Clinical trials: Right Heart Dysfunction
Right Ventricular Dysfunction
New Echocardiographic Methods for Right Ventricular Function.
Aims of this study are the evaluation of new echocardiographic methods (3D/4D- and strain-echocardiography) for measurement of the right ventricular (RV) function .
- Trial name
- NEW-RV (NCT01230294)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Pulmonary Embolism, Pulmonary Hypertension
Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE
To determine whether peripheral low dose systemic thrombolysis (PLST) is non-inferior to catheter directed acoustic pulse thrombolysis (ACDT) in improving RV function and reducing pulmonary artery pressures in submassive…
- Conditions
- Pulmonary Embolism, Pulmonary Hypertension, Thromboembolism, Right Ventricular Dysfunction
- Trial name
- NCT03581877
- Testing
- Alteplase, EKOS
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Northwell Health
Right Ventricular Dysfunction
Right Ventricular Function Changes After CIED Implantation: The RIGHT-CIED Study
This study aims to understand how the right side of the heart changes in people who receive an implantable cardiac electronic device (CIED), such as a pacemaker, ICD, or CRT device.
- Trial name
- RIGHT-CIED (NCT07272395)
- Testing
- Multimodal Right Ventricular Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Pacemaker-Induced Cardiomyopathy, Tricuspid Regurgitation
Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term.
Conventional pacemakers involve placing a lead through a valve into the bottom right chamber of the heart. Research has shown that this approach is associated with an increased risk of valve dysfunction, mortality, and impairment…
- Conditions
- Pacemaker-Induced Cardiomyopathy, Tricuspid Regurgitation, Right Ventricular Dysfunction
- Trial name
- LvL-PACE (NCT07534917)
- Testing
- Temporary left bundle branch area pacing, Temporary leadless right ventricular pacing
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Bradycardia
The Effects of Selective Site Right Ventricular Pacing
This is a pilot study into the effects on heart function when pacing the right ventricle (RV). This study aims to enrol a population with structurally normal hearts.
- Trial name
- PacingRV (NCT02153242)
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Left Ventricular Dysfunction, Right Ventricular Dysfunction
A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System
This study is to collect data and learn more about the Vscan Ultrasound Imaging System. It is an "observational" study with no additional procedures or intervention prescribed other than using the Vscan along with a routine…
- Conditions
- Left Ventricular Dysfunction, Right Ventricular Dysfunction, Pulmonary Hypertension, Heart Valve Diseases
- Trial name
- NCT01076296
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- GE Healthcare
Sick Sinus Syndrome, Heart Failure, Congestive
SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular Conduction
SAVE PACe is a large, prospective, single-blinded, randomized clinical trial with the main objective to study the effect of unnecessary right ventricular apical pacing on the clinical outcome of time to development of persistent…
- Conditions
- Sick Sinus Syndrome, Heart Failure, Congestive, Atrial Fibrillation, Bradycardia
- Trial name
- SAVEPACe (NCT00284830)
- Testing
- Implantable Pulse Generators
- Where
- 67 sites in United States, Canada
- Volunteers
- 1,070 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Aortic Valve Disorder
2D Strain of Right Ventricle in Peroperative of Cardiac Surgery
Evaluation of the right ventricle (RV) deformation (strain) with 2D speckle tracking technics obtained by echocardiographies (TEE) in peroperative period of cardiac surgery .
- Trial name
- NCT03298932
- Testing
- Aortic valve surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Non-severe Pulmonary Embolism, Pulmonary Embolism
Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study
The objective of the study is to evaluate the prognostic performance of the chair lift test in the initial assessment of the severity of non-severe pulmonary embolism in hospitalized patients, in comparison with the current…
- Conditions
- Non-severe Pulmonary Embolism, Pulmonary Embolism, Non-high-risk Pulmonary Embolism, Pulmonary Embolism Acute
- Trial name
- SIT-EP (NCT06166329)
- Testing
- chair lift test
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Rouen
Right Ventricular Dysfunction, Stroke Volume Index
Relationship Between Strain and Stroke Volume in Cardiac Surgery
Patients undergoing coronary artery bypass grafting up tp 30% will develop postoperative right ventricle dysfunction. Its imperative for the physician to fully understand the severity of this complication in order to perform an…
- Conditions
- Right Ventricular Dysfunction, Stroke Volume Index, Longitudinal Heart Strain
- Trial name
- NCT04694378
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center
Ventricular Arrythmia, Right Ventricular Dysfunction
Cardiovascular Consequences in Intense and Extended Physical Exercise
This research study because you participate in long distance triathlon of Embrun. In recent years, there has been a craze for races at increasingly longer distances (ultra-endurance) with risks to the cardiovascular system poorly…
- Trial name
- PHILIPPIDES (NCT03972865)
- Testing
- EmbrunMan race
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Right Ventricular Dysfunction, Cardiac Arrest
Emergency Department Assessment of Right Ventricular Function and Size in the Post Cardiac Arrest Patient
The right side of the heart of often overlooked in patients who are acutely unwell, as the main area of focus when performing echocardiography tends to be the left ventricle.
