Clinical trials: Rhinitis, Seasonal, Allergic
Seasonal Allergic Rhinitis
Comparison of the Effects of Desloratadine and Placebo in the Relief of Nasal Symptom Scores in Subjects With Seasonal Allergic Rhinitis to Cypress Pollen (Study P02836)
The purpose of this study was to demonstrate the efficacy (% of change from baseline) of desloratadine to improve the nasal total symptom score of SAR to cypress pollen.
- Trial name
- NCT00867191
- Testing
- Desloratadine
- Volunteers
- 233 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Study of the Efficacy and Safety of MK-0476 in Japanese Pediatric Participants With Seasonal Allergic Rhinitis (MK-0476-519)
This study will evaluate the efficacy and safety of montelukast (MK-0476) in the treatment of Japanese pediatric participants with seasonal allergic rhinitis (SAR).
- Trial name
- NCT01857063
- Testing
- Montelukast
- Volunteers
- 220 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial
Study for the Treatment of Intermittent Allergic Rhinitis With Desloratadine (Study P04683)
This study will investigate the effectiveness of desloratadine in treating subjects with allergic rhinitis (AR) who meet the criteria for intermittent allergic rhinitis.
- Trial name
- NCT00406783
- Testing
- 5-mg Desloratadine
- Volunteers
- 547 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204)
This is an efficacy and safety study of desloratadine (MK-4117) in Japanese participants with seasonal allergic rhinitis (SAR). The primary hypothesis of this study is that the change from Baseline in Total Nasal Symptom Score…
- Trial name
- NCT02320396
- Testing
- Desloratadine 5 mg
- Volunteers
- 449 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
Factors Predicting Efficacy of Allergen Injection Immunotherapy for Grass Pollen Hayfever
The purpose of this study is to determine at which point in the dosing regime grass pollen immunotherapy causes a significant reduction in the late skin response to allergen challenge.
- Trial name
- NCT00135629
- Testing
- Active injections of alum-adsorbed grass pollen vaccine (Alutard SQ)., Venepuncture: 100ml blood sample taken on 12 separate visits
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Imperial College London
Seasonal Allergic Rhinitis
Study of Mometasone Furoate Nasal Spray and Oxymetazoline Nasal Spray Given Together Once A Day To Treat Seasonal Allergic Rhinitis (P04500)
The primary objective of this study is to evaluate the efficacy of the combination of mometasone furoate nasal spray (MFNS) and oxymetazoline nasal spray (OXY) given together once a day in treating subjects with seasonal allergic…
- Trial name
- NCT00552110
- Testing
- OXY combination: mometasone furoate nasal spray (MFNS) and oxymetazoline nasal spray (OXY), mometasone furoate nasal spray (MFNS) once daily, oxymetazoline nasal spray (OXY) twice daily
- Volunteers
- 707 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Azelastine Allergen Chamber - Onset of Action Study
This study is to assess the Onset of Action and Efficacy of azelastine hydrochloride 0.15% in treating the nasal symptoms of seasonal allergic rhinitis (SAR) induced by an allergen challenge in an Environmental Exposure Unit…
- Trial name
- NCT06126952
- Testing
- Treatment A: Azelastine hydrochloride 0.15% nasal spray (Azelair), Treatment C: Ryaltris (Active Control) - mometasone furoate monohydrate and olopatadine hydrochloride nasal spray
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Rhinitis, Allergic, Seasonal, Hay Fever
Methylprednisolone Injections Treating Birch Pollen Induced Allergic Rhinitis.
This study evaluates the effect of intramuscular injected methylprednisolone treating birch pollen induced rhinitis compared to placebo.
- Conditions
- Rhinitis, Allergic, Seasonal, Hay Fever, Pollen Allergy, Allergic Rhinitis
- Trial name
- NCT04622917
- Testing
- MethylPREDNISolone 40 Mg/mL Injectable Suspension, NaCl 9 MG/ML Injectable Solution
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Allergy to House Dust, Allergy Pollen
Validation and Reproducibility of S.P.A.T. With Allergens
To improve accuracy and take out human error opportunities, Hippo Dx developed S.P.A.T., an automated skin prick test. This study will provide a comparison between manual and automated skin prick test in allergic and non-allergic…
- Trial name
- NCT05824637
- Testing
- Skin Prick Automated Test, Skin Prick Manual Test
- Where
- Belgium
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hippocreates
Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis
Bioequivalence Study of Azelastine Hydrochloride/ Fluticasone Propionate 137 Microgram/50 Microgram Nasal Spray and Dymista Nasal Spray
Single dose (four sprays) bioequivalence study of Azelastine Hydrochloride/ Fluticasone Propionate 137 microgram/50 microgram Nasal Spray and 'DYMISTA' (Azelastine Hydrochloride/Fluticasone Propionate) Nasal Spray 137…
- Trial name
- NCT06180083
- Testing
- Azelastine Hydrochloride/ Fluticasone propionate nasal spray, 'DYMISTA' NASAL SPRAY
- Where
- India
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Allergic Rhinoconjunctivitis, Perennial Allergic Rhinitis
Efficacy and Safety Evaluation for the Treatment of Asthma and Allergic Rhinitis/Rhinoconjunctivitis
Prospective, randomized, placebo-controlled, multicenter of 3 active treatment groups, compared to 1 placebo group, for the determination of the efficacy and safety of subcutaneous immunotherapy in patients with mild to moderate…
- Conditions
- Allergic Rhinoconjunctivitis, Perennial Allergic Rhinitis, House Dust Mite Allergy, Pollen Allergy
- Trial name
- NCT04874714
- Testing
- MM09-MG01(30.000-30.000), MG01(30.000), MM09(30.000)
- Where
- 13 sites in Spain
- Volunteers
- 18 people
- Sponsor
- Inmunotek S.L.
