Clinical trials: Rheumatoid Arthritis, completed
Rheumatoid Arthritis
A Rheumatoid Arthritis (RA) Study Treating Signs and Symptoms of RA in People With RA & Receiving Methotrexate
This clinical study is investigating AMG 719, an investigational drug, for the treatment of patients who have Rheumatoid Arthritis and who are taking Methotrexate.
- Trial name
- NCT00038298
- Testing
- AMG 719, AGM 719
- Volunteers
- 53 people
- Sponsor
- Amgen
Rheumatoid Arthritis (RA), Spondyloarthritis (SA)
Inflammatory Arthritis and Tango
The hypothesis is that pleasure brought by argentine tango practice would increase total physical activity of patients with chronic inflammatory arthritis.
- Trial name
- IATANGO (NCT03840785)
- Testing
- Argentine tango
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Clermont-Ferrand
Rheumatoid Arthritis
Masitinib in Combination With Methotrexate, in Treatment of Patients With Active Rheumatoid Arthritis
A 12-week with possible extension, phase II study to compare efficacy and safety of masitinib at 3 and 6 mg/kg/day in combination with methotrexate, in treatment of patients with active rheumatoid arthritis refractory to standard…
- Trial name
- NCT00913432
- Testing
- masitinib
- Volunteers
- 20 people
- Sponsor
- AB Science
Rheumatoid Arthritis
Safety of TofAcitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA)- Cardiovascular Endpoints
There are two main aims of this study. First aim is to compare the risk of cardiovascular events (including myocardial infarction or stroke), between patients treated with tofacitinib and patients treated with TNF inhibitors…
- Trial name
- NCT04772248
- Testing
- Tofacitinib, TNF Inhibitor
- Where
- United States
- Volunteers
- 105,711 people
- Sponsor
- Brigham and Women's Hospital
Rheumatoid Arthritis
The Usability and Injection Time of the Physiolis Syringe and Autoinjector in Rheumatoid Arthritis Patients
This was an open-label, Phase 2 study designed to obtain user experience data (Phase A) and injection time data (Phase B) in experienced adalimumab patients injected with the Physiolis pre-filled syringe and autoinjector used to…
- Trial name
- NCT01163617
- Testing
- Adalimumab delivered in current syringe, Adalimumab delivered in Physiolis syringe, Adalimumab delivered in current autoinjector
- Where
- 10 sites in United States
- Volunteers
- 85 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Tele-nursing
The Effect of Nursing Follow-Up by Phone on The Self-Efficacy,Pain,Disease Activity in Rheumatoid Arthritis Patients
The aim of this study was to determine the effect of nursing follow-up by phone on the self-efficacy status, pain, and disease activity of individuals with RA using biological agents.
- Trial name
- NCT05863338
- Testing
- NURSING FOLLOW-UP BY PHONE
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Cumhuriyet University
Rheumatoid Arthritis
A Study to Determine the Safety and Efficacy of LX3305 in Subjects With Active Rheumatoid Arthritis
The primary objective of this study is to determine the safety of LX3305 in a dose escalation compared with placebo over 12 weeks in subjects with active rheumatoid arthritis (RA).
- Trial name
- NCT01417052
- Testing
- 50 mg LX3305 QD, 100 mg LX3305 QD, 150 mg LX3305 QD
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lexicon Pharmaceuticals
Rheumatoid Arthritis, Axial Spondyloarthritis
Patient Reported Outcomes Reported Via PC / Tablet Home Versus Touch Screen at Hospital Among Patients With Arthritis
To investigate if electronic reporting of patient reported outcome measures from home is comparable to the traditional touch-screen solution to hospital among patients with rheumatoid arthritis and axial spondyloarthritis
- Trial name
- PRO (NCT02818478)
- Testing
- Reporting of patient reported outcome measures
- Volunteers
- 42 people
- Sponsor
- Henrik Gudbergsen
Arthritis, Rheumatoid
Study to Evaluate Safety and Effects of Tofacitinib and Biologic Disease Modifying Antirheumatic Drugs in People Treated for Rheumatoid Arthritis
This is a secondary structured database observational study conducted in Rheumatoid Arthritis (RA) patients treated with biologic and nonbiologic DMARDs, including tofacitinib, collected as part of the CorEvitas Japan RA…
- Trial name
- NCT05572567
- Where
- Japan
- Volunteers
- 1,972 people
- Sponsor
- Pfizer
Rheumatoid Arthritis
Safety Study of a Single Dose of REGN88(SAR153191)in Patients With Rheumatoid Arthritis
This study will test the safety and tolerability (how the body reacts to the drug) of REGN88 and placebo (an inactive substance that contains no medicine) in patients with Rheumatoid Arthritis.
- Trial name
- NCT01055899
- Testing
- REGN88
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Regeneron Pharmaceuticals
Arthritis, Rheumatoid
A Study of CNTO 136 (Sirukumab) Administered Subcutaneously in Japanese Patients With Active Rheumatoid Arthritis Unresponsive to Methotrexate or Sulfasalazine
The purpose of this study is to evaluate the safety and efficacy of sirukumab as a single therapy in Japanese patients with moderately to severely active rheumatoid arthritis (RA) who have not responded to treatment with…
- Trial name
- NCT01689532
- Testing
- Sirukumab 100 mg, Sirukumab 50 mg
- Where
- 17 sites in Japan
- Volunteers
- 122 people
- Sponsor
- Janssen Pharmaceutical K.K.
Rheumatoid Arthritis
A Phase 3 Study of NI-071 in Participants With Rheumatoid Arthritis (RADIANCE)
The purpose of this study was to demonstrate similarity of NI-071 (proposed biosimilar to infliximab) to US REMICADE® (reference product) in terms of safety and efficacy in participants with rheumatoid arthritis (RA) not…
- Trial name
- NCT02990806
- Testing
- NI-071, Remicade
- Where
- 134 sites in United States, Czechia and 6 more
- Volunteers
- 683 people
- Sponsor
- Nichi-Iko Pharmaceutical Co., Ltd.
Arthritis, Rheumatoid
Treatments Against RA and Effect on FDG-PET/CT
In a randomized controlled clinical trial, investigators will compare the effects on [18F]-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) from two treatment regimens in rheumatoid arthritis (RA)…
- Trial name
- TARGET (NCT02374021)
- Testing
- Methotrexate, Sulfasalazine, Hydroxychloroquine
- Where
- 31 sites in United States
- Volunteers
- 159 people
- Sponsor
- Brigham and Women's Hospital
Rheumatoid Arthritis
Comparative Clinical Trial of Efficacy and Safety of BCD-055 and Remicade® in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis
BCD-055-3 is international multi-center comparative double-blind randomized clinical trial of efficacy and safety of BCD-055 (JSC "BIOCAD", Russia) and Remicade® in combination with methotrexate in patients with active rheumatoid…
- Trial name
- NCT02762838
- Testing
- BCD-055, Remicade®, Methotrexate
- Where
- 39 sites in Belarus, India and 1 more
- Volunteers
- 426 people
- Sponsor
- Biocad
Rheumatoid Arthritis
Evaluation of Rheumatoid Arthritis Disease Education Literature
Rheumatoid arthritis is an inflammatory disease that results in joint inflammation, pain and swelling. It may progress to advance stages that render patients unable to carry out their daily activities.
- Trial name
- ERADEL (NCT03336684)
- Testing
- Patient education
- Where
- 2 sites in Pakistan
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Sjogren's Syndrome
Effects of Acupuncture on Sjögren's Syndrome
Sjögren's syndrome (SS) is a multisystemic chronic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands, resulting in salivary and lacrimal glands hypofunction, with symptoms of dry eyes and mouth.
- Trial name
- NCT04056221
- Testing
- Acupuncture
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Ana Carolina Fragoso Motta, DDS, PhD
Arthritis, Juvenile Rheumatoid
Safety and Efficacy of Measles, Mumps, Rubella Vaccination in Juvenile Idiopathic Arthritis
Background: The safety of vaccination in patients with autoimmune diseases using immune suppressive therapy is often discussed. Previous studies in Juvenile Idiopathic Arthritis (JIA) patients showed no increase in disease…
- Trial name
- VAART (NCT00731965)
- Testing
- Measles, Mumps, Rubella vaccination
- Where
- 5 sites in Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- N.M. Wulffraat
Arthritis, Juvenile Rheumatoid
Identification of Genes Involved in Juvenile Idiopathic Arthritis by Wholel Exome Sequencing
Juvenile idiopathic arthritis (JIA) is considered to be a multifactorial disease caused by a combination of environmental factors and predisposing genetic factors.
- Trial name
- GenesinJIA (NCT02067962)
- Testing
- Blood sample
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Seropositive RA
The BCD-089 (aIL6R) in Patients With Active Rheumatoid Arthritis
The study is Phase II randomized, double-blind, placebo-controlled clinical trial to evaluate efficacy and safety, pharmacokinetics and pharmacodynamics of 2 dosing regimens (qw and q2w, s/c) of monoclonal antibody to IL6R…
- Trial name
- AURORA (NCT03455842)
- Testing
- BCD-089, 162 mg, s/c, qw, BCD-089, 162 mg, s/c, q2w
- Where
- 4 sites in Belarus, Russia
- Volunteers
- 105 people
- Sponsor
- Biocad
Rheumatoid Arthritis
Role of Vitamin D3 Supplementation With Conventional Synthetic Disease Modifying Antirheumatic Drugs(csDMARD) in Rheumatoid Arthritis Patients
Several studies suggested low serum level of vitamin D have been associated with rheumatoid arthritis. So, the present study was designed to investigate the effect of vitamin D supplementation along with CsDMARD in patients with…
- Trial name
- NCT05078502
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 58 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
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