Clinical trials: Rhythm
Obesity
The Effect of Circadian Timing Program on Obesity Management and Sleep Quality
This study, it was aimed to examine the effect of circadian timing program created for obese individuals with evening chronotype on obesity management and sleep quality.
- Trial name
- NCT04665336
- Testing
- Circadian Timing Program, Sleep Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Kocaeli University
Atrial Fibrillation
Early Atrial Fibrillation Ablation for Stroke Prevention in Patients With High Comorbidity Burden (EASThigh-AFNET 11)
EASThigh-AFNET 11 is an international, prospective, randomized, open, blinded endpoint assessment, multicenter trial (Treatment Strategy trial).
- Trial name
- NCT06324188
- Testing
- Early atrial fibrillation ablation, Usual Care
- Where
- 7 sites in Australia, Canada and 5 more
- Volunteers
- 2,312 people
- Sponsor
- Atrial Fibrillation Network
Heart Rhythm Disorder, Covid19
Effect of Social Isolation on Physical Activity Level, and Kinesophobia in Heart Rhythm Disorders During Pandemic
The aim of our study is to examine the effect of social isolation on physical activity level, health literacy and kinesophobia in heart rhythm disorders.
- Conditions
- Heart Rhythm Disorder, Covid19, Social Isolation
- Trial name
- NCT04818697
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Traditional Chinese Medicine, Insomnia
Insomnia Treated by Traditional Chinese Medicine and Its Circadian Rhythm
Insomnia and sleep disorders are prominent health problems in modern society. High working pressure, fast pace of life, the use of electronic products and other reasons lead to the high incidence of insomnia and sleep disorders…
- Conditions
- Traditional Chinese Medicine, Insomnia, Circadian Rhythm
- Trial name
- NCT04448197
- Testing
- Chinese Medicine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Rheumatoid Arthritis
RHYTHM (Formerly Escape II Myocardium)
For aim 1, the proposed studies will be performed in 150 patients with RA and 25 subjects without RA (healthy volunteers) who will function as controls.
- Trial name
- RHYTHM (NCT01548768)
- Testing
- TNF inhibitors, DMARDs
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Columbia University
Binge-Eating Disorder
Use of Circadian Reset Technology to Alter REM Sleep and Appetitive Control in Patients With Binge Eating Disorder
This project includes testing circadian reset technology (CRT) on frequency of binge eating in a sample of 40 individuals with binge eating disorder. Participants will be randomized to one of two groups.
- Trial name
- NCT06858774
- Testing
- Circadian Reset Technology, VR Headset
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Sleep, Sleep Disorders, Circadian Rhythm
Effects of Delayed School Start Times on Sleep, Mental Health, and Academic Performance Among Norwegian Adolescents
The aim is to investigate whether later school start times have positive effects on high school students' sleep patterns, mental health and daytime functioning.
- Conditions
- Sleep, Sleep Disorders, Circadian Rhythm, Psychiatric Disorder, Sleepiness, Daytime
- Trial name
- NCT06657482
- Testing
- Delayed school start time
- Where
- Norway
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Sleep Disorder
Safety and Efficacy of Ramelteon in Healthy Subjects
The purpose of this study is to determine the phase-advance in circadian rhythms in healthy adults subjects taking ramelteon, once daily (QD).
- Trial name
- NCT00671190
- Testing
- Ramelteon
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Takeda
Sick Leave, Insomnia
Health Promoting Work Schedules: The Effect of Abolishing Quick Returns
Introduction In shift work, quick returns refer to transitions between two shifts with less than 11 hours available rest time. Twenty-three per cent of employees in European countries reported having quick returns.
- Conditions
- Sick Leave, Insomnia, Shift-Work Sleep Disorder, Psychological Distress
- Trial name
- HeWoS (NCT04693182)
- Testing
- Shift schedule without quick returns
- Where
- Norway
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Atrium; Fibrillation, Arrhythmia Atrial
Enhanced Diagnostics for Early Detection of Atrial Fibrillation - Prospective Validation
Prospective, blinded, multicenter international trial to test the Preventicus Heartbeats App in a prospective cohort.
- Trial name
- DETECTAF-pro (NCT02949180)
- Testing
- Five minutes puls wave recording
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 672 people
- Sponsor
- University Hospital, Basel, Switzerland
Sleep Disorders, Circadian Rhythm, Insomnia
Actigraphic Analysis of Treatment Response
The study examines and illustrates the utility of utilizing actigraphic measurements to assess treatment response.
- Conditions
- Sleep Disorders, Circadian Rhythm, Insomnia, Psychomotor Agitation
- Trial name
- NCT00723580
- Testing
- risperidone
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Child Psychopharmacology Institute
Obesity, Shift-work Disorder
Night Shift Work and Biomarkers of Obesity Risk in Hospital and Industry Workers
Shift work is a well-known risk factor for the development of overweight and obesity, which may lead to downstream effects such as increased risk of cardiometabolic diseases and cancer.
- Conditions
- Obesity, Shift-work Disorder, Circadian Rhythm Disorders
- Trial name
- Shift2Health (NCT06288568)
- Testing
- No intervention
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Healthy
Circadian System Heritability Assessed in Free Living Conditions
The purpose of this investigation is to assess the role of the genetic and environmental factor on circadian system, in free living conditions by the use of a female twin population.
- Trial name
- MTR (NCT03059576)
- Testing
- Chronobiological status of the subjects
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Universidad de Murcia
Cardiac Pacemaker, Cardiac Rhythm Disorder
AVEIR Remote Care System Non-Significant Risk Study
The goal of the study is to understand the performance of the AVEIR Remote Care System in an initial patient cohort which will inform the ability to offer a remote follow-up solution to all patients implanted with Aveir LP…
- Conditions
- Cardiac Pacemaker, Cardiac Rhythm Disorder, Bradycardia
- Trial name
- NCT06542133
- Testing
- AVEIR remote care system
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Atopic Dermatitis, Pruritus
Treatment of Chronic Itch in Atopic Dermatitis With Topical Naltrexone
To study the etiology and the epigenetic pathways leading to and regulating chronic itch. Similarly, to examine the mechanisms underlying skin changes, including epigenetic alterations while also testing the efficacy of…
- Conditions
- Atopic Dermatitis, Pruritus, Dermatitis
- Trial name
- NCT04154033
- Testing
- Naltrexone
- Where
- United States
- Sponsor
- University of Minnesota
Sleep Disorders, Circadian Rhythm
Effects of Vitamin B12 on the Body's Internal Clock
Circadian rhythms are 24-hour cycles that influence natural functions in the body such as heart rate, blood pressure, and body temperature. Circadian rhythms provide the body with an internal clock and affect sleep patterns.
- Trial name
- NCT00120484
- Testing
- Vitamin B12
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Rolandic Epilepsy
Music Perception in SeLECTs
Self-limited epilepsy with centrotemporal spikes (SeLECTS) is the most frequent epilepsy syndrome in children between the ages of 4 and 13 years.
- Trial name
- EpiMUS (NCT06545708)
- Testing
- Patients
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Multiple Sclerosis
Effects of Fingolimod on Heart Rhythm and Heart Rate Variability in Patients With Multiple Sclerosis
The current study sought to prolong the observational interval after initiating medication with fingolimod and to measure the long-term effects of fingolimod on HR and HRV as an indicator of autonomic nervous system function in…
- Trial name
- FINGORHYMS (NCT03216915)
- Testing
- Gilenya®; Novartis Pharmaceuticals Corporation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Diabetes Mellitus, Type 2, Circadian Rhythm
Circadian Rhythm and Metabolic Effects of Exercise
Physical exercise is efficacious in controlling blood glucose levels in individuals with Type 2 diabetes. An individual's exercise capacity and ability to utilize glucose as an energy source oscillates throughout the day.
- Conditions
- Diabetes Mellitus, Type 2, Circadian Rhythm, Glycemic Control
- Trial name
- HITMet (NCT05115682)
- Testing
- High-intensity Intermittent Exercise
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Chronic Kidney Disease
Circadian Rhythm of Erythropoietin And Melatonin in Renal Disease
Rationale: Investigation of the circadian rhythm of erythropoietin and melatonin in patients with various degrees of renal insufficiency Objectives: Primary objective: Is there a circadian rhythm of epo and melatonin in patients…
- Trial name
- CREAM 1 (NCT00698360)
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Meander Medical Center
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