Clinical trials: Rhythm
Atrial Fibrillation, Atrial Flutter
Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Male Subjects
The purpose of this study is to demonstrate the ability of tedisamil to convert atrial fibrillation or flutter into normal sinus rhythm (NSR) in male patients.
- Trial name
- NCT00126061
- Testing
- Tedisamil sesquifumarate
- Where
- 26 sites in United States, Czechia and 3 more
- Sponsor
- Solvay Pharmaceuticals
Circadian Timing - Exercise
Timed Exercise Study
The purpose of this study was to investigate the effect of timed exercise on human circadian rhythms. Subjects were randomized to 5 days of morning or evening treadmill exercise.
- Trial name
- NCT04097886
- Testing
- Morning Exercise, Evening Exercise
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Julie Pendergast
Bipolar Disorder
Study of the Genetic and Environmental Factors of Vulnerability in Bipolar Disorders
Bipolar disorder is a complex, multifactorial disorder with the intervention of genetic vulnerability factors. To help the identification of these genetic factors and to improve genotype-phenotype correlation, the identification…
- Trial name
- GAN (NCT02627404)
- Testing
- Blood sample, actometer
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Metastatic Colorectal Cancer
"Cancersensor": Circadian Rhythms
Observational, non randomized study aimed at measuring the circadian rhythms in the urinary concentrations of physiological modified nucleosides in 30 patients with metastatic colorectal cancer and in 30 age and sex-matched…
- Trial name
- NCT01693835
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Narcolepsy, Obstructive Sleep Apnea
The Nuvigil and Provigil Pregnancy Registry
The primary objective of the Nuvigil/Provigil Pregnancy Registry is to characterize the pregnancy and fetal outcomes associated with Nuvigil and Provigil exposure during pregnancy.
- Conditions
- Narcolepsy, Obstructive Sleep Apnea, Shift Work Sleep Disorder
- Trial name
- NCT01792583
- Testing
- Modafinil/armodafinil
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Cephalon, Inc.
Parkinson Disease, Sleep Disorder
Light Therapy in Parkinson's Disease
The aim of this randomized controlled trial (RCT) is to clarify the effect of bright light therapy on motor symptoms and sleep disorders in patients with Parkinson's disease.
- Conditions
- Parkinson Disease, Sleep Disorder, Circadian Rhythm Disorders
- Trial name
- NCT06129942
- Testing
- Bright light box, Dim Light box
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Patients With Symptoms of Cardiac Arrhythmia at Risk for Atrial Fibrillation
THE GIRAFFE Study: Genomic Risk Markers for Atrial Fibrillation Following Extended Cardiac Rhythm Monitoring
Our primary hypothesis is that a risk score comprised of approximately 10 single nucleotide polymorphisms (SNPs) that are associated with atrial fibrillation at the Genome Wide Association Study (GWAS) level is associated with…
- Trial name
- GIRAFFE (NCT01970969)
- Where
- United States
- Volunteers
- 928 people
- Sponsor
- Scripps Translational Science Institute
Sleep Disorders, Circadian Rhythm
Nursing Activity and Quality of Hospitalized Patients' Sleep
This study is to determine the impact of night shift nurse's activity on patients' sleeping patterns in medical services including individual, clinical and environmental factors.
- Trial name
- SOMACTIV (NCT03370354)
- Testing
- Observational
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Post-COVID-19 Syndrome
Physical Functions and Lifestyle Behaviours in Post-COVID-19 Syndrome Based on Circadian Rhythms
Post-COVID-19 syndrome is associated with persistent symptoms such as fatigue, reduced physical activity, and impaired respiratory function.
- Trial name
- NCT07545499
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Chronic Insomnia, Circadian Rhythm
Treatment of Chronic Insomnia According to Yin Yang Theory and Its Correlation With Circadian Rhythm
The purpose of this study is to assess the safety and efficacy of Traditional Chinese medicine (TCM) according to Yin Yang theory for treatment of chronic insomnia .
- Conditions
- Chronic Insomnia, Circadian Rhythm, Traditional Chinese Medicine
- Trial name
- NCT05452577
- Testing
- Suanzaoren Decoction and Huanglian Wendan Decoction, Estazolam 1Mg Tab
- Where
- China
- Volunteers
- 187 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Diet, High-Fat, Circadian Rhythm
Food and Circadian Timing
The goals of this study are to uncover the influence of diet on the human circadian timing system. The protocol is a 46-day (28 outpatient days, 18 inpatient days over two 9 day visits) randomized cross-over study designed to…
- Trial name
- FACT (NCT04743271)
- Testing
- High-Fat Diet, Low-Fat Diet
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Breast Feeding, Exclusive, Hospitalization
The Effect of Chronobiologic Feeding Model on Circadian Rhythm in Newborns
This study was planned to evaluate the effect of "feeding model with chronobiologic approach" on circadian rhythm, growth and physiologic parameters of newborns.
- Conditions
- Breast Feeding, Exclusive, Hospitalization, Feeding Patterns
- Trial name
- NCT05923437
- Testing
- Feeding model group with a chronobiological approach
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Atrial Fibrillation
Amiodarone Compared to Dronedarone , Post Cardioversion Maintenance of Sinus Rhythm
Persistent Atrial Fibrillation (AF) is a common and distressing cardiac arrhythmia and accounts for 1% of the healthcare budget in the UK and it's prevalence is rising.
- Trial name
- ACDC (NCT01266681)
- Testing
- amiodarone, Dronedarone
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- East Sussex Healthcare NHS Trust
Aphasia, Apraxia of Speech
Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia
Speaking in unison with another person is included as a part of many treatment approaches for aphasia. It is not well understood why and how this technique works.
- Trial name
- NCT05248295
- Testing
- Unison speech (vs. solo), Metrical timing (vs. conversational)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Skipping Breakfast, Circadian Rhythms
Effect of Skipping Breakfast on Metabolic Function
The purpose of this study is to test the hypothesis that the disruption of the "normal" (three meals a day) eating pattern and prolonged overnight fasting caused by skipping breakfast: i) alters the expression of specific clock…
- Trial name
- NCT02093572
- Testing
- 3 standard meals/day, 2 meals/day (omit breakfast)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Atrial Fibrillation
This Study Observes the Usage of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) in Elderly Patients With a Heart Rhythm Disorder in Spain
This is an observational, multicenter and cross-sectional study in Non-valvular atrial fibrillation (NVAF) elderly patients currently on Non-vitamin K antagonist oral anticoagulant (NOAC) treatment for their stroke prevention.
- Trial name
- NCT03993119
- Testing
- Non-vitamin K antagonist oral anticoagulant
- Where
- 45 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Boehringer Ingelheim
Alteration of Cognitive Function, Ageing
Health Behaviors and Time-of-Day: Older Adult Cognitive Function
This is a single-center, observational study design. Enrolled participants will be typically, healthy older adults. Participants will complete daily computerized measures, in addition to continuously wearing an Actiwatch device.
- Trial name
- OA-TIME (NCT02300272)
- Testing
- Polysomnograph, Actiwatch
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Florida
Scapular Dyskinesis, Handball Players
The Effectiveness of an Exercise Program on Scapulohumeral Rhythm, Range of Motion, and Stability in Young Female Handball Players
This record describes a planned randomized parallel-group trial of a modified Watson-based shoulder exercise program in female handball players.
- Conditions
- Scapular Dyskinesis, Handball Players, Female Athlete
- Trial name
- NCT06875596
- Testing
- Modified Watson-based scapular exercise program, Active Comparator: Standard upper-limb exercise program
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Chronic Insomnia, Cognitive Behavioral Therapy
Cognitive Behavioral Therapy for Insomnia Among Different Types of Shift Workers
The aim of the study is to compare the implementation and effectiveness of group and self-help based cognitive behavioral treatment for insomnia (CBT-I) delivered by occupational health services (OHS) in a randomized and…
- Conditions
- Chronic Insomnia, Cognitive Behavioral Therapy, Sleep Disorders, Circadian Rhythm, Sleep Disorders, Shift-Work
- Trial name
- CBT-INSOMNIA (NCT02523079)
- Testing
- Cognitive Behavioral Group Therapy for Insomnia, Cognitive Behavioral Self-help Therapy for Insomnia, Sleep Hygiene Guidance
- Where
- 5 sites in Finland
- Volunteers
- 83 people
- Sponsor
- Finnish Institute of Occupational Health
Atrioventricular Reentrant Tachycardia
Non-invasive Left-sided Cervical Vagus Nerve Stimulation for Atrioventricular Reentrant Tachycardia
The goal of this Interventional clinical trials in atrioventricular reentrant tachycardia patients. The main question it aims to answer whether non-invasive vagus nerve stimulation could be effective in restoring rhythm.
- Trial name
- NCT06219343
- Testing
- Non-invasive vagus nerve stimulation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Jingye Tai
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