Clinical trials: Rhythm
Working Memory
Modulation of Brain Oscillations Underlying Working Memory
This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie working memory.
- Trial name
- NCT05923606
- Testing
- Active tACS
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Electromagnetic Interference
Safety of Screening Procedures With Hand-held Metal Detectors Among Patients With Implanted Cardiac Rhythm Devices
Patients with implanted pacemaker (PM) or cardioverter-defibrillator (ICD) systems are restrained in daily life by possible electromagnetic interference (EMI).
- Trial name
- NCT01369706
- Testing
- Hand-held metal detector
- Where
- 2 sites in Germany, Greece
- Volunteers
- 388 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Circadian Rhythms, Time Perception
The Effect of a Continuous 1-Hour Time Delay on Circadian Rhythms
The purpose of this study is to investigate whether the experience of a daily time delay can affect our internal circadian rhythm.
- Conditions
- Circadian Rhythms, Time Perception, Sleep
- Trial name
- NCT07317349
- Testing
- Fixed daily routine, Daily time delay
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Atrial Fibrillation
Resync-AF (Rate vs Rhythm Control in AF Patients With CRT-D)
This study is being done to find out if controlling rate or controlling rhythm is better for heart failure patients who also have AF.
- Trial name
- NCT01233648
- Testing
- rate control via CRT-D and AVN ablation, rhythm control via pharmacologic, electrical or ablative therapies
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Pittsburgh
Disorders of Consciousness
The Core Body Temperature Rhythms: Distinguishing MCS From UWS
In this study, the core body temperature of 7 disorders of consciousness ( DOC ) patients were measured every 2 hour for 168 h .
- Trial name
- NCT02930213
- Volunteers
- 7 people
- Sponsor
- Jing Wang
Cardiac Arrhythmias
Bad Berka Heart Rhythm Registry of Patients With or at Risk of Arrhythmias Treated at Heart Center Bad Berka
The Bad Berka Heart Rhythm Registry (2B2R) is a prospective, single-center observational cohort designed to systematically collect and analyze data of patients undergoing cardiac arrhythmia therapy as well as implantation of…
- Trial name
- 2B2R (NCT07020910)
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Zentralklinik Bad Berka
Surgery, Cardiovascular Diseases
Circadian Rhythm Disruption in the Hospital Intensive Care Environment
Abrupt changes to one's lifestyle disrupt biorhythms. Acute effects are well known from jet lag where transmeridian travel leads to insomnia, fatigue, irritability, gastrointestinal symptoms and other complaints.
- Trial name
- NCT05828680
- Testing
- Observation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania
Circadian Timing - Exercise
Timed Exercise Study
The purpose of this study was to investigate the effect of timed exercise on human circadian rhythms. Subjects were randomized to 5 days of morning or evening treadmill exercise.
- Trial name
- NCT04097886
- Testing
- Morning Exercise, Evening Exercise
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Julie Pendergast
Parkinson's Disease
Circadian Rhythms and Sleep-Wake Cycles in Parkinson's Disease
Disruption of sleep and alertness is one of the most disabling non-motor symptoms of Parkinson's disease (PD). Mechanisms leading to impaired sleep and alertness in PD are not well understood, and treatment options remain…
- Trial name
- NCT01742182
- Testing
- Light exposure
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Carpal Tunnel Syndrome
Effectiveness of Matrix Rhythm Therapy on Carpal Tunnel Syndrome
The purpose of this study is to investigate the effects of matrix rhythm therapy, applied in addition to conventional treatment, on symptom severity, function, grip and pinch strength, and quality of life in patients with carpal…
- Trial name
- NCT07660913
- Testing
- Matrix Rhythm Therapy, Conservative Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Izmir Bakircay University
Postpartum Depression (PPD)
Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression
The proposed study is an open-label trial of Re-Timer® wearable morning bright light therapy for postpartum depression. The study is focused on evaluating the feasibility, acceptability, and implementation context of morning…
- Trial name
- NCT07766161
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Melanoma (Skin Cancer), NSCLC (Non-small Cell Lung Cancer)
Bright Light Therapy in Patients With Melanoma or Non-small Cell Lung Cancer (NSCLC) Who Are Receiving First-Line Immune Checkpoint Blockade
