Clinical trials: Rhinovirus Infection
Enterovirus, Rhinovirus
Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Colds Due to Enterovirus/Rhinovirus Infection
Trial to evaluate the efficacy and safety of nitazoxanide in the treatment of colds due to enterovirus/rhinovirus infection
- Trial name
- NCT04489381
- Testing
- Nitazoxanide, Vitamin Super B-Complex
- Where
- 3 sites in United States
- Volunteers
- 214 people
- Sponsor
- Romark Laboratories L.C.
Asthma, Allergic Rhinitis
Clinical Response to Rhinovirus Challenge
Rhinovirus (RV) infections represent the most common cause of asthma exacerbations in children and adolescents. The investigators hypothesize that the immune responses generated in the nose of allergic rhinitics and asthmatics…
- Trial name
- NCT02910401
- Testing
- Rhinovirus (GMP RV16 HRV-16)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Asthma, Inflammation
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing
The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection, stratified by rhinovirus…
- Trial name
- INSTAR (NCT03889743)
- Testing
- Dexamethasone treatment during 3 days
- Where
- 8 sites in Finland, Norway and 1 more
- Volunteers
- 280 people
- Sponsor
- St. Olavs Hospital
Common Cold
Clinical Trial to Optimise Levels of Vitamin D for Rhinovirus Protection
A phase II randomised, placebo-controlled trial to identify the optimal regimen of vitamin D supplementation for rhinovirus protection, determined by host responses to a clinically induced rhinovirus challenge.
- Trial name
- NCT04368520
- Testing
- Vitamin D3
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Asthma
Effect of Montelukast on Experimentally-Induced RV16 Infection in Asthma
People with asthma may have asthma worsening when they have an upper respiratory infection due to a virus or a common cold. Leukotrienes are increased in nasal secretions from children with Respiratory Syncytial Virus (RSV) and…
- Trial name
- NCT00359073
- Testing
- montelukast
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Wisconsin, Madison
Healthy Volunteers
Hallmarks of Protective Immunity in Sequential Rhinovirus Infections in Humans
The primary objective of this study is to assess the relationship between rhinovirus specific T-cell immunity and the human host response to primary rhinovirus challenge and subsequent secondary challenge with either homologous…
- Trial name
- NCT02796001
- Testing
- human rhinovirus, no intervention
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Virginia