Clinical trials: Rhytides
Wrinkles in Decolletage
An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area
This is a prospective open-label study to evaluate safety and effectiveness of two different reconstitution volumes of poly-l-lactic acid (PLLA) for correction of wrinkles in the décolletage area.
- Trial name
- NCT05538728
- Testing
- poly-l-lactic acid (Sculptra)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Wrinkle Reduction
Pivotal Study of the Cutera truSculpt Radiofrequency Device for Wrinkle Reduction
The purpose of this pivotal investigation is to evaluate the safety and efficacy of the Cutera truSculpt™ radiofrequency (RF) Device for Wrinkle Reduction.
- Trial name
- NCT03285581
- Testing
- truSculpt RF
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Benign Pigmented Lesions, Facial Wrinkles
PicoWay™ 730 Resolve Fusion for Benign Pigmented Lesions and Wrinkles
Evaluation of the PicoWay™ Laser System With 730nm and Resolve™ Fusion Handpieces for Treatment of Benign Pigmented Lesions and Wrinkles.
- Trial name
- NCT03774849
- Testing
- PicoWay™ 532nm fractional handpiece, PicoWay™ 730nm wavelength, PicoWay™ 1064nm fractional handpiece
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Candela Corporation
Nasolabial Folds, Marionette Lines
Emervel for the Correction of Lower Face Wrinkles & Folds
This study is designed to 1. evaluate the naturalness of facial expressions in motion (2D video images), by treating investigator assessment 2.
- Conditions
- Nasolabial Folds, Marionette Lines, Wrinkles
- Trial name
- NCT02718040
- Testing
- Emervel Classic and/or Deep Treatment Group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Cheek, Wrinkle
Open Label Extension for 43USSA1812
To evaluate long-term safety and effectiveness data of Sculptra Aesthetic beyond the Month 12 duration of the pivotal study 43USSA1812 (NCT04124692) to help characterize the long-term safety and effectiveness profile of the more…
- Trial name
- NCT04595331
- Testing
- Sculptra Aethestic reconsituted with 8ml Sterile Water for Injection
- Where
- 13 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Facial Rhytides, Crow's Feet Lines
Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines and Frown Lines
This study will evaluate the safety and efficacy of botulinum toxin type A compared to placebo for the treatment of Crow's Feet Lines and Frown Lines (Facial Rhytides) for patients who successfully completed Study 191622-099.
- Conditions
- Facial Rhytides, Crow's Feet Lines, Glabellar Lines
- Trial name
- NCT01224015
- Testing
- normal saline, onabotulinumtoxinA 44 U, onabotulinumtoxinA 24 U
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 684 people
- Sponsor
- Allergan
Rosacea, Wrinkles
Safety and Efficacy of the Luxe Device to Treat Facial Wrinkles and Rosacea
This study is designed to evaluate the efficacy and safety of the Luxe™ device for use in wrinkle and rosacea treatment. Up to 60 subjects will treat their periorbital and cheek areas daily for 4 weeks and then twice a week for…
- Trial name
- NCT01618864
- Testing
- Luxe
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Décolleté Wrinkles
A Study of Octave System for Improving Lines and Wrinkles of the Décolleté
To demonstrate the safety and effectiveness of the Octave System for improving lines and wrinkles of the décolleté.
- Trial name
- NCT04681352
- Testing
- Octave-Ultherapy treatment
- Where
- 10 sites in United States
- Volunteers
- 99 people
- Sponsor
- Merz North America, Inc.
Wrinkles
Comparison of Two Botulinum Toxins Type A on Forehead Wrinkles
Single-centre, controlled, randomized, evaluator-blinded, bilateral (split-face) comparison study in subjects with moderate to severe forehead wrinkles.
- Trial name
- NCT01014871
- Testing
- Botulinum Toxin Type A - Azzalure, Botulinum Toxin Type A - Vistabel
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Galderma R&D
Facial Rhytides
Reliability of the Facial Wrinkle Scale in Japanese Subjects
This study will evaluate the inter-rater and intra-rater reliability of the Facial Wrinkle Scale with Asian Photonumeric Guide (FWS-A) in Japanese subjects.
- Trial name
- NCT01600729
- Testing
- No Intervention
- Where
- Japan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Allergan
Glabellar Rhytides
Treatment With Botulinum Toxin Type A (BOTOX®) in Chinese Patients With Moderate to Severe Frown Lines
A study to evaluate safety and efficacy of treatment with botulinum toxin Type A (BOTOX®) in Chinese patients with moderate to severe frown lines (Glabellar Rhytides) previously treated with facial laser resurfacing.
- Trial name
- NCT01814670
- Testing
- botulinum toxin Type A
- Where
- China
- Volunteers
- 185 people
- Sponsor
- Allergan
Facial Rhytides, Crow's Feet Lines
Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines and Frown Lines
This study will evaluate the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of Crow's Feet Lines and Frown Lines (Facial Rhytides)
- Conditions
- Facial Rhytides, Crow's Feet Lines, Glabellar Lines
- Trial name
- NCT01189760
- Testing
- onabotulinumtoxinA 24 U, onabotulinumtoxinA 44 U, normal saline
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 917 people
- Sponsor
- Allergan
Skin Laxity
Radio Frequency Microneedling for Suprapatellar Skin
The human skin aging process is characterized by thinning dermis, atrophy of the extracellular matrix, and reduced collagen synthesis.
- Trial name
- NCT03507036
- Testing
- Profound system
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Bilateral Nasolabial Fold Wrinkles
Safety and Efficacy Study of Isolagen TherapyTM in the Treatment of Nasolabial Fold Wrinkles
The purpose of this study is to evaluate the safety profile and the treatment effect of Isolagen TherapyTM compared with placebo when administered to bilateral nasolabial fold wrinkles.
- Trial name
- NCT00649428
- Testing
- Autologous Human Fibroblast (azficel-T)
- Where
- 7 sites in United States
- Volunteers
- 203 people
- Sponsor
- Castle Creek Biosciences, LLC.
Wrinkles in Frontal Area
Field of Effects of Two Commercial Preparations of Botulinum Toxin Type A
The objective of this study is to compare the field of effects of the botulinum toxins (Dysport® and Botox®) using two equivalence-ratios and to gather supportive information, such as more detailed data on the effectiveness in…
- Trial name
- NCT00989768
- Testing
- Botulinum Toxin Type A (Dysport®), Botulinum Toxin Type A/Botox®, Botulinum Toxin Type A/Dysport®
- Where
- Brazil
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Pigmentation, Wrinkle
Post Market Clinical Follow Up Study to Collect Additional Data and Imaging
The intended use of the PicoSure device with focus lens array used in this study is to assess images to support additional marketing claims for the treatment of pigmentation and mild to moderate wrinkles.
- Trial name
- NCT04881058
- Testing
- RF Non-Invasive Treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cynosure, Inc.
Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
A Study to Evaluate Participant Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment
The objective of this study is to quantify the psychological and emotional impact of comprehensive aesthetic treatment with a portfolio of Allergan products by measuring the change in participant's satisfaction with facial…
- Trial name
- NCT03712449
- Testing
- JUVÉDERM®, BOTOX Cosmetic®, BELKYRA®
- Where
- 7 sites in Canada
- Volunteers
- 59 people
- Sponsor
- Allergan
Facial Wrinkles
Cryo-Touch II for the Treatment of Wrinkles
This is a prospective, non-randomized study to evaluate the performance of the MyoScience Cryo-Touch II device for the treatment of wrinkles.
- Trial name
- NCT01167140
- Testing
- Cryo-Touch II
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Upper Facial Lines (Glabellar Lines, Forehead Lines, & Lateral Canthal Lines)
Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Upper Facial Lines
This is a Phase 2, multicenter, open-label, single-arm study to evaluate the efficacy and safety of DaxibotulinumtoxinA for injection (DAXI for injection) in the treatment of Glabellar Lines (GL), Dynamic Forehead Lines (FHL)…
- Trial name
- NCT04259086
- Testing
- DaxibotulinumtoxinA for injection
- Where
- 8 sites in United States, Canada
- Volunteers
- 48 people
- Sponsor
- Revance Therapeutics, Inc.