Clinical trials: Rhythm
Refractory Epilepsy, Arrhythmia
Cardiac Rhythm Abnormalities in Patients With Refractory Epilepsy at High Risk for Sudden Death
People with epilepsy are at a higher risk for sudden unexpected death than the general population. Sudden unexpected death in epilepsy (SUDEP) is a major cause of death in this population, accounting for 10-50% of deaths for…
- Conditions
- Refractory Epilepsy, Arrhythmia, Sudden Death
- Trial name
- NCT00203333
- Testing
- Medtronic REVEAL
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Thomas Jefferson University
Psychosis, Sleep
Melatonin Effects on Sleep and Circadian Rhythm in Youth and Young Adults With At-risk Symptoms
Randomized control trial assessing supplemental melatonin for youth with at-risk or psychotic symptoms.
- Trial name
- NCT03826563
- Testing
- oral melatonin tablets (NatureMade brand)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia
Mitral Stenosis
Effect of Ivabradine on Heart Rate & Effort Tolerance in Mitral Stenosis in Sinus Rhythm
The purpose of this study is to study the effect of Ivabradine vs Atenolol on heart rate and effort tolerance in patients with mild to moderate mitral stenosis and normal sinus rhythm.
- Trial name
- IVA-MS (NCT01022463)
- Testing
- Ivabradine, Atenolol
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Govind Ballabh Pant Hospital
Depression, Postpartum, Anxiety State
From Prevention to Treatment: How Biological Rhythms Can Maintain Perinatal Mental Health
Depression and anxiety are significant public health issues during pregnancy and the postnatal period, particularly affecting those in developing countries.
- Trial name
- NCT06246214
- Testing
- Blue Light Therapy, ControlLT
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Transcutaneous Electric Nerve Stimulation, Heart Rate
TENS Impact Heart Rate Via Vagus Activity
Transcutaneous electric nerve stimulation (TENS) is widely used for the treatment of adhesive capsulitis, nevertheless, its potential impact on heart physiology has not been well established.
- Trial name
- NCT03982472
- Testing
- transcutaneous electric stimulation
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Mitral Stenosis
Role of Ivabradine on Heart Rate and Quality of Life in Patients With Mitral Stenosis in Sinus Rhythm
Mitral stenosis, a condition characterized by narrowing of the mitral valve orifice, remains a significant cause of morbidity and mortality worldwide, particularly in regions where rheumatic fever is endemic.
- Trial name
- NCT06371222
- Testing
- Ivabradine, Beta blocker
- Where
- Bangladesh
- Volunteers
- 42 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Cardiac Arrest
Therapeutic Hypothermia After Cardiac Arrest in Non Shockable Rhythm
Cardiac arrest is at present a major cause of mortality as well as a cause of disability for the surviving victims.In Europe, every year counts as 300,000 cardiac arrests responsible for 250,000 deaths.
- Trial name
- HYPERION (NCT01994772)
- Testing
- Targeted controlled temperature between 32.5 and 33.5°C, Targeted controlled temperature between 36.5 and 37.5°C
- Where
- 26 sites in France, Guadeloupe
- Volunteers
- 584 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Smith-Magenis Syndrome, Autism Spectrum Disorder
Smith Magenis Syndrome and Autism Spectrum Disorders
Autism Spectrum Disorders (ASD) are a neurodevelopmental disorder. Their prevalence is estimated at around 0.4% of the general population worldwide.
- Trial name
- SMS/TSA (NCT05116904)
- Testing
- Assessment
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Dyslexia
Evaluation of Speech Rhythm Training in Dyslexic Readers Aged 7 to 9 Years
Studies of dyslexia have shown altered oscillatory activity in the low gamma band (~25-35 Hz) in the left auditory cortex. Neural oscillations around 30 Hz constitute the basic sampling rate of speech, from which the ability to…
- Trial name
- RnDys (NCT05996497)
- Testing
- behavioral measures, Electrophysiological measures, Training 1
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Institut Pasteur
Delirium in Old Age, Sleep Disturbance
Sleep & Postoperative Delirium in Hispanic/ Latino Patients After Cardiothoracic Surgery
The purpose of this research is to study pre-operative sleep problems and delirium in Hispanic/Latino patients after heart and lung surgery.
