Clinical trials: Rhinitis Seasonal
Rhinitis, Allergic, Seasonal
Mometasone Furoate Aqueous (MK-0887/SCH 032088) Nasal Spray vs Placebo and FLONASE® in Seasonal Allergic Rhinitis Patients (I94-001)
The purpose of this study is to evaluate the efficacy and safety of mometasone furoate (SCH 32088) aqueous nasal spray 200 mcg once daily compared to placebo once daily in the treatment of participants with seasonal allergic…
- Trial name
- NCT03882047
- Testing
- Mometasone furoate, Fluticasone propionate
- Volunteers
- 313 people
- Sponsor
- Organon and Co
Type I Hypersensitivity
Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis
Tree MATAMPL has been developed to provide pre-seasonal specific immunotherapy for patients with hypersensitivity to Tree (birch, alder, hazel) pollen (hay fever).
- Trial name
- NCT00387478
- Testing
- Tree MATA MPL or Tree MATA
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- Allergy Therapeutics
Seasonal Allergic Rhinitis
A Clinical Pharmacology Study of MT-2990 in Seasonal Allergic Rhinitis Patients
The objective of this study is to investigate the safety, tolerability, and pharmacokinetics of MT-2990 in patients with Japanese cedar pollen-induced seasonal allergic rhinitis (JC-SAR).
- Trial name
- NCT03570957
- Testing
- MT-2990
- Where
- Japan
- Volunteers
- 75 people
- Sponsor
- Tanabe Pharma Corporation
Seasonal Allergic Rhinitis
Vienna Challenge Chamber Study Using RV658 in Subjects With Allergic Rhinitis
RV568 is being developed for the treatment of diseases such as asthma, COPD and allergic rhinitis (e.g. hayfever). The main aim of this study is to investigate whether RV568 ameliorates the nasal symptoms to low doses of grass…
- Trial name
- NCT01230619
- Testing
- RV568
- Where
- Austria
- Volunteers
- 75 people
- Sponsor
- Respivert Ltd
Seasonal Allergic Rhinoconjunctivitis
Safety Study of Grass Pollen-derived Peptides to Treat Seasonal Allergic Rhinoconjunctivitis
The purpose of this study is to determine whether the oral administration of grass pollen peptides is safe and effective in the treatment of allergic rhinitis.
- Trial name
- NCT00833066
- Testing
- gpASIT+TM
- Where
- 4 sites in Belgium
- Volunteers
- 54 people
- Sponsor
- BioTech Tools S.A.
Allergic Rhinitis, Chronic Urticaria
Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less Than 6 Years Suffering From Allergic Rhinitis or Chronic Urticaria of Unknown Origin
The purpose of this study is to determine the safety of the oral formulation of levocetirizine in children ages 1 to less than 6 years old who suffer from allergic rhinitis or chronic urticaria of unknown origin.
- Trial name
- PAL (NCT00619801)
- Testing
- Levocetirizine
- Where
- 28 sites in United States
- Volunteers
- 173 people
- Sponsor
- UCB Pharma
Rhinitis, Allergic, Seasonal, Hay Fever
A Study of Ciclesonide Nasal Spray in Patients 18 Years and Older With Seasonal Allergic Rhinitis (BY9010/M1-413)
The purpose of this study is to investigate the safety and effectiveness of ciclesonide nasal spray as compared with placebo (inactive substance) nasal spray in relieving symptoms of seasonal allergic rhinitis caused by pollen.
- Trial name
- NCT00384475
- Testing
- Ciclesonide Nasal Spray
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis
Preference for Clarinex Tablets vs. Zyrtec Tablets in Patients With Allergies (P03182)
This was a crossover study designed to see if patients with allergy symptoms preferred Clarinex® or Zyrtec®. Patients were randomized to take 7 days of Clarinex or Zyrtec treatment, followed by a 5 to 28-day washout period (days…
- Trial name
- NCT00794599
- Testing
- Desloratadine 5 mg (Clarinex), Cetirizine (Zyrtec)
- Volunteers
- 118 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Preference for Clarinex Tablets vs. Allegra Tablets in Patients With Seasonal Allergies (Study P03179)
This was a crossover study designed to see if patients with seasonal allergy symptoms preferred Clarinex® or Allegra®. Patients were randomized to take 7 days of Clarinex or Allegra treatment, followed by a 5 to 28-day washout…
- Trial name
- NCT00794248
- Testing
- desloratadine 5 mg, fexofenadine
- Volunteers
- 122 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis, Hay Fever
Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic Treatment of SAR
Evaluate the relative efficacy of four dosing regimens of bilastine tablets (given either once or twice per day) versus placebo in patients with Seasonal Allergic Rhinitis (SAR) in the Mountain Cedar season in south Texas and…
- Conditions
- Seasonal Allergic Rhinitis, Hay Fever, Allergic Conjunctivitis, Hypersensitivity
- Trial name
- NCT00574379
- Testing
- Bilastine
- Where
- 13 sites in United States
- Volunteers
- 805 people
- Sponsor
- Faes Farma, S.A.
