Clinical trials: Rheumatoid Arthritis (RA), open to volunteers
Rheumatoid Arthritis (RA)
Nutrition in Rheumatoid Arthritis
Background: Individuals with Rheumatoid Arthritis (RA) often experience persistent symptoms such as pain and stiffness despite modern pharmacological treatments. They also have an increased risk of cardiovascular disease.
- Trial name
- NUTRA (NCT06831331)
- Testing
- Healthy diet based on NNR2023, Control/waiting-list
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Vastra Gotaland Region
Rheumatoid Arthritis (RA)
Acceptability of a Nurse-led Telehealth Remote Self-monitoring Model of Care in Patients With Rheumatoid Arthritis
Canada urgently needs new ways to provide rheumatology care that improve treatment and make it easier for people to get high-quality care.
- Trial name
- NCT07525856
- Testing
- Nurse-led telehealth remote self-monitoring
- Where
- 4 sites in Canada
- Volunteers
- 104 people
- Sponsor
- CHU de Quebec-Universite Laval
Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA)
A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases
This is an open-label, multi-ascending dose (MAD) phase 1 study, with dose expansion at selected doses, in adult patients with select autoimmune rheumatic diseases including systemic lupus erythematosus (SLE) or rheumatoid…
- Trial name
- NCT06647069
- Testing
- SAR448501
- Where
- 8 sites in Australia, Bosnia and Herzegovina and 3 more
- Volunteers
- 62 people
- Sponsor
- Sanofi
Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc)
A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases
This study evaluates the safety and efficacy of YTS109 cells in adults with relapsed/refractory autoimmune diseases, such as Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc), etc.
- Conditions
- Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc), Inflammatory Myopathy, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
- Trial name
- NCT06978647
- Testing
- YTS109 cell
- Where
- China
- Volunteers
- 12 people
- Sponsor
- China Immunotech (Beijing) Biotechnology Co., Ltd.
Rheumatoid Arthritis (RA
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Rheumatoid Arthritis
A Phase I, open-label study of CLN-978 in patients with treatment-refractory rheumatoid arthritis.
- Trial name
- NCT06994143
- Testing
- CLN-978
- Where
- 4 sites in Germany, Italy
- Volunteers
- 37 people
- Sponsor
- Cullinan Therapeutics Inc.
Diffuse Cutaneous Systemic Sclerosis, Rheumatoid Arthritis (RA)
Controlling Hyperactive Immunity With Long-lived Lymphocytes
This study is a Phase 1/2, open-label clinical trial to test an experimental treatment called QEL-005 in adults with two autoimmune conditions: diffuse cutaneous systemic sclerosis (dcSSc) and difficult-to-treat rheumatoid…
- Conditions
- Diffuse Cutaneous Systemic Sclerosis, Rheumatoid Arthritis (RA), Systemic Sclerosis (SSc), Autoimmune Rheumatologic Disease
- Trial name
- CHILL (NCT07473154)
- Testing
- QEL-005
- Where
- 10 sites in Germany, Spain and 1 more
- Volunteers
- 16 people
- Sponsor
- Quell Therapeutics Limited
Rheumatoid Arthritis (RA)
Musclockeletal Ultra-sound Assessment of Pulley Inflammation in Rheumatoid Arthrits Pateints
assessment of pulley inflammation in rheumatoid arthrits patients using muscloskeletal ultra-sound
- Trial name
- NCT07878611
- Volunteers
- 80 people
- Sponsor
- Sohag University
Rheumatoid Arthritis (RA)
HRV Variation in Rheumatoid Arthritis
The goal of this observational study is to determine the association between continuous Heart Rate Variability (HRV) measured by the Oura ring and Rheumatoid Arthritis (RA) disease activity.
- Trial name
- NCT07878975
- Testing
- Oura Ring
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Central Florida
Arthritis, Psoriatic (PsA), Arthritis, Rheumatoid (RA)
Patient-Reported Outcomes Dashboard With Goal Setting to Support Shared Decision-Making in Inflammatory Arthritis
The goal of this clinical trial is to learn whether showing patient-reported symptoms and personal treatment goals to rheumatology clinicians on a dashboard in the electronic health record improves shared decision-making for…
- Trial name
- NCT07865390
- Testing
- Patient-Reported Outcomes Dashboard With Goal Setting
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Northwestern University
Rheumatoid Arthritis (RA), Transcutaneous Vagus Nerve Stimulation
the Effect and Mechanism of Percutaneous Auricular Electrical Stimulation in Preventing Central Sensitization Pain in Patients With Rheumatoid Arthritis
This multicenter, randomized, double-blind, sham-controlled trial aimed to evaluate the preventive efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) against central-sensitization-related pain in high-risk…
- Trial name
- taVNS for Pain (NCT07870564)
- Testing
- taVNS
- Volunteers
- 124 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Rheumatoid Arthritis (RA)
A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis
The aim of this study is to evaluate the safety of F8IL10 when administered by intra-articular injection and to determine the maximum tolerated dose (MTD) in order to establish the recommended dose (RD) in patients with Reumatoid…
- Trial name
- DekaJoint (NCT07245992)
- Testing
- F8IL10
- Where
- 2 sites in Italy
- Volunteers
- 54 people
- Sponsor
- Philogen S.p.A.
Rheumatic Diseases, Rheumatoid Arthritis (RA)
Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis
In the context of this randomized controlled study, patients who are diagnosed with Rheumatoid arthritis in Cerrahpaşa Faculty of Medicine Hospital, will be taken into a rehabilitation program by a qualified physiotherapist to…
- Trial name
- NCT07274124
- Testing
- Pain Neuroscience Education, Vagal Nerve Stimulation, Structured Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Medipol University
Rheumatoid Arthritis (RA)
Evaluation of Dapagliflozin and Empagliflozin as Adjunctive Therapy to Methotrexate in Patients With Rheumatoid Arthritis
This study aims to evaluate the efficacy and safety of dapagliflozin and empagliflozin as adjunctive therapies to methotrexate in patients with rheumatoid arthritis who have active disease despite stable methotrexate treatment.
- Trial name
- NCT07864688
- Testing
- Dapagliflozin, Empagliflozin, Methotrexate
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Al-Azhar University
Rheumatoid Arthritis (RA), Manegmentof Rheumatoid Arthritis
the Effect of Ginkgo Biloba on Rheumatoid Arthritis Patients
this study aims to measure The Effect of Gingko Biloba on the Clinical Outcome of Rheumatoid Arthritis Patients ,the outcomes are hsCRp,calprotectin,DAS-28,HAQ-DI
- Trial name
- NCT07709312
- Testing
- Ginkgo Biloba Extract (120 mg ) manufuctured by EMA PHARM
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Rheumatoid Arthritis (RA
Dysphagia in Rheumatoid Arthritis
The primary goal of this cross-sectional study is to assess risk factors/predictors for dysphagia in RA. The secondary goals include demonstrating whether flexible fiberoptic pharyngolaryngoscopy can detect…
- Trial name
- NCT07401732
- Testing
- flexible fiberoptic pharyngolaryngoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Rheumatoid Arthritis (RA), Crohn's Disease (CD)
Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis
This study is a randomized controlled clinical trial evaluating whether two therapeutic dietary approaches - a ketogenic diet and a carnivore (lion) diet - can improve quality of life, reduce symptoms, and influence measures of…
- Conditions
- Rheumatoid Arthritis (RA), Crohn's Disease (CD), Ulcerative Colitis (UC)
- Trial name
- NCT07524244
- Testing
- Ketogenic diet, Carnivore (Lion) Diet
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Fuller Research Foundation
Rheumatic Disorder, Rheumatoid Arthritis (RA)
DETECTRA: Remote Monitoring to Detect Rheumatoid Arthritis Flares and Treatment Response
The goal of this clinical trial is to learn if the DETECTRA remote monitoring platform can help clinicians detect rheumatoid arthritis (RA) disease flares earlier and more reliably, as well as identify response and non-response…
- Trial name
- Pix-Monitor (NCT07857993)
- Testing
- DETECTRA, Standard of Care (SOC)
- Where
- 3 sites in Austria, Germany
- Volunteers
- 320 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Rheumatoid Arthritis (RA)
National Cohort of Subjects at Risk of Developing Rheumatoid Arthritis
PROMESS 1 is a multicenter cohort interventional study aiming at analyzing the factors associated with the risk of developing clinical arthritis among exposures or combinations of exposures in patients at risk of rheumatoid…
- Trial name
- PROMESS_1 (NCT06876064)
- Testing
- Blood test, Urine test, stool collection
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis (RA)
Safety and Efficacy of TollB-001 Tablets in Moderate to Severe Rheumatoid Arthritis
The goal of this study is to evaluate the safety, pharmacokinetic (PK) characteristics, and preliminary efficacy of a new oral chemical drug in : adults aged 18-70 years (male or female) with moderate to severe active rheumatoid…
- Trial name
- NCT07408024
- Testing
- TollB-001
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Toll Biotech Co. Ltd. (Beijing)
Rheumatoid Arthritis (RA), SSc-Systemic Sclerosis
Improving ILD Screening in Patients With RA and SSc Using EHR-Embedded CDS and PRO Tools
This is a quality improvement initiative that aims to find better ways to identify interstitial lung disease (ILD) early in people with rheumatoid arthritis (RA) or systemic sclerosis (SSc).
- Trial name
- ILD-QUI (NCT07849673)
- Testing
- EHR-Embedded CDS and PRO Tools Intervention
- Volunteers
- 800 people
- Sponsor
- Foundation for Advancing Science Technology Education and Research