Clinical trials: Rhythm
Cerebral Palsy (CP), Unilateral Cerebral Palsy
Neural Correlates of Goal-directed Action Observation and Execution in Children With Unilateral Cerebral Palsy
Cerebral palsy (CP) is the most common childhood-onset motor disorder, with Unilateral Cerebral Palsy (UCP)- motor impairment predominantly impacting one side of the body-representing the most frequent form of CP.
- Conditions
- Cerebral Palsy (CP), Unilateral Cerebral Palsy, EEG, Action Observation
- Trial name
- EEG_AINCP (NCT07369167)
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Breast Cancer, Prostate Cancer
Methylselenocysteine Effects on Circadian Rhythm
The primary objective of this study is to determine if vitamin supplementation with a naturally occurring dietary amino acid called organic selenium (i.e., methylselenocysteine) can restore disruption of circadian rhythm in shift…
- Trial name
- NCT01611038
- Testing
- Methylselenocysteine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Diabetic Retinopathy, Melatonin
Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm
This study evaluates the effect of melatonin 4 mg on circadian rhythm and visual function of patients with diabetes mellitus. Half of the patients will receive melatonin (arm-1) and the other half will receive placebo (arm-2)…
- Conditions
- Diabetic Retinopathy, Melatonin, Circadian Dysrhythmia, Circadian Rhythm Sleep Disorder, Unspecified Type
- Trial name
- NCT03478306
- Testing
- Melatonin 4 mg Tablet
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Atrial Fibrillation, Heart Failure
Randomized Ablation-based AF Rhythm-control Versus Rate-control in Patients With HF and High-burden AF Extend
This is an extended follow up study of the original RAFT-AF Study. The RAFT-AF study was a multi-centre randomized controlled trial with a prospective randomized open blinded endpoint trial (PROBE) design.
- Trial name
- RAFT-AF Extend (NCT05118893)
- Where
- 11 sites in Canada
- Volunteers
- 324 people
- Sponsor
- Anthony Tang
Heart Failure (NYHA Class III and Ambulatory IV)
Continued Access Clinical Trial of the SonRtip Lead and Automatic AV-VV Optimization Algorithm in the PARADYM RF SonR CRT-D
The objective of the Continued Access study is to gather confirmatory evidence on the safety of the SonRtip lead and performance of the automatic atrioventricular (AV) delay and interventricular (VV) delay optimization algorithm…
- Trial name
- RESPOND-CAS (NCT02374801)
- Testing
- SonR automatic optimization feature turned ON ("AV+VV").
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- MicroPort CRM
Healthy
the Effects of Different Dietary Phosphorus Intake on the Circadian Pattern of Serum Phosphate in Normal Subjects
The purpose of this study is to investigate the effects of normal diet and low-phosphate diet on the level and the circadian pattern of serum phosphate concentration in normal subjects and to explore the underlying mechanisms.
- Trial name
- NCT02636153
- Testing
- normal diet, restricted phosphate diet
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Appropriate and Inappropriate Shock Therapy With ICD, Arrhythmias Detection
Arrhythmias Detection in a Real World Population
The study is a prospective multicenter registry. Consecutive patients with indications of implant / replacement or upgrade of implantable cardioverter defibrillator (ICD) will be enrolled.
- Trial name
- RHYTHM DETECT (NCT02275637)
- Testing
- implantable cardioverter defibrillator
- Where
- 12 sites in Italy
- Volunteers
- 10,000 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Learning Disorder, Specific, Learning Disabilities
Rhythm Training of a Serious Game on the Reading Skills of Children w/ a Specific Learning Disorder Impacting Reading
Mila-Learn-01 is a double-blind clinical study (meaning that neither the patient nor the doctor or his/her team will know which game the child has), which enables us to see the effect of a serious game on the child's reading…
- Conditions
- Learning Disorder, Specific, Learning Disabilities, Dyslexia, Specific Learning Disorder, With Impairment in Reading
- Trial name
- NCT05154721
- Testing
- experimental Group - Mila-Learn
- Where
- 3 sites in France
- Volunteers
- 151 people
- Sponsor
- Poppins
Delirium, Postoperative, Cognitive Decline
Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium
The goal of this prospective cohort study is to assess potential differences in sleep biomarkers in older adult patients undergoing major orthopedic surgery. The main questions it aims to answer are: 1.
- Conditions
- Delirium, Postoperative, Cognitive Decline, Dementia
- Trial name
- SLEEP-POD (NCT06052397)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Sleep Disorders, Circadian Rhythm
The Impact of Night Float on Anesthesiology Resident Sleep Patterns
Residency training requires hospital presence twenty-four hours a day. At times this necessitates working extended shifts, including night shifts, resulting in altered sleep patterns and sleep deprivation.
- Trial name
- NCT03325244
- Testing
- EEG monitor, FitBit
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Cardiomyopathies
Multislice Spiral Computed Tomography and Cardiomyopathy
Conventional coronary angiography is the recommended procedure in detection of coronary stenosis in patients with idiopathic cardiomyopathy.
- Trial name
- CMD-scanner (NCT00305916)
- Testing
- Multislice spiral computed tomography coronary angiography, conventional coronary angiography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Rennes University Hospital
Opioid Use Disorder, Sleep
The Effect of Light Intervention on Recovery in Individuals With Opioid Use Disorder (OUD)
Opioid use disorder (OUD) is a chronic relapsing disorder and is well-known for its high-risk rate of overdoses and death. In OUD, sleep and circadian disruptions are highly prevalent, interfere with opioid maintenance treatment…
- Conditions
- Opioid Use Disorder, Sleep, Circadian Rhythms, fMRI Research
- Trial name
- NCT06832007
- Testing
- AYO light glasses (experimental), AYO light glasses (comparator)
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Post Stroke Depression, Post Stroke Fatigue
The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission for Rehabilitation.
Background: Light is the most important regulator of circadian rhythm. Naturalistic light, which contains the spectrum of sunlight throughout the day, has been shown to have a positive impact on mental states such as depression…
- Conditions
- Post Stroke Depression, Post Stroke Fatigue, Circadian Dysregulation, Stroke
- Trial name
- NCT06922409
- Testing
- Naturalistic Light Intervention
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arrhythmia
Study Evaluating GAP-486 on Heart Rhythm in Patients With Coronary Artery Disease
The purpose of this study is to learn the effects of a test drug on heart rhythms, which may become life-threatening if left untreated, and to provide data to see if the drug is well tolerated and safe.
- Trial name
- NCT00137332
- Testing
- GAP-486 (ZP-123), 0.9% Sodium Chloride, USP
- Where
- 33 sites in United States, Canada
- Volunteers
- 90 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Metabolic Syndrome, Postmenopausal Symptoms
Circadian Rhythms in Postmenopausal Women
This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms…
- Trial name
- NCT04893226
- Testing
- Time-Restricted Feeding (TRF)
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Julie Pendergast
Insomnia Chronic, Sleep Disorder
Light Therapy for Chronic Insomnia in General Practice
Sleep disorders, especially insomnia Attention deficits (or disorders), daytime somnolence and drug dependence The goal is to evaluate whether light therapy could be used as an efficient alternative treatment with direct…
- Conditions
- Insomnia Chronic, Sleep Disorder, Circadian Rhythm Disorders
- Trial name
- Insolux (NCT04612192)
- Testing
- Active luminette
- Where
- 3 sites in France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiac Rhythm Disorder
EP Device Registry
This study will provide ongoing, high quality data on the safety, performance, and clinical benefits of Abbott's EP devices in a real-world setting.
- Trial name
- NCT04460209
- Testing
- Standard of Care
- Where
- 26 sites in Austria, Czechia and 8 more
- Volunteers
- 5,003 people
- Sponsor
- Abbott Medical Devices
Post-COVID-19 Syndrome
Physical Functions and Lifestyle Behaviours in Post-COVID-19 Syndrome Based on Circadian Rhythms
Post-COVID-19 syndrome is associated with persistent symptoms such as fatigue, reduced physical activity, and impaired respiratory function.
- Trial name
- NCT07545499
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Sleep Phase Rhythm Disturbance
Noise in the Intensive Care Care Unit and Its Influence on Cortical Arousals and Sleep Phases
This is a prospective observational study in an Italian general-neurologic ICU. Sleep was monitored during the night, using a simplified polysomnography(PSG), for a maximum of five consecutive nights.
- Trial name
- NCT03942393
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università degli Studi di Brescia
Cognitive Performance, Brain Structure
Rhythm Experience and Africana Culture Trial
REACT is a randomized intervention to examine the benefits of African Dance as a method to increase physical activity behaviors in older adults.
- Trial name
- REACT (NCT03771716)
- Testing
- African Dance, African Cultural Immersion
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
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