Clinical trials: Rhinitis
Rhinitis, Allergic, Perennial
A Study of Mometasone Furoate Nasal Spray in Perennial Allergic Rhinitis (Study P03748)(COMPLETED)
This is a multicenter, randomized, double-blind within the dose level, parallel group comparison of mometasone furoate nasal spray in subjects with perennial allergic rhinitis to examine the minimal effective dose, the…
- Trial name
- NCT00779545
- Testing
- Mometasone furoate
- Volunteers
- 455 people
- Sponsor
- Organon and Co
Atopy, Rhinitis
Effect of an Immunotoxin on Activated Human Macrophages in Those With Allergic Rhinitis or Mild Intermittent Asthma
The primary objective of this study is to isolate macrophages by using bronchoalveolar lavage (BAL) for different in vitro experiments.
- Conditions
- Atopy, Rhinitis, Bronchial Asthma
- Trial name
- NCT00295737
- Testing
- bronchoscopy, allergen/endotoxin instillation
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Seasonal Allergic Rhinitis
A Study Investigating the Effect of Montelukast in Patients With Seasonal Allergic Rhinitis (MK-0476-192)(COMPLETED)
A study of the ability of montelukast to improve signs and symptoms of seasonal allergic rhinitis compared with placebo. Loratadine is included in the study as an active control.
- Trial name
- NCT00960141
- Testing
- montelukast sodium, Comparator: loratadine
- Volunteers
- 829 people
- Sponsor
- Organon and Co
Allergic Rhinitis, House Dust Mite Allergy
AZELASTINE/FLUTICASONE (AZE/FLU) Nasal Spray on Symptom Control, Nasal Mediators and Nasal Hyperresponsiveness in Allergic Rhinitis (AR)
Comparative analysis of the efficacy of intranasal MP29-02 (a novel formulation of azelastine and FP) has already been conducted in patients with moderate-to-severe seasonal AR.
- Trial name
- NCT02238353
- Testing
- azelastine + fluticasone
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Allergic Rhinitis Due to Grass Pollen, Allergic Asthma
Kinetics of Nasal Cytokine Responses to Mechanical Stimulation
IgE-associated allergy is a hypersensitivity disease affecting more than 40% of the population in industrialised countries. Recently the kinetics of change of clinical and immunological parameters (e.g.
- Trial name
- NCT04878237
- Testing
- Nasal Secretion Sampling
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy, Allergic Rhinitis
Tolerability/Safety of Intranasal AZD8848 in Healthy Male Volunteers and Seasonal Allergic Rhinitis Male Patients Out of Season
Investigate safety/tolerability after a single dose intranasal administration of AZD8848 comparator placebo to healthy male volunteers and seasonal allergic rhinitis male patients out of season
- Trial name
- SAD (NCT00688779)
- Testing
- AZD8848
- Where
- Sweden
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Non-allergic Rhinitis
Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis
Chronic rhinitis is affecting more than 200 million people worldwide. Its prevalence is estimated to be as high as 30% of the Western population.
- Trial name
- NCT02288156
- Testing
- Capsaicin
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Allergic Rhinitis
The Dysbiosis of the Intestinal Microbiota in Individuals With Allergic Rhinitis (MICRORIN)
Allergic rhinitis (AR) is triggered by environmental allergens such as pollen and mites, and is associated with several symptoms such as itching and nasal congestion, sneezing or tearing and redness of the eyes.
- Trial name
- MICRORIN (NCT03946553)
- Where
- Spain
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Perennial Allergic Rhinitis, PAR
A Safety and Efficacy Study of Ciclesonide Nasal Aerosol in Subjects 6-11 Years With Perennial Allergic Rhinitis (PAR).
This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group, efficacy and safety study of ciclesonide nasal aerosol administered once daily to male and premenarchal female subjects 6 to 11 years…
- Trial name
- NCT01451541
- Testing
- Ciclesonide nasal aerosol 37 mcg, ciclesonide nasal aerosol 74 mcg
- Where
- 60 sites in United States
- Volunteers
- 848 people
- Sponsor
- Sumitomo Pharma America, Inc.
Nonallergic Irritant Rhinitis
Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis
The proposed study seeks to investigate the effect of intranasal capsaicin treatment in patient with Non-allergic irritant rhinitis (NAIR), as well as evaluate optical rhinometry (ORM) as a means to quantify symptomatic…
- Trial name
- NCT02493257
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Allergic Rhinitis, Asthma
Randomized Evaluation of Ten Allergy Skin Prick Test Devices
The goal of this study is to compare ten current and readily available FDA approved allergy skin prick devices to determine the most sensitive and specific product and methods used for the diagnosis of allergic disease.
- Conditions
- Allergic Rhinitis, Asthma, Food Allergy, Skin Testing
- Trial name
- NCT03509766
- Testing
- Histamine skin testing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Allergic Reaction, Allergic Skin Reaction
Quercus Ilex and Quercus Robur Allergen Extracts Standardisation
The objective of this study is to determine the biological activity of Quercus illex and Quercus robur allergen extracts in histamine equivalent prick (HEP) units, in order to be used as in-house reference preparation (IHRP).
- Conditions
- Allergic Reaction, Allergic Skin Reaction, Allergy Pollen
- Trial name
- NCT05532566
- Testing
- Allergenic extract
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Inmunotek S.L.
Seasonal Allergic Rhinitis
Study to Compare the Pharmacokinetics of Fixed-Dose Combination of Mometasone + Azelastine Nasal Spray to Mometasone and Azelastine Nasal Sprays in Adolescents and Young Adults With Seasonal Allergic Rhinitis
This study will compare the PK parameters of the combination test formulation to monotherapy reference products (mometasone furoate and azelastine hydrochloride) in adolescents and young adult patients with seasonal allergic…
- Trial name
- NCT05887843
- Testing
- Mometasone + Azelastine, Mometasone Furoate, Azelastine Hydrochloride
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Sandoz
Allergic Asthma, Bronchial Inflammation
Fish Oil and Asthma in House Dust Mite Allergy
Native populations consuming high amounts of fish suffer less from allergic diseases. The purpose of this study is to determine whether polyunsaturated fatty acids (fish oil) might have a disease modifying influence on asthmatics…
- Conditions
- Allergic Asthma, Bronchial Inflammation, House Dust Mite Allergy
- Trial name
- NCT00380926
- Testing
- polyunsatturated fatty acids (fish oil)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Mite Allergy, Dermatophagoides Farinae Allergy
Retrospective Study Evaluating the Effectiveness and Safety of Immunotherapy With Clustoid Max Forte
House dust mites are the main source of allergies in indoor environments. They are predominant in coastal areas, with the Canary Islands being the autonomous community with the highest percentage of patients with…
- Conditions
- Mite Allergy, Dermatophagoides Farinae Allergy, Dermatophagoides Pteronyssinus Allergy, Rhinitis, Allergic
- Trial name
- NCT07427576
- Testing
- Clustoid® Max Forte
- Where
- 2 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Inmunotek S.L.
Seasonal Allergic Rhinitis
Study of CM310 in Subjects With Seasonal Allergic Rhinitis
This study is a multicenter, single arm phase II clinical study mainly evaluating the efficacy of CM310 in patients with seasonal allergic rhinitis.
- Trial name
- NCT06171074
- Testing
- CM310
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Keymed Biosciences Co.Ltd
Severe Asthma, Allergy to House Dust Mites
Potency of HDM Sublingual AIT Tablets in Assuring the Persistency of Asthma Control in HDM Allergic Patients With Severe Asthma, Treated With Tezepelumab
The aim of this drug trial is to evaluate the annualized asthma exacerbation rate under treatment with Acarizax versus placebo. The trial is intended for adults aged 18 to 65 with severe uncontrolled asthma and a house dust mite…
- Trial name
- TEZEPAIT (NCT07013123)
- Testing
- Tezepelumab, Acarizax
- Volunteers
- 38 people
- Sponsor
- University Hospital, Montpellier
Allergic Rhinitis
The Effect of Early Radiofrequency Turbinate Reduction on Persistent Allergic Rhinitis
The primary outcome of this study is to evaluate the effect of radiofrequency turbinate reduction as an initial treatment on clinical improvement (using visual analogue scale based on total nasal symptoms score, peak nasal…
- Trial name
- NCT05276336
- Testing
- Radiofrequency turbinate reduction, Pharmacology treatment
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Perennial Allergic Rhinoconjunctivitis, House Dust Mite Allergy
A Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivitis
The purpose of the study is to test the efficacy of the combination treatment AllQbG10 in patients with perennial allergic rhinoconjunctivitis due to house dust mite allergy in a double-blind, placebo-controlled setting
- Trial name
- NCT00574704
- Testing
- CYT005-AllQbG10 (combination of house dust mite allergen extract with CYT003-QbG10)
- Volunteers
- 40 people
- Sponsor
- Cytos Biotechnology AG
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia