Clinical trials: Rhythm
Hypertrophic Cardiomyopathy, Hypertrophic Obstructive Cardiomyopathy
Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository
The Hearts in Rhythm Organization (HiRO) is a national network of Canadian researchers/clinicians, working towards a better understanding of the rare genetic causes of sudden cardiac death (SCD).
- Conditions
- Hypertrophic Cardiomyopathy, Hypertrophic Obstructive Cardiomyopathy, Familial Hypertrophic Cardiomyopathy, Cardiomyopathies
- Trial name
- HiRO-HCM (NCT05100420)
- Where
- 17 sites in Canada
- Volunteers
- 2,000 people
- Sponsor
- Montreal Heart Institute
Delayed Sleep Phase Syndrome
Lemborexant in Delayed Sleep Phase Syndrome
The purpose of the study is to evaluate whether Lemborexant is more effective than placebo in shortening sleep onset latency in patients with delayed sleep phase syndrome (both type 1 and type 2).
- Trial name
- NCT05463861
- Testing
- Lemborexant
- Where
- 2 sites in United States
- Volunteers
- 86 people
- Sponsor
- Stanford University
Developmental Dyslexia
Rhythmic Reading Training Compared to 'Abilmente' Method
The purpose of the present study is to compare the effectiveness of Rhythmic Reading Training (RRT), a computer-assisted intervention method that combines sublexical reading exercises with rhythm processing, and that of a…
- Trial name
- NCT03199092
- Testing
- RRT+sat, Abilmente
- Where
- 2 sites in Italy
- Volunteers
- 32 people
- Sponsor
- Catholic University of the Sacred Heart
Circadian Rhythm Sleep Disorder, Jet Lag Type
Factors Associated With Infant Circadian Rhythm, Growth, and Temperament
The goal of this observational study is to learn about the role of modifiable factors affecting infant circadian rhythm so that recommendations can be made for better health outcomes for the mother and infant.
- Trial name
- NCT05700136
- Testing
- MOMENT
- Where
- 10 sites in Malaysia
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- UCSI University
Shift Work Type Circadian Rhythm Sleep Disorder
The Influence of Nocturnal Food Intake in Eating Behavior of Night Workers
This study aimed to verify the influence of night work and food intake during the night shift on the eating behavior of fixed night workers the next day.
- Trial name
- NCT03800732
- Testing
- With Meal during night work, Without Meal during night work, Sleep night
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Seasonal Affective Disorder
Effects of Season on Melatonin Secretion in Healthy Men and Women and Patients With Seasonal Affective Disorder
As the seasons change during the course of the year, many animals show major changes in their behavior and physiology. Many of these changes are triggered by changes in the length of time each night that the pineal gland produces…
- Trial name
- NCT00001485
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Cardiac Rhythm Disorders, Urological Disorders
Product Surveillance Registry
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products.
- Conditions
- Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders
- Trial name
- PSR (NCT01524276)
- Where
- 402 sites in United States, Argentina and 39 more
- Volunteers
- 100,000 people
- Sponsor
- Medtronic
ADHD - Attention Deficit Disorder With Hyperactivity, ADHD
Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition
The purpose of this study is to better understand sleep and circadian functioning in children with ADHD using home-based measures, parent report, and a lab based melatonin assessment.
- Trial name
- CIRCA (NCT06971640)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Duke University
Dietary Intervention
Eating to Adjust the Timing System
The goal of this clinical trial is to test the effects of dietary composition on the rhythms of food intake, appetite regulation, and rhythms of energy expenditure.
- Trial name
- EATS (NCT05800990)
- Testing
- dietary intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Stroke, Gait, Hemiplegic
Effect of RAS on Balance and Gait After Stroke
A rhythmic auditory stimulation intervention may be beneficial in order to improve movement parameters after stroke. Reviews argue that more randomized controlled trials with a control group are needed.
- Conditions
- Stroke, Gait, Hemiplegic, Gait Disorders, Neurologic
- Trial name
- NCT03974490
- Testing
- Rhythmic auditory stimulation
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Hospital Sociosanitari Mutuam Girona
Autism, Autism Spectrum Disorder
Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers
The primary goal of this study is to examine rhythm sensitivity as a predictor of response to naturalistic developmental behavioral intervention (NDBIs) in autistic toddlers.
- Trial name
- NCT05880225
- Testing
- Reciprocal Imitation Training, music-enhanced Reciprocal Imitation Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Persistent Atrial Fibrillation
Comparison of Brain Perfusion in Rhythm Control and Rate Control of Persistent Atrial Fibrillation
Atrial fibrillation (AF) is associated with impaired cognitive function (CogF) and/or dementia, but it is unclear whether rhythm control of AF improves CogF or brain perfusion.
- Trial name
- NCT02633774
- Testing
- Propafenone, Apixaban
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm
Evaluating the Effects of Tasimelteon Vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD) and the CRY1Δ11 Variant
This is a double-blind, randomized, two-period crossover study to evaluate the efficacy and safety of a single oral dose of tasimelteon and matching placebo in male and female subjects with DSWPD and the CRY1Δ11 variant.
- Conditions
- Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm, Chronobiology Disorders, Gene Mutations and Other Alterations Nec
- Trial name
- NCT06701396
- Testing
- Tasimelteon
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vanda Pharmaceuticals
Aerobic Exercise, Acute Exercise
Diurnal Variation of Exercise on Metabolic Health
The main objective of this project is to study the diurnal variation of the effect of exercise on glycemic metabolism and fat oxidation in humans.
- Conditions
- Aerobic Exercise, Acute Exercise, Circadian Rhythm Sleep-Wake Disorders, Unspecified Type, Glucose Metabolism
- Trial name
- DIVA (NCT05369715)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Chronobiology, Light
Light Timing Study
Chronic circadian misalignment and sleep restriction peak during late adolescence, and are associated with morning daytime sleepiness, poor academic performance, conduct problems, depressed mood, suicidal ideation, substance use…
- Conditions
- Chronobiology, Light, Sleep, Circadian Rhythm
- Trial name
- ALT (NCT04753190)
- Testing
- Baseline Sleep Satiation and Phase Stabilization, Gradually Shifted Sleep
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Major Depression
Chronos: the Use of Chronobiological Treatment in Depression
The primary objective of the present study is to examine whether the combination of the antidepressant duloxetine and chronotherapeutic methods (including sleep deprivation, light therapy, and maintaining a regular sleep-wake…
- Trial name
- NCT00149110
- Testing
- Sleep deprivation, Light therapy, Diurnal rhythms
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Hillerod Hospital, Denmark
Circadian Rhythm, Copeptin Blood Levels
The Circadian Rhythm of Copeptin
The circadian rhythm of copeptin will be examined in healthy subjects.
- Trial name
- Co-Rhythm (NCT02604875)
- Testing
- observation
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cardiac Rhythm Disorder, Bradycardia
The LEADLESS II IDE Study for the Aveir VR Leadless Pacemaker System
prospective, non-randomized, multi-center, international clinical study is designed to confirm the safety and effectiveness of the Aveir LP System in a subject population indicated for a VVI(R) pacemaker.
- Trial name
- NCT04559945
- Testing
- Aveir VR Leadless Pacemaker System
- Where
- 53 sites in United States, Canada and 6 more
- Volunteers
- 1,276 people
- Sponsor
- Abbott Medical Devices
Sleep Disturbance, Circadian Rhythm Sleep Disorders
Effect of an Eye Mask-Based Blackout Protocol on Sleep Quality and Melatonin
Sleep disturbance is a common problem among patients hospitalized in intensive care units due to continuous light exposure, noise, and frequent medical interventions.
- Conditions
- Sleep Disturbance, Circadian Rhythm Sleep Disorders, Intensive Care Unit Patients
- Trial name
- NCT07385768
- Testing
- Eye Mask-Based Blackout Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
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