Clinical trials: Rhythm
Sleep, Circadian Rhythm
Morning Bright Light Therapy and Daytime Functioning in University Students
This study tests whether a week of morning bright light therapy changes how well healthy young adults sleep and how alert, positive, and mentally sharp they feel during the day.
- Conditions
- Sleep, Circadian Rhythm, Daytime Sleepiness, Mood
- Trial name
- BLIGHT (NCT07685262)
- Testing
- Bright light therapy (10,000 lux light box)
- Where
- Hong Kong
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hypoxia in Rectal Cancer
RHYTHM-I: Investigating Hypoxia in Rectal Tumours
A low level of oxygen in cancer cells makes them less likely to respond to chemotherapy and radiotherapy treatments. There is interest in using new drugs that improve the level of oxygen in tumours.
- Trial name
- RHYTHM-I (NCT02157246)
- Testing
- Pimonidazole, F-MISO PET, pCT
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Oxford
Seasonal Affective Disorder, Mood Disorders
Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD)
We are offering non-pharmacologic therapy for alleviation of symptoms associated with depressed mood that recurs annually in fall or winter.
- Conditions
- Seasonal Affective Disorder, Mood Disorders, Depression
- Trial name
- NCT00006517
- Testing
- bright light box, dawn simulator, high-output negative ion generator
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- New York State Psychiatric Institute
Eating Disorder, Binge Eating
A Pilot Test of Mood and Circadian Rhythm Mechanisms Driving Binge Eating
Mood and circadian rhythm disruptions are associated with binge eating (BE). BE is a discrete, episodic behavior characterized by 1) eating an objectively large amount of food and 2) experiencing a subjective sense of loss of…
- Conditions
- Eating Disorder, Binge Eating, Circadian Dysregulation
- Trial name
- NCT03680989
- Testing
- Bright Light Exposure, Natural Light Exposure
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Wyoming
Electrical Alternation of Heart, Blood Pressure
Impact of Energy Drink Brands on Heart Rhythm
To assess the cardiac effects of energy drink brands in healthy volunteers
- Trial name
- NCT03196908
- Testing
- Energy Drink Brand 1, Energy Drink Brand 2
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of the Pacific
Pulmonary Arterial Hypertension
Pulmonary Hypertension: Intensification and Personalisation of Combination Rx
The goal of this clinical trial is to evaluate the capacity of implantable/remote technology for early evaluation of drug therapies in patients with pulmonary arterial hypertension (PAH).
- Trial name
- PHoenix (NCT05825417)
- Testing
- Selexipag, Riociguat, CardioMEMS pulmonary artery pressure monitor
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Mild Cognitive Impairment, Alzheimer Disease
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
The goal of this clinical trial is to learn if restricting the time of eating to allow for prolonged fasting at night may reduce sleep disturbances, cognitive decay, and pathology in patients diagnosed with Mild Cognitive…
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Alzheimer's Disease
- Trial name
- TREAD (NCT06548191)
- Testing
- Time-restricted eating
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity, Cardiovascular Diseases
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death.
- Conditions
- Obesity, Cardiovascular Diseases, Hypertension, Nocturnal Blood Pressure
- Trial name
- PRECISION-BP (NCT04971720)
- Testing
- Sacubitril-Valsartan 49 Mg-51 Mg Oral Tablet, Valsartan 80 mg Oral Tablet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cerebral Palsy, Child
EEG in Children With Unilateral Cerebral Injury During Action and Action Observation(AOE)
To study the reactivity of the mu rhythm during action and action-observation by EEG in children with unilateral cerebral injury.
- Trial name
- AOE (NCT02597374)
- Testing
- EEG
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers
ECG, Ventricular Arrhythmias
Hybrid Score to Predict OTVA-SOO in Patients with Wide Basal QRS
Outflow tract ventricular arrhythmia (OTVA) is the most common type of ventricular arrhythmia, and catheter ablation (CA) is the primary treatment option for patients experiencing symptoms.
- Conditions
- ECG, Ventricular Arrhythmias, Catheter Ablation
- Trial name
- NCT06602635
- Testing
- ECG and clinical score
- Where
- 6 sites in Belgium, Italy and 1 more
- Volunteers
- 100 people
- Sponsor
- Centro Medico Teknon
Cardiac Implantable Electronic Devices
National Tunisian Registry of Cardiac Implantable Electronic Devices
The National Tunisian Registry of Cardiac Implantable Electronic Devices is an observational, prospective and multicenter study aiming to assess the epidemiological, clinical and therapeutic profile of cardiac implantable…
- Trial name
- NATURE-CIED (NCT05361759)
- Testing
- Cardiac Implantable Electronic Devices
- Where
- Tunisia
- Volunteers
- 1,518 people
- Sponsor
- Dacima Consulting
Healthy Women
Timing of Food Intake Impacts Daily Rhythms of Human Saliva Microbiota
The purpose of this investigation is to test the hypothesis that in humans, eating late may induce changes in saliva microbiota daily rhythms towards a more obesogenic and a less responsiveness to dietary treatments profile.
- Trial name
- ONTIME-MIC (NCT03147703)
- Testing
- Food Timing
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Atrial Fibrillation, Atrial Flutter
Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Male Subjects
The purpose of this study is to demonstrate the ability of tedisamil to convert atrial fibrillation or flutter into normal sinus rhythm (NSR) in male patients.
- Trial name
- NCT00126061
- Testing
- Tedisamil sesquifumarate
- Where
- 26 sites in United States, Czechia and 3 more
- Sponsor
- Solvay Pharmaceuticals
Schizophrenia
Study of add-on Ramelteon Therapy on Sleep and Circadian Rhythm Disruption in Patients With Schizophrenia
The proposed study has been planned to evaluate the effect of add-on ramelteon on sleep pattern/quality and circadian rhythm disruption in patients with schizophrenia.
- Trial name
- NCT03075657
- Testing
- Risperidone, Risperidone and Ramelteon, Haloperidol
- Where
- India
- Volunteers
- 120 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Breast Feeding, Exclusive, Hospitalization
The Effect of Chronobiologic Feeding Model on Circadian Rhythm in Newborns
This study was planned to evaluate the effect of "feeding model with chronobiologic approach" on circadian rhythm, growth and physiologic parameters of newborns.
- Conditions
- Breast Feeding, Exclusive, Hospitalization, Feeding Patterns
- Trial name
- NCT05923437
- Testing
- Feeding model group with a chronobiological approach
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Healthy Night Shift Workers
Light and Exercise in Night-shift Workers
EuRhythDia is a multicenter, controlled and randomized study. The aim of the study is to investigate the effects of 12 weeks of randomized timed light therapy or timed physical exercise as a chronotherapeutic lifestyle…
- Trial name
- NCT01767181
- Testing
- Intensive light therapy, Exercise
- Where
- Germany
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Circadian Rhythm Disorders, Intestinal Flora
An Observational Clinical Study on the Intestinal Flora in Circadian Rhythm Disorder and Healthy Controls
An observational clinical study on the changes of intestinal flora between people with circadian rhythm disorders and healthy controls was conducted to explore the relationship between circadian rhythm disorders and human…
- Trial name
- NCT05694481
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Third Military Medical University
Pregnancy, Prolonged
Effects of Sleep, Fatigue, and Timing of Post-dates Inductions Among Nulliparas
This randomized clinical trial will examine if there are any differences between post-dates inductions (inductions after 40 weeks of pregnancy) begun in the morning compared to the evening for first-time mothers.
- Trial name
- NCT01542151
- Testing
- Time of labor induction
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, San Francisco
Sleep Disorder Circadian Rhythm, Delayed Sleep Phase Type
SleepHelsinki! CIRCADIAN SLEEP REGULATION IN ADOLESCENCE
Adolescence associates with alterations in sleep-wake organization, such as later circadian phase preference. Simultaneously external pressures, such as evening-driven social activities increase.
- Trial name
- SleepHel (NCT02964598)
- Testing
- Gamified intervention, Sleep coaching, Bright light
- Where
- Finland
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Atrial Fibrillation
Measurement of Left and Right Atria From CT Scans of Cardiac Rhythm Disorder Cases
The purpose of this study is to gather information about the size and shape of patients' hearts in order to design a device.
- Trial name
- NCT01165593
- Testing
- There is no intervention that is a part of this study.
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- Kardium Inc.
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