Clinical trials: Right Side
Right Heart Failure, Pulmonary Hypertension
Body Volume Regulation in Pulmonary Arterial Hypertension With Right Ventricular Failure
Secondary hyperaldosteronism and the non-osmotic release of arginine vasopressin (AVP) are the major factors in sodium and water retention in pulmonary arterial hypertension with right ventricular failure.
- Trial name
- NCT00811486
- Testing
- Spironolactone and conivaptan
- Where
- United States
- Sponsor
- University of Colorado, Denver
Tricuspid Regurgitation, Right Ventricular Dilatation
Pharmacological Reduction of Right Ventricular Enlargement
Functional tricuspid regurgitation (TR) has been regarded as a secondary phenomenon of heart failure (HF), mitral valve (MV) disease or atrial fibrillation.
- Trial name
- PROVE (NCT04345796)
- Testing
- Carvedilol+Empagliflozin, Carvedilol, Empagliflozin
- Where
- 3 sites in South Korea
- Volunteers
- 56 people
- Sponsor
- Asan Medical Center
Transesophageal Echocardiography
Estimation of Pulmonary Arterial Pressure With Transesophageal Echocardiography: a Pilot Study
Transesophageal echocardiography (TEE) plays an important role in intraoperative monitoring and can be used to estimate pulmonary artery pressures.
- Trial name
- NCT03117673
- Testing
- transesophageal echocardiography measurements
- Where
- Austria
- Volunteers
- 39 people
- Sponsor
- Medical University of Vienna
Ventilation Therapy; Complications, Right Ventricular Function
Effect of Airway Pressure Release Ventilation on Right Ventricular Function Assessed by Transthoracic Echocardiography
Effects of APRV on right ventricular function in patients with acute respiratory distress syndrome by transthoracic echocardiography
- Conditions
- Ventilation Therapy; Complications, Right Ventricular Function, ARDS, Transthoracic Echocardiography
- Trial name
- NCT05414110
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Altitude Hypoxia
Effect of Acetazolamide on Right Heart Function During Exercise in Lowlanders Older Than 40 Years at Altitude
Randomized, placebo controlled trial evaluating efficacy of acetazolamide on right heart function during exercise in lowlanders older than 40 years travelling from 760 m to 3'100 m.
- Trial name
- NCT03537924
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Major Depression
Electroconvulsive Therapy (ECT) for Elderly Patients With Major Depression
ECT (electroconvulsive therapy) is mostly given to patients between the age of 60 - 85 years. There is limited evidence on the efficacy and cognitive side-effects of right unilateral (RU) and bifrontal (BF) electrode positions…
- Trial name
- NCT01559324
- Testing
- ECT
- Where
- Norway
- Volunteers
- 92 people
- Sponsor
- Diakonhjemmet Hospital
Tricuspid Valve Disease
Characteristics and Prognosis of Moderate or Severe Tricuspid Regurgitation
The tricuspid valve : its evaluation is relatively difficult in echocardiography and the management of tricuspid valve diseases remains poorly codified.
- Trial name
- EPIT (NCT03546231)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Atrioventricular Block, Left Bunde Branch Area Pacing
Left Bundle Branch Area Pacing Versus Right Ventricular Pacing in Atrioventricular Block With Preserved Ejection Fraction
Conventional right ventricular pacing (RVP) has been associated with ventricular dyssynchrony and an increased risk of pacing-induced cardiomyopathy, which may lead to worse clinical outcomes.
- Conditions
- Atrioventricular Block, Left Bunde Branch Area Pacing, Conduction System Pacing
- Trial name
- NOVEL II (NCT07464041)
- Testing
- Left Bundle Branch Area Pacing, Right venticular pacing
- Where
- 4 sites in South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Pulmonary Embolism (PE), Pulmonary Embolism With Right Ventricle Enlargement
Pilot Study Evaluating Catheter Directed Thrombolysis Device in Acute Intermediate Risk Pulmonary Embolism
This is a pilot study of the Flow Medical Catheter, a catheter-based device used to deliver clot-dissolving medication directly to a blood clot in the lungs (pulmonary embolism).
- Trial name
- PE (NCT07681154)
- Testing
- Thrombolysis Catheter
- Volunteers
- 20 people
- Sponsor
- Flow Medical Solutions, Inc.
Extended Ileal Resection Under Laparotomy, Total Proctocolectomy Under Laparotomy
Postoperative Analgesia in Abdominal Surgery: a Medico-economic Study
Background : Epidural anaesthesia is associated in abdominal surgery with reduced pain and postoperative respiratory complications together with quicker recovery of bowel function.
- Conditions
- Extended Ileal Resection Under Laparotomy, Total Proctocolectomy Under Laparotomy, Colectomy Left/Right/Total Under Laparotomy, Rectosigmoidal Resection Under Laparotomy
- Trial name
- PERIDIGE (NCT01470846)
- Testing
- epidural analgesia, PCA
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Limoges
Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension
Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance
PERSEUS is an academic, investigator-initiated, multicenter observational registry of adults with acute pulmonary embolism (PE), promoted by Azienda Ospedaliero-Universitaria Careggi (Florence, Italy).
- Conditions
- Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension, Right Ventricular Dysfunction, Pulmonary Embolism (PE)
- Trial name
- PERSEUS (NCT07855679)
- Testing
- Routine clinical care (no study intervention)
- Where
- 16 sites in Italy, Poland and 1 more
- Volunteers
- 5,000 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Aphasia, Cerebrovascular Accident
Role of the Right Brain in Recovery of Language Function in Chronic Stroke
This study will examine in healthy individuals and in patients with aphasia (a language disturbance that is usually caused by stroke, brain disease, or injury) which parts of the brain are involved in naming everyday objects.
- Trial name
- NCT00076479
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Right Heart Failure
Assessing Outcomes in ED Patients With RV Failure
Millions of Americans seek emergency care for acute shortness of breath, and many undergo computerized tomographic pulmonary angiography (CTPA) testing that is negative for acute disease.
- Trial name
- NCT03073629
- Testing
- Clinical Pathway
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Indiana University
Sports Physical Therapy
Comparative Effects of Getting it Right Addressing Shoulder Pain and Rotator Cuff Strengthening Exercise Military Sports
This research will use a randomized clinical trial (RCT) method to get military athletes with rotator cuff tendinopathy. People will be chosen at random to either get the GRASP method or normal exercises for making the shoulder…
- Trial name
- NCT06828081
- Testing
- Range of Motion Exercises, Strengthening exercises with theraband
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cicatrix
Anti-Scarring Efficacy and Safety of Intradermal Juvista (Avotermin) in Healthy Males
This study was undertaken to investigate safety and scar-improvement activity of different applications of Juvista (avotermin), administered to surgical incisions made to the skin of a healthy population of male volunteers aged…
- Trial name
- NCT00594581
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Renovo
Pulmonary Arterial Hypertension
A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension
The primary objective of this study is to assess the effect of early and rapid treprostinil therapy for mean pulmonary artery pressure (mPAP) reduction to improve right ventricular (RV) function and reverse RV remodeling in…
- Trial name
- ARTISAN (NCT05203510)
- Testing
- Parenteral Treprostinil, Oral Treprostinil
- Where
- 28 sites in United States
- Volunteers
- 52 people
- Sponsor
- United Therapeutics
Myocardial Injury, Connective Tissue Diseases
Effect of Sacubitril/Valsartan on Reduced Right Ventricular Ejection Fraction in Patients With CTD
Heart failure, one of the leading causes of connective tissue disease (CTD) mortality, has attracted increasing attention. Currently, no known study had focused on the effect of sacubitril/valsartan on right ventricular…
- Trial name
- EARLY-MYO-CTD (NCT04197050)
- Testing
- Sacubitril / Valsartan Oral Tablet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Acute Abdomen, Emergency Surgery
Primary Cecal Pathologies Presenting as Acute Abdomen
Background: The importance of cecal pathologies lie in the fact that being the first part of large intestine, any disease involving the cecum affects overall functioning of the large bowel.
- Conditions
- Acute Abdomen, Emergency Surgery, Laparotomy, Amoebic Colitis
- Trial name
- NCT03262025
- Testing
- Operated
- Volunteers
- 43 people
- Sponsor
- Jawaharlal Nehru Medical College
Tetralogy of Fallot, Pulmonary Insufficiency
Contrast Enhanced 3D Echocardiographic Quantification of Right Ventricular Volumes in Repaired CHD
We propose the novel integration of two echocardiographic technologies - three-dimensional echocardiography using semi-automated right ventricular analysis coupled with the administration of ultrasound enhancing agents - to…
- Trial name
- NCT05186415
- Testing
- Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nemours Children's Clinic
Depression, Major Depressive Disorder
Left vs. Right Non-Inferiority Trial
The aim of this study is to test the hypothesis that low-frequency rTMS (LFR) works as well as the established intermittent thetaburst rTMS (iTBS) treatment for treatment resistant depression (TRD).
- Conditions
- Depression, Major Depressive Disorder, Major Depressive Episode
- Trial name
- LeRNIT (NCT04999553)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Intermittent Theta Burst Stimulation (iTBS), Low Frequency Right (LFR)
- Where
- 2 sites in Canada
- Volunteers
- 480 people
- Sponsor
- University of British Columbia
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