- Trial name
- NCT03309852
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of Manitoba
Right Ventricular Dysfunction, Pneumonectomy; Status
Right Ventricle Function After Major Right Lung Resection
Major lung resection is associated with high post-operative morbidity and mortality and significant long-term decreased functional capacity, especially due to cardiorespiratory complications.
- Trial name
- RIVER (NCT04167241)
- Testing
- Echocardiography
- Volunteers
- 50 people
- Sponsor
- Humanitas Clinical and Research Center
Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension
Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance
PERSEUS is an academic, investigator-initiated, multicenter observational registry of adults with acute pulmonary embolism (PE), promoted by Azienda Ospedaliero-Universitaria Careggi (Florence, Italy).
- Conditions
- Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension, Right Ventricular Dysfunction, Pulmonary Embolism (PE)
- Trial name
- PERSEUS (NCT07855679)
- Testing
- Routine clinical care (no study intervention)
- Where
- 16 sites in Italy, Poland and 1 more
- Volunteers
- 5,000 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Right Ventricular Dysfunction
Right Ventricular Haemodynamic Evaluation and Response to Treatment
Mono-center Study to evaluate different multimodal functional parameter of the right ventricle in PAH-patients
- Trial name
- Rightheart I (NCT03403868)
- Testing
- conductance catheter
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Giessen
COPD, Emphysema
Right Ventricular Diastolic Dysfunction
Heart-lung interactions remain misunderstood whereas pulmonary and cardiac pathologies are very commonly associated. Emphysema by increasing intrathoracic pressure appears to affect cardiac function.
- Conditions
- COPD, Emphysema, Right Heart Dysfunction
- Trial name
- RVDD (NCT04467242)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Covid19, Left Ventricular Dysfunction
Cardiac Dysfunction in Critically Ill Patients With COVID-19
Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically ill patients infected with COVID-19.
- Conditions
- Covid19, Left Ventricular Dysfunction, Right Ventricular Dysfunction, Pulmonary Hypertension
- Trial name
- CARDYCOVID (NCT04524234)
- Testing
- Echocardiography
- Where
- 5 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Sahlgrenska University Hospital
Right Ventricular Dysfunction
Right Ventricular Dysfunction in Cardiac Surgery Patients
To establish the correlation between echocardiographic parameters of the RV, measured with TEE and the right ventricular ejection fraction (thermodilution).
- Trial name
- NCT03183414
- Testing
- echocardiographic measurements
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Frisius Medisch Centrum
Pulmonary Embolism
Risk Stratification and Prognostic Value of Right Ventricular Dysfunction Screening Using Transthoracic Echocardiography in Acute Pulmonary Embolism
This observational study evaluates right ventricular dysfunction in patients with acute pulmonary embolism using transthoracic echocardiography and assesses its prognostic significance and risk stratification value.
- Trial name
- RVD-PE (NCT07647497)
- Testing
- Transthoracic Echocardiography
- Where
- 2 sites in Egypt
- Volunteers
- 112 people
- Sponsor
- Sohag University
Asthma, Pulmonary Disease, Chronic Obstructive
Right Heart Dysfunction and Pulmonary Hypertension Evaluation in Airway Disease Using Cardiac Magnetic Resonance
Poor function of the right side of the heart and rise in pressure of the blood vessels leading to the lungs are two main heart-related factors that are associated with worsening of airway disease.
- Trial name
- RiPAIR (NCT02865577)
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Leicester