This study is being done to test whether bright light therapy can be used to synchronize patients' circadian rhythms and allow ICB (immune-checkpoint blockade) therapy to be administered at a time in the circadian rhythm that…
- Trial name
- IIT BLT (NCT07661966)
- Testing
- Bright Light Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Weill Medical College of Cornell University
Type 2 Diabetes
Restricted Eating Time in the Treatment of Type 2 Diabetes
The overall aim of the present study is to investigate the effectiveness of implementing a 1-year time-restricted eating (TRE)-based intervention on glycaemic control, body weight and composition, cardiometabolic risk factors…
- Trial name
- RESET2 (NCT06152588)
- Testing
- Time restricted eating
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Steno Diabetes Center Copenhagen
Lightning Strategies on Health, Circadian Rhythms Photoentrainment
Population Based Lighting Study on Older Adults
The ENLIGHTENme project aims at collecting evidence about the impact of outdoor and indoor lighting on human health and wellbeing through the development and testing of innovative solutions and policies that will also counteract…
- Conditions
- Lightning Strategies on Health, Circadian Rhythms Photoentrainment, Photoentrainment and Sleep, DLMO
- Trial name
- ENLIGHTENme (NCT05676086)
- Testing
- indoor light intervention, no indoor light
- Where
- Italy
- Volunteers
- 191 people
- Sponsor
- Azienda Usl di Bologna
Alzheimer's Disease, Mild Cognitive Impairment
A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1
The purpose of this research study is to investigate the relationship between reminder messages sent via text and compliance with a daily morning light intervention designed to advance the circadian clock.
- Trial name
- NCT06356337
- Testing
- Light goggles, Daily reminder test message
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obstructive Sleep Apnea (OSA), Exercise Snacks
Exercise Interventions in Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome (OSA) is a condition characterized by repeated pauses or reductions in breathing during sleep, which can negatively affect sleep quality, daytime functioning, and physical capacity.
- Conditions
- Obstructive Sleep Apnea (OSA), Exercise Snacks, Physical Activity, Circadian Rhythm
- Trial name
- NCT07634029
- Testing
- Aerobic Exercise Training, Exercise Snacking
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Istanbul University - Cerrahpasa
Dementia, Alzheimer Disease
The Music, Sleep and Dementia Study
The specific aims of this studyare to examine the 1) feasibility; 2) acceptability; and 3) preliminary efficacy of a tailored music intervention in home-dwelling older adults with dementia suffering from sleep disruption.
- Conditions
- Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder
- Trial name
- NCT04157244
- Testing
- Tailored music listening intervention
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Posttraumatic Stress Disorder, Depression
A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)
The purpose of this study is to test the effectiveness of group psychotherapy designed specifically for male veterans and active-duty personnel with Post-traumatic Stress Disorder (PTSD), Major Depressive Disorder (MDD) and with…
- Conditions
- Posttraumatic Stress Disorder, Depression, Insomnia Disorder
- Trial name
- NCT00984698
- Testing
- Cognitive Behavioral Social Rhythm Group Therapy, Present Centered Group Therapy
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- University of Arizona
Shift-Work Sleep Disorder
Sleep Enhancement Training Study for Experienced Shiftworkers
The purpose of this study is to determine if a modified version of the Sleep Enhancement Fatigue Reduction Training (SEFRT) system can improve sleep and health-related symptoms and quality of life in experienced shift-working…
- Trial name
- SETS-exp (NCT00786357)
- Testing
- NIOSH shiftwork booklet, Sleep Enhancement Training System
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Heart Failure, Recent Onset Atrial Fibrillation
The Comparison With Clinical Impacts on Functional Capacity and Symptom Improvement According to the Rhythm Control in Patients With Heart Failure and Recent Onset Atrial Fibrillation
Prospective randomized (rhythm control or rate control in heart failure patients with new onset atrial fibrillation) Objective of study 1.
- Trial name
- NCT02321085
- Testing
- Sinus Rhythm control, Pulse Rate control
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
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