Seasonal Allergic Rhinitis
Study of CM310 in Subjects With Seasonal Allergic Rhinitis
This study is a multicenter, single arm phase II clinical study mainly evaluating the efficacy of CM310 in patients with seasonal allergic rhinitis.
- Trial name
- NCT06171074
- Testing
- CM310
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Keymed Biosciences Co.Ltd
Seasonal Allergic Rhinitis
To Investigate Drug-drug Interaction and Relative Bioavailability Between the FDC AzelastineHCL/Beclomethasone Dipropionate Nasal Spray, & Beclomethasone Dipropionate Nasal Spray in the Test Vehicle, and RinoClenil® Nasal Spray
An open label, randomized, three-treatment, three-period, crossover, single dose study, to investigate drug-drug interaction and relative bioavailability between the fixed dose combination Azelastine hydrochloride /…
- Trial name
- NCT04817800
- Testing
- 140/100 μg Azelastine hydrochloride/Beclomethasone Dipropionate)
- Where
- Jordan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Allergy, Allergy;Food
Allergy Diagnostic Test Based on Microchip Technology
The purpose of this study is to develop a microarray-based diagnostic test system for the determination of allergen specific IgE in human blood serum.
- Conditions
- Allergy, Allergy;Food, Allergy Pollen, Allergy Drug
- Trial name
- NCT06167564
- Testing
- Routine allergy tests, Newly developed microarray-based diagnostic test system
- Where
- Belarus
- Volunteers
- 400 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Allergic Conjunctivitis, Seasonal Allergies
A Safety and Activity Study of NS2 in Subjects With Allergic Conjunctivitis
This is a randomized, parallel, single center, double masked, vehicle controlled study. The purpose of this study is to determine the activity and safety of NS2 in patients with grass, tree or ragweed-pollen induced seasonal…
- Trial name
- NCT02578914
- Testing
- NS2 Ophthalmic Drops (0.5%), NS2 Ophthalmic Drops Vehicle (0.0%)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Allergic Rhinitis Due to Pollen, Allergic Rhinitis With Asthma
Interaction Between Air Pollution, Pollens and Allergic Rhinitis
Seasonal allergic rhinitis has multiple consequences: sleep disturbances, fatigue, depressed mood, impaired quality of life and productivity, and co-morbid conditions such as asthma, which affects one third of AR patients.
- Trial name
- MISTRAL (NCT05007327)
- Testing
- Exposure to pollen and air pollution
- Where
- France
- Volunteers
- 1,215 people
- Sponsor
- MASK-air SAS
Seasonal Allergic Rhinitis
Study to Compare the Pharmacokinetics of Fixed-Dose Combination of Mometasone + Azelastine Nasal Spray to Mometasone and Azelastine Nasal Sprays in Adolescents and Young Adults With Seasonal Allergic Rhinitis
This study will compare the PK parameters of the combination test formulation to monotherapy reference products (mometasone furoate and azelastine hydrochloride) in adolescents and young adult patients with seasonal allergic…
- Trial name
- NCT05887843
- Testing
- Mometasone + Azelastine, Mometasone Furoate, Azelastine Hydrochloride
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Sandoz
Rhinitis, Allergic, Seasonal
Grass Pollen Immunotherapy Using a Cluster Regime for Seasonal Rhinitis and Asthma
The purpose of this study was to assess the effects of grass pollen immunotherapy on symptoms, bronchial hyperresponsiveness and quality of life in seasonal rhinitis and asthma.
- Trial name
- NCT00135642
- Testing
- Subcutaneous Alutard SQ grass pollen (Phleum pratense), Venepuncture: 20 ml blood sample taken on 2 separate visits
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Imperial College London
Hayfever
Repeat Nasal Allergen Challenge
This is a non-drug, biomarker study to assess the utility of the model of repeated nasal allergen challenges in subjects with atopic rhinitis as a method of inducing an increased response to inhaled allergen, which will more…
- Trial name
- NCT00290368
- Testing
- Skin Prick Test, Nasal allergen challenge, Nasal filter paper placement
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Seasonal Allergic Rhinitis
Efficacy and Safety of Azelastine +Mometasone , Nasal Spray, 140 mcg + 50 mcg, (Sandoz d.d., Slovenia) and Momat Rino Advance, Nasal Spray, 140 mcg + 50 mcg, (Glenmark, India) Administered as a Monotherapy to Patients With Seasonal Allergic Rhinitis.
Prospective, multicenter, open, randomized, parallel, clinical study for assessment of comparative efficacy and safety of Azelastine +Mometasone Sandoz (main group) and Momat Rino Advance (control group) administered as a…
- Trial name
- NCT05590598
- Testing
- Azelastine + Mometazone, nasal spray, Momat Rhino Advance
- Where
- 15 sites in Russia
- Volunteers
- 472 people
- Sponsor
- Sandoz