Clinical trials: Rhinitis, Seasonal, Allergic
Seasonal Allergic Rhinitis
A Safety and Efficacy Study of Ciclesonide Nasal Aerosol in Subjects 6-11 Years With Seasonal Allergic Rhinitis (SAR)
This is a 2-week, multicenter, randomized, double-blind, placebo-controlled, parallel group, efficacy and safety study of ciclesonide nasal aerosol administered once daily to male and premenarchal female subjects 6 to 11…
- Trial name
- NCT01458275
- Testing
- Ciclesonide nasal aerosol 37 mcg, ciclesonide nasal aerosol 74 mcg
- Where
- 66 sites in United States
- Volunteers
- 847 people
- Sponsor
- Sumitomo Pharma America, Inc.
Grass Pollen Allergy
Safety and Efficacy of Grass Pollen Allergoid in the Treatment of Allergic Rhinoconjunctivitis
The trial is performed to assess efficacy and safety of the Grass Pollen Allergoid in Allergic Rhinoconjunctivitis
- Trial name
- NCT00263601
- Testing
- Allergovit 6-grasses
- Where
- Germany
- Volunteers
- 154 people
- Sponsor
- Allergopharma GmbH & Co. KG
Allergic Rhinitis
Efficacy of Artemisia Pollen Specific Allergen Immunotherapy
Allergic rhinitis (AR) is a noninfectious inflammatory disease of the nasal mucosa mediated by immunoglobulin E (IgE) after exposure to allergens.
- Trial name
- NCT05318157
- Testing
- AIT drops, Clarityne, Rhinocort and Emedastine Difumarate Eye Drops
- Where
- 3 sites in China
- Volunteers
- 150 people
- Sponsor
- Beijing Tongren Hospital
Treatment of the Signs and Symptoms of Seasonal Allergic Rhinitis
A Comparison of Mometasone Nasal Spray, Nasonex Nasal Spray, Nasonex Nasal Spray Suspension, & Placebo for Treatment of Seasonal Allergies for Safety, Efficacy, & Superiority in 1520 Male & Female Volunteers
The study will compare the safety and efficacy of a generic mometasone nasal spray to the reference listed drugs in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT02109185
- Testing
- Mometasone Furoate Monohydrate Nasal Spray, 50 μg/act., Nasonex® Nasal Spray, 50 μg/actuation, Nasonex® Nasal Spray Suspnsn, 50 μg/actuation
- Volunteers
- 1,307 people
- Sponsor
- Mylan Pharmaceuticals Inc
Allergic Rhinitis Due to Pollen, Allergic Conjunctivitis
Tyrosine Allergoid Paediatric and Adult Study
The primary objective of this 5-year study is to demonstrate non-inferiority of children compared to adults by exploring long-term effectiveness after treatment with TA Bäume (trees) and TA Gräser (grass) following a perennial…
- Conditions
- Allergic Rhinitis Due to Pollen, Allergic Conjunctivitis, Allergic Asthma
- Trial name
- NCT05186025
- Testing
- MATA trees or MATA grass
- Where
- Germany
- Volunteers
- 320 people
- Sponsor
- Allergy Therapeutics
Seasonal Allergic Rhinitis
Efficacy, Safety and Underlying Mechanisms of Sphenopalatine Ganglion Acupuncture for Seasonal Allergic Rhinitis
In recent years, a number of randomized controlled trials have confirmed the efficacy and safety of acupuncture in the treatment of allergic rhinitis (AR).
- Trial name
- NCT04052945
- Testing
- SPA acupuncture
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Beijing Tongren Hospital
Rhinitis, Allergic, Seasonal
Factors Predicting Efficacy of Allergen Injection Immunotherapy for Grass Pollen Hayfever
The purpose of this study is to determine at which point in the dosing regime grass pollen immunotherapy causes a significant reduction in the late skin response to allergen challenge.
- Trial name
- NCT00135629
- Testing
- Active injections of alum-adsorbed grass pollen vaccine (Alutard SQ)., Venepuncture: 100ml blood sample taken on 12 separate visits
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Imperial College London
Allergy
Efficacy and Safety Trial of SLITone(TM) Birch in Subjects With Hayfever
The trial is performed to assess the efficacy and safety of SLIT One birch for treatment of birch pollen induced allergy
- Trial name
- NCT00310466
- Testing
- Sublingual immunotherapy
- Where
- Germany
- Volunteers
- 226 people
- Sponsor
- ALK-Abelló A/S
Birch Pollen Allergy
Follow-up of Study AN004T to Assess the Persistence of AllerT Efficacy During the 2nd to 4th Season After Treatment
Study aiming to evaluate the efficacy of a 2-month pre-seasonal treatment with an AllerT 50 µg or 100 µg maintenance dose administered in previous study AN004T in reducing symptoms of allergic rhinoconjunctivitis during the 2nd…
- Trial name
- NCT02143583
- Where
- 22 sites in Denmark, France and 5 more
- Volunteers
- 196 people
- Sponsor
- Anergis
Seasonal Allergic Rhinitis
MP-AzeFlu Allergen Chamber - Onset of Action Study
This study is to assess the onset of action of fixed drug combination of azelastine hydrochloride and fluticasone propionate nasal spray (MP-AzeFlu) in treating the nasal symptoms of seasonal allergic rhinitis (SAR) induced by an…
- Trial name
- NCT03004131
- Testing
- Azelastine hydrochloride + fluticasone propionate nasal spray, fluticasone propionate nasal spray + loratadine
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Rhinitis, Allergic, Seasonal
A Phase II Study Evaluating Intranasal GSK256066 and Fluticasone Propionate in Subjects With Seasonal Allergic Rhinitis (SAR)
This is an 8 day, randomised, double blind, 3-way crossover trial of repeat doses of intranasal GSK256066 and fluticasone propionate in the Vienna Challenge Chamber in subjects with seasonal allergic rhinitis (SAR).
