This is a multicenter, retrospective and prospective, non-controlled post market surveillance study. The objectives of this study are to confirm safety, performance and clinical benefits of the T.E.S.S.® Version 3 Anatomic and…
- Conditions
- Osteoarthritis Shoulder, Rheumatoid Arthritis, Rheumatoid Arthritis Shoulder, Avascular Necrosis
- Trial name
- NCT05002959
- Testing
- Anatomic TESS V3, Reverse TESS V3
- Where
- 2 sites in France
- Volunteers
- 67 people
- Sponsor
- Zimmer Biomet
Congenital Hip Dysplasia, Hip Osteoarthritis
Pelvic Osteotomy Of The Total Hip Replacement
This observational study aims to learn about the outcomes in the previously operated patient and whether pelvic bone rearrangement surgery was a success.
- Trial name
- NCT06209255
- Testing
- Pelvic Osteotomy - Ganz Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Van Bölge Eğitim ve Araştırma Hastanesi
Revision of Total Hip Arthroplasty
Effectiveness of Intraoperative Cell Salvage in Aseptic Revision Total Hip Arthroplasty.
Intraoperative cell salvage is an important measure of patient blood management but its effectiveness in patients undergoing revision total hip arthroplasty remains unclear.
- Trial name
- NCT05237830
- Testing
- Use of Cell Salvage in revision of total hip arthroplasty
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- University of Liege
Osteoarthritis, Degenerative Arthritis
PINNACLE® DM RSA Study
The primary objective is to establish the mean superior cup migration of the PINNACLE® Dual Mobility Construct using model-based RSA over the first two years post-implantation.
- Conditions
- Osteoarthritis, Degenerative Arthritis, Revision Arthroplasty
- Trial name
- PIN DM (NCT05357664)
- Testing
- Total Hip Arthroplasty, Revision Total Hip Arthroplasty
- Where
- 3 sites in Canada
- Volunteers
- 11 people
- Sponsor
- DePuy Orthopaedics
Arthroplasty, Replacement, Knee
Multigen Plus H Study and AMF TT Cones
The aim of this study is to assess the clinical, patient-reported, and radiographic outcomes of a revision Total Knee Arthroplasty with Multigen Plus H and AMF TT Cones.
- Trial name
- NCT04884542
- Testing
- Revision Total Knee Arthroplasty
- Where
- 2 sites in Belgium, Slovakia
- Volunteers
- 43 people
- Sponsor
- Limacorporate S.p.a
Arthropathy Shoulder
TXA in Revision Total Shoulder Arthroplasty
This is a phase IV, randomized, single-blind, single-center study comparing calculated total blood loss, surgical drain output and hematoma formation in patients who receive 2 doses of Tranexamic Acid (TXA) versus control group…
- Trial name
- NCT04650698
- Testing
- Tranexamic acid (TXA) injection
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health