Clinical trials: Rheumatic Fever
Rheumatic Fever
Clinical Audit on the Managment in Assiut University Children Hospital
clinical audit on the Managment of rheumatic fever in assiut university children hospital.
- Trial name
- NCT03281863
- Testing
- C reactive protein, anti streptolysin o antibody test ,erythrocyte sedimentation rate
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Rheumatic Fever
Clinical Trial to Assess Safety and Immunogenicity of a Synthetic Vaccine Against Streptococcus Pyogenes
This is a double-blind, randomized, placebo-controlled phase I clinical trial with dose-escalation of a synthetic vaccine against Streptococcus pyogenes.
- Trial name
- NCT03998592
- Testing
- Streptococcus pyogenes vaccine (50 µg), Streptococcus pyogenes vaccine (100 µg), Streptococcus pyogenes vaccine (200 µg)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Butantan Institute
Inflammatory Rheumatism
HIIT for Inflammatory Rheumatic Disease: Man vs Machine
The purpose of this study is to compare two modes of delivering high-intensity interval training (HIIT) in a population with inflammatory rheumatic disease over 10 weeks.
- Trial name
- NCT04649528
- Testing
- Effective endurance 4x4 training - Supervised, Effective endurance 4x4 training - APP
- Where
- Norway
- Volunteers
- 49 people
- Sponsor
- Molde University College
Rheumatic Heart Disease, Rheumatic Fever
The Genetic Basis of Acquired Heart Disease in Africa
Background: An acquired heart disease is one that a person gets after they are born. Two of these are rheumatic heart disease (RHD) and endomyocardial fibrosis (EMF).
- Conditions
- Rheumatic Heart Disease, Rheumatic Fever, Endomyocardial Fibrosis, Acquired Heart Disease
- Trial name
- NCT02124109
- Where
- 2 sites in Nigeria, Uganda
- Volunteers
- 736 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Systemic Lupus, Rheumatoid Arthritis
Yellow Fever Vaccine in Patients With Rheumatic Diseases
According to World Health Organization (WHO), since December 2016, Brazil is showing a significant increase in cases of yellow fever in humans.
- Conditions
- Systemic Lupus, Rheumatoid Arthritis, Spondyloarthritis, Inflammatory Myopathy
- Trial name
- NCT03430388
- Testing
- Yellow Fever vaccine (17D)
- Where
- Brazil
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Fatigue, Inflammatory Rheumatism
Guided Self-Management Intervention Targeting Fatigue in Rheumatic Inflammatory Diseases
Fatigue is common and debilitating in rheumatic inflammatory diseases as for other chronical medical conditions. The purpose of this study is to develope and evaluate a cognitive behavioural intervention targeting fatigue.
- Trial name
- NCT03216616
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 40 people
- Sponsor
- Diakonhjemmet Hospital
Secondary Cardiac Damage in Rheumatic Fever
Prevalence of Secondary Cardiac Damage in Rheumatic Fever Patients and Penicillin Secondary Prophylaxis
According to American Heart Association criteria, patients who have had Rheumatic Fever (RF) should be treated with antibiotic prophylaxis.
- Trial name
- NCT03183180
- Testing
- Echocardiogram
- Volunteers
- 100 people
- Sponsor
- Assuta Hospital Systems
Rheumatic Heart Disease, Acute Rheumatic Fever
Rheumatic Heart Disease in Peru: Prevalence and Cardiovascular Outcomes Among Schoolchildren
Rheumatic heart disease remains a major challenge in low and middle income countries. Early detection of clinically silent valvular lesions by screening echocardiography allows timely implementation of secondary antibiotic…
- Trial name
- NCT02353663
- Testing
- Echocardiography
- Where
- 2 sites in Peru, Switzerland
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Inflammatory Rheumatism, Psoriatic Arthritis
Does Etanercept Influence Tweak Modulation of Inflammation During Inflammatory Rheumatisms (Psoriatic Arthritis and Rheumatoid Arthritis)?
TWEAK (TNF weakly inducer of apoptosis) is a type II-transmembrane protein, member of the TNF ligand superfamily that can be cleaved to function as a soluble cytokine.
- Conditions
- Inflammatory Rheumatism, Psoriatic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT02164214
- Testing
- etanercept Treatment
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Rheumatic Fever
Efficacy of BLIS K12 as Preventive Measure for Rheumatic Children
The purpose of this study is to determine whether daily treatment with Streptococcus Salivarius BLIS K-12 prevents streptococcal throat infection in children that have had an episode of rheumatic fever.
- Trial name
- NCT02407106
- Testing
- Streptococcus Salivarius BLIS K12
- Volunteers
- 30 people
- Sponsor
- Kaplan Medical Center
Inflammatory Rheumatism
Impact of a Telenursing Service on Satisfaction and Health Outcomes of Children With Inflammatory Rheumatic Diseases
Paediatric rheumatisms represent a large group of inflammatory and non-inflammatory diseases of the locomotion system. The annual rate incidence of children diagnosed with rheumatic disease in Switzerland (canton of Vaud) is 56.8…
- Trial name
- NCT01511341
- Testing
- Telenursing
- Where
- Switzerland
- Volunteers
- 55 people
- Sponsor
- University of Applied Sciences of Western Switzerland
Rheumatic Heart Disease, Mitral Stenosis
Genetic Susceptibility to Rheumatic Heart Disease in the Pacific Region
The purpose of this study is to investigate whether there are genetic differences between patients with rheumatic heart disease and members of the general population.
- Trial name
- NCT02188862
- Where
- 3 sites in Fiji, New Caledonia and 1 more
- Volunteers
- 2,372 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Rheumatic Arthritis
Phase I Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of YHB1411-2 in Healthy Male Volunteers
A block-randomized, double-blind, placebo-controlled, single-dose escalating, phase I clinical trial to evaluate the safety, tolerability and pharmacokinetics of YHB1411-2 in healthy male volunteers
- Trial name
- NCT01525147
- Testing
- YHB1411-2: Level 2, YHB1411-2: Level 3, YHB1411-2: Level 4
- Where
- South Korea
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Rheumatic Arthritis
Efficacy of Physiotherapy on the Health and Quality of Life of the Rheumatic Patient
Despite leading cause of morbidity, treatment strategies for Rheumatic diseases are geared almost exclusively toward medical-pharmacological area away from offering the patient the possibility of an interdisciplinary approach to…
- Trial name
- NCT02020668
- Testing
- Physiotherapy, Wait list control
- Where
- India
- Volunteers
- 82 people
- Sponsor
- Macmillan Research Group UK
Acute Rheumatic Fever
Plasma Adiponectin Levels and Relations With Cytokines in Children With Acute Rheumatic Fever
We aimed to investigate if adiponectin facilitates diagnosis of ARF by analyzing adiponectin levels in acute and convalescent periods of the acute rheumatic fever and by comparing results with that of healthy control group; also…
- Trial name
- NCT01886846
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University