- Trial name
- NCT00612820
- Testing
- GSK256066, fluticasone propionate
- Where
- Austria
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinoconjunctivitis
Safety Study of Grass Pollen-derived Peptides to Treat Seasonal Allergic Rhinoconjunctivitis
The purpose of this study is to determine whether the oral administration of grass pollen peptides is safe and effective in the treatment of allergic rhinitis.
- Trial name
- NCT00833066
- Testing
- gpASIT+TM
- Where
- 4 sites in Belgium
- Volunteers
- 54 people
- Sponsor
- BioTech Tools S.A.
Seasonal Allergic Rhinitis
Placebo-Controlled Study of Mometasone Furoate Nasal Spray (MFNS) 200 mcg Once Daily (QD) in the Treatment of Seasonal Allergic Rhinitis (Study P05067)(COMPLETED)
This study is designed to assess the effectiveness of mometasone furoate nasal spay (MFNS) once daily (QD) compared with placebo in subjects with seasonal allergic rhinitis (SAR) in reducing the total nasal symptom score and the…
- Trial name
- NCT00453063
- Testing
- mometasone furoate
- Volunteers
- 426 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
Efficacy and Safety of Levocetirizine and Fexofenadine in Reducing Symptoms of Seasonal Allergic Rhinitis
No information was yet available over the effect of levocetirizine in children under 12 years. The aim of this double-blind, placebo-controlled study was to assess the efficacy and safety of levocetirizine in children from 6 to…
- Trial name
- NCT00542607
- Testing
- levocetirizine dihydrochloride
- Volunteers
- 94 people
- Sponsor
- UCB Pharma
Birch Pollen Allergy, Grass Pollen Allergy
Diagnostic Accuracy of the MADx Multi Array Xplorer (MAX 45k) Automated Laboratory System and the MADx Allergy Explorer Version 2 (ALEX²) - IgE Multiplex Test for the Diagnosis of Pre-defined Groups of Specific High-priority Allergens
About 20% of the general population are affected by an allergy - with an upward trend. Quite often, allergic people do not consider their disease as serious and suffer from subsequent complications, like allergic asthma, later in…
- Conditions
- Birch Pollen Allergy, Grass Pollen Allergy, House Dust Mite Allergy, Cat Allergy
- Trial name
- MADMAX (NCT04435678)
- Testing
- ALEX² test using the MAX 45k automated laboratory system
- Where
- 2 sites in Austria
- Volunteers
- 839 people
- Sponsor
- MacroArray Diagnostics GmbH
Allergy Pollen, Healthy
Iron and Pollen Allergy in Women
Iron deficiency and anemia are clearly associated with the onset of allergy and allergic diseases, whereas an improved iron status seems to prevent the onset of allergy in humans. Iron-deficiency can be absolute or functional.
- Trial name
- NCT03816800
- Testing
- ImmunoBon
- Where
- Austria
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Patients
The Effects of Sphenopalatine Ganglion Acupuncture in Patients With Seasonal Allergic Rhinitis
Sphenopalatine ganglion (SPG)-acupuncture has been shown to exhibit distinct effects in treatment of nasal inflammatory disease.
- Trial name
- NCT03282630
- Testing
- Sphenopalatine ganglion acupuncture
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tongren Hospital
Type I Hypersensitivity
Follow-up Investigation of Efficacy of Ragweed MATAMPL,and Placebo in Patients With Ragweed-induced Seasonal Allergic Rhinitis
Ragweed MATAMPL has been developed to provide pre-seasonal specific immunotherapy for patients with hypersensitivity to ragweed pollen (hay fever).
- Trial name
- NCT00325338
- Testing
- Ragweed MATAMPL
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Allergy Therapeutics
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal
Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
The purposes of this pilot safety study are to identify a dose of inhaled Clinical Center Reference Endotoxin (CCRE) that is well tolerated by allergic subjects that induces measurable increases in neutrophil content of induced…
- Conditions
- Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal, Asthma
- Trial name
- NCT00839189
- Testing
- Clinical Center Reference Endotoxin (CCRE)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Allergic Rhinoconjunctivitis, Chronic Urticaria
Pharmacokinetic Study of Bilastine in Children From 2 to < 12 Years of Age With Either Allergic Rhinoconjunctivitis (AR) or Chronic Urticaria (CU)
The conduct of this clinical trial is aimed at determining the most suitable dose regimen for children in different age groups, and secondarily to assess the safety and tolerability of bilastine in this paediatric population…
- Trial name
- NCT01081574
- Testing
- Bilastine
- Where
- 7 sites in Australia, Germany and 1 more
- Volunteers
- 36 people
- Sponsor
- Faes Farma, S.A.