Post-nasal Drip, Seasonal Allergic Rhinitis
Desloratadine With Oxybutynin for the Treatment of Seasonal Allergic Rhinitis and Post-Nasal Drip (Study P04258)(COMPLETED)
This was a 1-week study of desloratadine (DL) plus oxybutynin (OXY) at two dose levels in the treatment of post-nasal drip in participants with seasonal allergic rhinitis.
- Conditions
- Post-nasal Drip, Seasonal Allergic Rhinitis, Rhinorrhea
- Trial name
- NCT00816972
- Testing
- Desloratadine 2.5 mg, Oxybutynin 2.5 mg
- Volunteers
- 540 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05529)
This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Trial name
- NCT00732381
- Testing
- Mometasone furoate nasal spray (MFNS)
- Volunteers
- 351 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Study of Efficacy and Safety of Omalizumab in Severe Japanese Cedar Pollinosis Adult and Adolescent Patients
The purpose of this study was to demonstrate the efficacy and safety of omalizumab compared with placebo, on top of SoC (anti-histamine and nasal corticosteroid) in adult and adolescent patients with severe Japanese cedar…
- Trial name
- NCT03369704
- Testing
- Omalizumab
- Where
- 22 sites in Japan
- Volunteers
- 337 people
- Sponsor
- Novartis Pharmaceuticals
Allergic Rhinitis
Safety and Efficacy Study of PA9159 Nasal Spray for the Treatment of Seasonal Allergic Rhinitis
PA9159 is a highly potent novel corticosteroid. The purpose of this study is to evaluate the safety, efficacy and characteristics of population pharmacokinetics of multiple dosing of PA9159 Nasal Spray in patients with seasonal…
- Trial name
- NCT05234580
- Testing
- PA9159 nasal spray solution, 10 μg once daily for 14 days, PA9159 nasal spray solution, 20 μg once daily for 14 days, PA9159 nasal spray solution, 40 μg once daily for 14 days
- Where
- 17 sites in China
- Volunteers
- 204 people
- Sponsor
- Anhui Palo Alto Pharmaceuticals, Inc.
Seasonal Allergic Rhinitis
Efficacy and Safety of Fixed Dose Combination (FDC) of Olopatadine Hydrochloride and Mometasone Furoate Nasal Spray (Molo; Also Referred as GSP 301) in the Treatment of Seasonal Allergic Rhinitis (SAR)
A single-center, double-blind, placebo-controlled study of FDC olopatadine hydrochloride and mometasone furoate nasal spray (Molo; also referred as GSP 301) was conducted in subjects with seasonal allergic rhinitis.
- Trial name
- GSP 301- PoC (NCT03444506)
- Testing
- Molo 1 (also referred as GSP 301-2 NS), Molo 2 (also referred as GSP 301-1 NS), DYMISTA nasal spray
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Seasonal Allergic Rhinitis
Clinical Equivalence Study of Mometasone Nasal Spray, 50 Mcg/Actuation
The objective of this study is to evaluate the clinical equivalence of the test formulation of mometasone furoate anhydrous 50 mcg/actuation nasal spray (manufactured by Teva Pharmaceutical Industries, Ltd.
- Trial name
- NCT01523236
- Testing
- Mometasone furoate, Nasonex®
- Volunteers
- 800 people
- Sponsor
- Teva Pharmaceuticals USA
Rhinitis, Allergic, Seasonal
723/726 Proof of Concept Study in Allergen Challenge Chamber in Hannover
This is a randomised, double-blind, placebo-controlled 4-period cross-over study to assess the efficacy and safety of repeat dose intranasal GSK1004723 (1000µg), oral GSK835726 (10mg) and cetirizine (10mg) in the environmental…
- Trial name
- NCT00972504
- Testing
- GSK835726 10mg, GSK1004723 1000mcg, Cetirizine 10mg
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- GlaxoSmithKline
Birch Pollen-Related Rhinoconjunctivitis, Rhinitis, Allergic, Seasonal
Safety and Tolerability Study of rBet v1 SLIT Tablets
The purpose of this study is to determine the safety and tolerability of several doses of r Bet v1 administered as sub-lingual tablets in subjects sensitised to birch pollen.
- Trial name
- NCT00889460
- Testing
- rBet v 1
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Stallergenes Greer
Seasonal Allergic Rhinitis
Trial of STAHIST in Seasonal Allergic Rhinitis
The overall development plan is to show that the combination of tried-and-proven decongestant/antihistamine ingredients (pseudoephedrine hydrochloride and chlorpheniramine maleate), plus a very small amount of belladonna…
- Trial name
- NCT01293201
- Testing
- STAHIST
- Where
- 8 sites in United States
- Volunteers
- 290 people
- Sponsor
- Magna Pharmaceuticals, Inc.
Rhinitis, Allergic, Seasonal
Single and Repeat Dose First Time in Human Study for an Intranasal H1/H3 Dual Antagonist in Healthy Male Subjects
This is a double-blind, placebo-controlled, randomized single dose escalation study and a double-blind, placebo-controlled, randomised parallel group 14-days once daily repeat dose study to investigate safety, tolerability and…
- Trial name
- NCT00694993
- Testing
- GSK1004723
- Where
- Germany
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline