Clinical trials: Rib Fracture Multiple, open to volunteers
Rib; Fracture
RibFix Blu Thoracic Fixation System Versus Non-surgical Treatment in Non-flail Chest Rib Fractures
This is a prospective, multi-center, observational, cohort study involving skilled cardiothoracic surgeons who are experienced in implanting the treatment of non-flail chest rib fractures and the use of RibFix Blu Thoracic…
- Trial name
- NCT05146986
- Testing
- Non surgical and Surgical
- Where
- 5 sites in Australia, South Korea
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Rib Fractures
INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures
This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple…
- Trial name
- NCT05642026
- Testing
- Ropivacaine, Non steroidal anti-inflammatory drug and opioids
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Zachary Warriner
Pain, Postoperative, Rib Fracture Multiple
Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures
To determine if patients with intraoperative cryoablation have better analgesia results compared to the control group of Surgical Stabilization of Rib Fractures (SSRF) without cryoablation
- Trial name
- NCT05415384
- Testing
- Cryoablation of Intercostal Nerves, Standard surgical treatment of patients with multiple rib fractures
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Rib Fracture, Rib Fracture Multiple
Zimmer Biomet-RibFix Titan
Prospective, single-center, non-randomized, single-cohort, post-market clinical follow-up study to confirm the safety, performance, and clinical benefits for the use of the RibFix Titan™ system implants and instrumentation) in…
- Trial name
- NCT07485829
- Testing
- The RibFix Titan™ device should be used within this arm of the study.
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Zimmer Biomet
Discitis of Thoracic Region
Parascapular Sub Iliocostalis Plane Block Versus Thoracic Paravertebral Plane Block for Traumatic Multiple Rib Fractures
Pain control of rib fractures is essential for not only primary pain relief but also preventing secondary complications such as atelectasis or pneumonia which increase the hospital stay, as well as the transition to chronic pain.
- Trial name
- NCT07493473
- Testing
- Thoracic paravertebral block, Parascapular Sub-Iliocostalis Plane Block
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Zagazig University
Rib Fractures, Rib Fracture Multiple
UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture
Traumatic rib fractures (i.e., broken ribs caused by a physical injury) are common and very painful. They also often lead to serious complications, more time spent in hospital, and can even lead to death.
- Conditions
- Rib Fractures, Rib Fracture Multiple, Rib; Fracture, With Flail Chest, Pain
- Trial name
- UNPIN (NCT05865327)
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Rib Fracture Multiple
Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures
This study is a single center, randomized controlled trial examining the effect of serratus anterior plane block (SAPB) on pain, PIC scores and other clinical outcomes in emergency department patients with multiple rib fractures…
- Trial name
- NCT05748366
- Testing
- Serratus Anterior Plane Block (SAPB), Standard Analgesic Medications
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- WellSpan Health
Multiple Rib Fractures
Role of Nerve Block in Management of Multiple Rib Fractures
Epidemiology \& Impact Thoracic trauma is a common and serious injury worldwide-especially in developing countries-and carries high rates of morbidity and mortality.
- Trial name
- NCT06958549
- Testing
- Nerve block with Lidocain, pharmacological analgesics
- Volunteers
- 74 people
- Sponsor
- Assiut University
Erector Spinae Block, Edge of Laminar Block
Continuous Erector Spinae Block Versus Continuous Edge of Laminar Block on The Quality of Analgesia and Diaphragmatic Excursion in Patients With Multiple Rib Fractures
This prospective randomized clinical trial aims to compare the effect of continuous erector spinae plane block versus continuous edge of laminar block on the quality of analgesia and diaphragmatic excursion in patients with…
- Conditions
- Erector Spinae Block, Edge of Laminar Block, Analgesia, Diaphragmatic Excursion
- Trial name
- NCT07069101
- Testing
- Erector spinae block, Edge of lamina block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Rib Fractures
Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs
In our study, we assess the diaphragmatic function, pain quality and anti-inflammatory properties between low dose infusion of dexmedetomidine normal saline in patients with multiple fracture ribs on conservative treatment.
- Trial name
- NCT04928300
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Rib Fractures, Spirometry
Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures
In patients admitted following a trauma, the incidence of multiple rib fractures is reported to be 9,7%, and this can be even higher in high energy trauma like motor vehicle accidents (1).
- Trial name
- NCT05105399
- Testing
- Serratus plane block (continuous or single-shot)
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Niguarda Hospital
Trauma, Rib Fractures
Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures
The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes.
- Conditions
- Trauma, Rib Fractures, Chest Wall Disorder, Respiratory Insufficiency
- Trial name
- NCT06533904
- Testing
- Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Rib Fracture, Rib Fracture Multiple
Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic Trauma
Thoracic trauma frequently involve rib fractures which can be very painful for 2-3 months. Unfortunately, pain is not simply a "symptom" of the injuries, but a significant cause of additional medical problems: pain causes people…
- Trial name
- NCT06069154
- Testing
- Cryoneurolysis, Local anesthetic peripheral nerve block
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Rib Fractures
Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures
Rib fractures cause a significant amount of pain and are associated with an increased risk of lung infections, long hospitalization, and increased cost.
- Trial name
- NCT07145346
- Testing
- Suzetrigine (SUZ)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Irvine
Multiple Rib Fractures, Isolated Blunt Thoracic Trauma
GNRI and PNI for Predicting Short-Term Outcomes in Older Adults With Multiple Rib Fractures
This prospective observational cohort study will evaluate whether the Geriatric Nutritional Risk Index (GNRI) and Prognostic Nutritional Index (PNI) can predict short-term clinical outcomes in adults aged 65 years or older with…
- Trial name
- NCT07823712
- Where
- Turkey (Türkiye)
- Volunteers
- 294 people
- Sponsor
- Ankara Etlik City Hospital
Pain Management, Rib Fracture Multiple
Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures
The goal of this observational study is to learn about the long-term effects of the serratus anterior plane block (SAPB) in adult patients who suffered multiple unilateral anterolateral rib fractures within 24 hours of patient…
- Conditions
- Pain Management, Rib Fracture Multiple, Serratus Anterior Plane Block
- Trial name
- SAPB (NCT07032766)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Albert Einstein College of Medicine
Rib Fractures
Ultrasound-Guided Mid-Point Transverse Process to Pleura Block Versus Thoracic Paravertebral Block for Pain Management in Patients With Multiple Rib Fractures (A Prospective Randomized Double- Blinded, Non-inferiority Trial )
The aim of our study is to investigate whether the analgesic effect of MTPB is non inferior to that of TPVB in trauma patients with multiple rib fractures.
- Trial name
- NCT06981728
- Testing
- Mid point transverse to pleura block
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rib Fracture Multiple, Flail Chest
Surgery for Unstable Chest Wall Injuries - How Many Fractures Should be Fixed?
The goal of this prospective, randomized study is to learn about the effects of two different surgical techniques for treating unstable chest wall injuries in adults.
- Trial name
- NCT07338656
- Testing
- Surgical stabilization of two fractures per rib, Surgical stabilization of one fracture per rib.
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital