Clinical trials: Rhinitis Allergic
Seasonal Allergic Rhinitis (SAR)
Efficacy and Safety of GSP 301 Nasal Spray in Children (Aged 6 to Under 12 Years) With Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy, safety and tolerability of GSP 301 nasal spray (NS) compared with placebo NS in pediatric subjects (aged 6 to under 12 years) with Seasonal Allergic Rhinitis (SAR).
- Trial name
- GSP 301-305 (NCT03463031)
- Testing
- GSP 301 NS
- Where
- 32 sites in United States
- Volunteers
- 446 people
- Sponsor
- Glenmark Specialty S.A.
Pruritus, Chronic Urticaria
Safety Study of Levocetirizine and Fexofenadine
This Study is to comparison of Efficacy and Consistency of Action of Levocetirizine 5 mg once daily with Fexofenadine 60 mg twice daily in the histamine induced wheal, flare and itch Response.
- Conditions
- Pruritus, Chronic Urticaria, Allergic Rhinitis
- Trial name
- LAWAF (NCT01586091)
- Testing
- Levocetirizine Oral Tablet, Fexofenadine 60 Mg Oral Tablet
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Efficacy and Safety of SUBLIVAC Phleum for Immunotherapy of Grass Pollen-Allergy
The purpose of this study is to assess safety, tolerability and demonstrate a dose response signal using Total Symptom Score (TSS), based on challenges with grass pollen in an Environmental Exposure Chamber (EEC), followed by…
- Trial name
- NCT02556801
- Testing
- SUBLIVAC FIX Phleum Prat.
- Where
- Canada
- Volunteers
- 168 people
- Sponsor
- HAL Allergy
Rhinitis, Allergic, Seasonal
Efficacy and Safety Study of RAGWITEK™ (MK-3641) in Children With Ragweed-Induced Rhinoconjunctivitis With or Without Asthma (MK-3641-008)
The purpose of this study is to assess the efficacy and safety of short ragweed pollen allergen extract (MK-3641, SCH 039641, RAGWITEK™) sublingual immunotherapy tablets in children aged 5 to 17 years with ragweed-induced…
- Trial name
- NCT02478398
- Testing
- Short ragweed pollen allergen extract, Self-injectable epinephrine, Albuterol/Salbutamol
- Volunteers
- 1,025 people
- Sponsor
- Merck Sharp & Dohme LLC
Allergic Rhinitis
A Novel Biologic Therapy for Perennial Allergic Rhinitis
This is a randomized, parallel-group, double-blind, phase 2, single center, proof-of-concept study which will evaluate the effect of a preparation of FDA approved allergens (PMA) used as a sub-cutaneously administered…
- Trial name
- NCT03360071
- Testing
- Allergen Immunotherapy Extract, Allergen Immunotherapy Control
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Johns Hopkins University
Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis
The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis
The goal of this research project is to explore the impact of the addition of budesonide to high-volume, low-pressure nasal sinus saline irrigation (aka "Neti-Pot"-type systems) for patients with chronic rhinosinusitis with or…
- Conditions
- Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis, Allergic Rhinosinusitis
- Trial name
- NCT02696850
- Testing
- Budesonide, Saline alone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Washington University School of Medicine
Rhinitis, Allergic, Seasonal
Drug Utilization Study for Pirinase Hayfever Relief
The purpose is to obtain real-world information on how consumers are complying with the product labelling This study will coincide with the launch of Pirinase Hayfever Relief for Adults 0.05% Nasal Spray in the United Kingdom…
- Trial name
- NCT02856282
- Testing
- Pirinase Hayfever Relief for Adults 0.05% Nasal Spray
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
Efficacy and Safety of SPARC1310 in Seasonal Allergic Rhinitis
The study will assess the efficacy and safety of SPARC1310 when compared to placebo and active control
- Trial name
- NCT01940146
- Testing
- SPARC1310 I, SPARC1310 II, SPARC1310 III
- Where
- Canada
- Volunteers
- 222 people
- Sponsor
- Sun Pharma Advanced Research Company Limited
Allergic Rhinitis
Comparability and Standardization of Controlled Allergen Challenge Facilities
Allergen challenge facilities have been utilized for many years in clinical drug trials studying onset of action, proof of concept, duration of action, and efficacy.
- Trial name
- NCT02543346
- Testing
- Cetirizine
- Where
- 2 sites in United States, Canada
- Volunteers
- 98 people
- Sponsor
- Queen's University
Allergic Rhinitis
A Study of the Effects of Single Dose Corticosteroids on Response to Allergens
This study will investigate whether changes in inflammatory mediators produced by the nose after exposure to an allergen can be used to evaluate the anti-inflammatory effects of novel drugs for the treatment of allergic asthma.
- Trial name
- NCT00828061
- Testing
- prednisone
- Volunteers
- 19 people
- Sponsor
- Merck Sharp & Dohme LLC
Allergic Rhinitis, Allergic Rhinoconjunctivitis
MK-8237 (SCH900237) Biomarker Study in Participants With Allergic Rhinitis or Rhinoconjunctivitis (MK-8237-009)
The purpose of this study is to assess the effect on various biomarkers of treatment with MK-8237 in participants with allergic rhinitis or rhinoconjunctivitis.
- Trial name
- NCT01852825
- Testing
- MK-8237, NAC
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Asthma, Allergic Rhinitis
Nasal Allergen Challenge in Rhinitic Subjects
Background: Nasal allergen challenge (NAC) is useful to study the pathophysiology of rhinitis, and multiple challenges may more adequately approximate natural exposure.
- Trial name
- NCT01286129
- Testing
- Nasal allergen challenge
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Laval University
Seasonal Allergic Rhinitis
Efficacy and Safety of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy and safety of GSP 301 NS compared to placebo NS and to individual monotherapies (comparators) as well as the efficacy of these monotherapies (comparators) versus placebo NS over 14 days of study…
- Trial name
- GSP 301-301 (NCT02631551)
- Testing
- GSP 301 NS, Olopatadine HCl NS, Mometasone furoate NS
- Where
- 37 sites in United States
- Volunteers
- 1,180 people
- Sponsor
- Glenmark Specialty S.A.
Rhinitis, Allergic
A Study to Compare the Efficacy of Levocetirizine to Placebo in Reducing Symptoms of Seasonal Allergic Rhinitis (SAR) in Sensitive Subjects Exposed to Ragweed Pollen
The purpose of the study is to assess the efficacy comparability of cetirizine and levocetirizine, by comparing the effects of single intake of the two drugs to placebo in reducing symptoms of seasonal allergic rhinitis (SAR) in…
- Conditions
- Rhinitis, Allergic, Seasonal
- Trial name
- NCT00291642
- Testing
- Levocetirizine drops, Levocetirizine tablets
- Where
- Canada
- Volunteers
- 551 people
- Sponsor
- UCB Pharma
Rhinitis, Allergic, Seasonal
Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects
To compare the clinical efficacy of levocetirizine 5 mg and montelukast 10 mg on symptoms of seasonal allergic rhinitis occurring in subjects exposed to ragweed pollen in an environmental exposure unit.
- Trial name
- NCT00295022
- Testing
- Montelukast, Levocetirizine
- Where
- Canada
- Volunteers
- 418 people
- Sponsor
- UCB S.A. - Pharma Sector
Rhinitis, Allergic, Seasonal
A 5-way Treatment Period Trial of Single Doses of Intranasal GSK256066 in Patients With Rhinitis
This current study is planned as a dedicated pharmacodynamic (effect of drug on the body) study to investigate the dose response in rhinitic subjects at doses where GSK256066 has been proven to work (200mcg) or expected to…
- Trial name
- NCT00464568
- Testing
- GSK256066
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis, Asthma
Randomized Evaluation of Ten Allergy Skin Prick Test Devices
The goal of this study is to compare ten current and readily available FDA approved allergy skin prick devices to determine the most sensitive and specific product and methods used for the diagnosis of allergic disease.
- Conditions
- Allergic Rhinitis, Asthma, Food Allergy, Skin Testing
- Trial name
- NCT03509766
- Testing
- Histamine skin testing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Rhinitis, Allergic, Perennial and Seasonal
A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis
This phase IV investigational trial is being conducted to evaluate the efficacy of a 2-week treatment of fluticasone propionate nasal spray (FPNS) vs.
- Trial name
- NCT01916226
- Testing
- FPNS, Cetirizine
- Where
- 31 sites in United States
- Volunteers
- 682 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis
The hypothesis is that treating hay fever patients who had daytime sleepiness and slowed thinking because of the hay fever will improve when treated with an effective anti-hay fever medication, an intranasal steroid, that is will…
- Trial name
- NCT00997620
- Testing
- Fluticasone furoate Nasal Spray 110 mcg
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Western Sky Medical Research
Rhinitis, Allergic, Perennial
Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR)
The primary objective of this study is to compare the efficacy and safety of GW685698X 100mcg once daily (QD) aqueous nasal spray with vehicle placebo nasal spray in adult and adolescent subjects (12 years of age and older) with…
- Trial name
- NCT00289198
- Testing
- FF
- Where
- 42 sites in United States, Australia and 7 more
- Volunteers
- 301 people
- Sponsor
- GlaxoSmithKline