- Conditions
- Delirium in Old Age, Sleep Disturbance, Circadian Rhythm Sleep Disorder
- Trial name
- NCT04786899
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Miami
Cholestasis of Pregnancy, Intrahepatic Cholestasis of Pregnancy
Bile Acid Effects in Fetal Arrhythmia Study
Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder of pregnancy that typically presents in late pregnancy with generalised itching.
- Conditions
- Cholestasis of Pregnancy, Intrahepatic Cholestasis of Pregnancy, Obstetric Cholestasis
- Trial name
- BEATS (NCT03519399)
- Testing
- Monica AN24
- Where
- 2 sites in United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Hypertension, Cardiovascular Risk Factor
Sleep and Circadian Mechanisms of Non-dipping Blood Pressure
This study will be the first to distinguish the relative contributions of sleep, circadian and behavioral mechanisms to the non-dipping BP profile in Black adults and will lay the groundwork for optimizing therapies dependent on…
- Trial name
- NCT03558893
- Testing
- Forced Desynchrony
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Heart Failure, Atrial Arrhythmia
Restoring Sinus Rhythm With Cardiac Resynchronization in Patients With Atrial Fibrillation (ReSync AF)
Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes.
- Trial name
- NCT00268294
- Testing
- Cardiac Resynchronization Therapy
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Aging, Postural Balance
Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age
This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control…
- Conditions
- Aging, Postural Balance, Accidental Falls
- Trial name
- NCT07567976
- Testing
- Tai Chi Exercise, Health Education
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhide Liang
COVID-19, Atrial Fibrillation New Onset
Natural History of COVID-19-Related Atrial Fibrillation
The unCOVer-AF prospective, multicenter registry aims at determining the natural history of atrial fibrillation (AF) via continuous cardiac rhythm monitoring in patients with a first arrhythmic episode during COVID-19…
- Trial name
- unCOVer-AF (NCT04830774)
- Testing
- ILR, PMK, ICD
- Where
- 12 sites in United States, Belgium and 1 more
- Volunteers
- 200 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Stroke
Modulation of Brain Rhythms in Stroke
The goal of this research study is to examine communication between brain and muscle in individuals with stroke and determine if applying non-invasive brain stimulation to different parts of the brain improves this communication…
- Trial name
- NCT07121582
- Testing
- Motor Brain Stimulation, Visual Brain Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Brugada Syndrome
UZ Brussel HRMC Registry of Brugada Syndrome
The monocentric UZB registry for Brugada registry is intended to collect all data on patients affected by Brugada syndrome at UZ Brussel hospital (UZB).
- Trial name
- HRMCBrS (NCT05283759)
- Testing
- No intervention because it is a patient registry
- Where
- Belgium
- Volunteers
- 2,000 people
- Sponsor
- Universitair Ziekenhuis Brussel
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Acute Ischemic Stroke, Atrial Fibrillation
Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE
This study will determine whether early, comprehensive, rhythm control therapy prevents adverse cardiovascular outcome in patients with acute ischemic stroke and atrial fibrillation compared to usual care.
- Trial name
- EAST-STROKE (NCT05293080)
- Testing
- Medical or interventional therapy for rhythm control in atrial fibrillation (antiarrhythmic drugs, ablation, electric cardio version), Usual care for atrial fibrillation
- Where
- Germany
- Volunteers
- 1,746 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Carpal Tunnel Syndrome
Effectiveness of Matrix Rhythm Therapy on Carpal Tunnel Syndrome
The purpose of this study is to investigate the effects of matrix rhythm therapy, applied in addition to conventional treatment, on symptom severity, function, grip and pinch strength, and quality of life in patients with carpal…
- Trial name
- NCT07660913
- Testing
- Matrix Rhythm Therapy, Conservative Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Izmir Bakircay University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.