Clinical trials: Right Side
End Stage Heart Failure
Sildenafil for the Prevention of Right Heart Failure Following LVAD Implantation
Continuous-flow left ventricular assist devices (LVAD) move blood from the left ventricle (the largest chamber of the heart) to the aorta (the body's main artery) to help the heart better meet the needs of the body and to improve…
- Trial name
- NCT03356353
- Testing
- Sildenafil Citrate
- Where
- 4 sites in Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Pulmonary Embolism
Pulmonary Embolism: Multifunctional Assessment of Prognosis
This is a prospective, observational, multicenter study. The primary aim of the study is to assess the accuracy of spiral CT scan to detect right ventricular dysfunction as compared to current 'gold standard'in patients with…
- Trial name
- PE-MAP (NCT01113775)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Of Perugia
Central Venous Catheter Placement
Supraclavicular Fossa US View for Catheter Positioning in Right Subclavian Central Venous Catheterization
The study will evaluate if the supraclavicular fossa ultrasound view can be used to achieve a correct catheter tip placement in infraclavicular right subclavian central venous catheter placement.
- Trial name
- NCT03812757
- Testing
- Supraclavicular fossa US scanning
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Skane University Hospital
Healthy Subjects
A Multiple Use Tolerability Study of a Breathe Right Nasal Strip Prototype
This study evaluated the safety \& tolerability of two Breathe Right nasal strip prototypes. Prototypes were produced as an improvement to the currently marketed product.
- Trial name
- NCT01495494
- Testing
- Marketed Nasal Strip, Prototype Nasal Dilator
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cyanotic Congenital Heart Disease, Right Ventricular Outflow Tract Obstruction
RVOT Stenting Versus Surgical RV-PA Conduit in Cyanotic Adults
This prospective observational cohort study aims to compare clinical and hemodynamic outcomes of percutaneous right ventricular outflow tract stenting versus surgical right ventricle-to-pulmonary artery conduit placement in…
- Trial name
- NCT07866911
- Volunteers
- 30 people
- Sponsor
- Assiut University
Pulmonary Embolism, Embolism
Aventus Thrombectomy System Pulmonary Embolism Clinical Study
Evaluate the safety and efficacy of the Aventus Thrombectomy System for aspiration thrombectomy in subjects with acute pulmonary embolism.
- Conditions
- Pulmonary Embolism, Embolism, Embolism and Thrombosis, Vascular Diseases
- Trial name
- NCT05907564
- Testing
- Thrombectomy
- Where
- 26 sites in United States
- Volunteers
- 120 people
- Sponsor
- Inquis Medical, Inc.
Medication Administered in Error, Medication Adverse Effects
Identifying Drug-related Problems at ED Triage (DRP-EDiT) V1
Up to a third of patients who visit emergency departments (EDs) do so because they have an issue with medicines prescribed by their doctor or purchased over the counter.
- Conditions
- Medication Administered in Error, Medication Adverse Effects, Medication Reaction
- Trial name
- DRP-EDiT (NCT05476705)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Tricuspid Regurgitation, Right Ventricular Dysfunction
Tricuspid Regurgitation Study
The effect of cardiac pacing leads on tricuspid regurgitation is unclear. This study will determine whether using a smaller diameter leads and an alternate position in the ventricle, the proximal septum, will reduce tricuspid…
- Conditions
- Tricuspid Regurgitation, Right Ventricular Dysfunction, Left Ventricular Dysfunction
- Trial name
- NCT01093001
- Testing
- Echo
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Mayo Clinic
Heart Disease
Sildenafil in Single Ventricle Patients
Patients with single ventricle anatomy undergo staged surgical palliation. The result is an "in series" circulation with pulmonary blood flow and cardiac output directly related to pulmonary vascular resistance.
- Trial name
- NCT01169519
- Testing
- Sildenafil by injection
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Sick Sinus Syndrome, Heart Failure, Congestive
SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular Conduction
SAVE PACe is a large, prospective, single-blinded, randomized clinical trial with the main objective to study the effect of unnecessary right ventricular apical pacing on the clinical outcome of time to development of persistent…
- Conditions
- Sick Sinus Syndrome, Heart Failure, Congestive, Atrial Fibrillation, Bradycardia
- Trial name
- SAVEPACe (NCT00284830)
- Testing
- Implantable Pulse Generators
- Where
- 67 sites in United States, Canada
- Volunteers
- 1,070 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Pacemaker DDD
Right Ventricular Septal Versus Apical Pacing: Echocardiographic Study
This study aims to compare the effect right ventricular apical versus septal pacing on left ventricular function by deformation imaging using 2D speckle tracking echocardiography.
- Trial name
- NCT06045143
- Testing
- Patients undergoing DDD pacemaker implantation
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Surgery--Complications, Congestive Heart Failure
The Clinical Significance of Portal Hypertension After Cardiac Surgery: a Multicenter Prospective Observational Study
Portal flow pulsatility detected by Doppler ultrasound is an echographic marker of cardiogenic portal hypertension from right ventricular failure and is associated with adverse outcomes based on previous studies performed at the…
- Conditions
- Surgery--Complications, Congestive Heart Failure, Right Heart Failure, Anesthesia
- Trial name
- TECHNO-MULTI (NCT03656263)
- Testing
- Doppler assessment of portal vein flow
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- Montreal Heart Institute
Systolic Function
Strain Analysis as a Right Ventricle Contractility Marker
The analysis of the systolic function (contractility) of the right ventricle (RV) is fundamental and central in many pathologies in intensive care unit. It can guide physicians in choosing therapeutics.
- Trial name
- NCT03090204
- Testing
- ultrasound measurements
- Where
- 2 sites in France
- Volunteers
- 16 people
- Sponsor
- Hospices Civils de Lyon
Major Depressive Disorder (MDD)
6 Weeks Right-Amygdala TIS for Depression
The current investigation employs a directed neuromodulation technique, specifically targeting the right amygdala, to ascertain its therapeutic efficacy in managing depressive episodes.
- Trial name
- NCT07059143
- Testing
- Nervio-X
- Where
- 3 sites in China
- Volunteers
- 38 people
- Sponsor
- Ruijin Hospital
Right Heart Failure
Predictive Value of Vasodilator Challenge for Right Heart Failure After LVAD Implantation
Prospective evaluation of the predictive value for post-LVAD right ventricular failure (RHF) of pulmonary vasodilator challenge, in addition to current laboratory, echocardiographic and haemodynamic parameters.
- Trial name
- PREVV-RHF-LVAD (NCT05836233)
- Testing
- Pulmonary Vasodilators
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- San Camillo Hospital, Rome
Exercise-induced Myocardial Damage, Right Ventricular Diastolic Dysfunction
Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.
It is well known that scar tissue on the heart muscle can cause (life-threatening) arrhythmias. However, the exact cause of this scar tissue is not entirely clear.
- Trial name
- NCT06715748
- Testing
- Ketone Monoester (KE)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Sudden Cardiac Death, Congenital Heart Disease
Sudden Cardiac Death in Systemic Right Ventricle
In complete transposition of the great arteries (TGA) with previous atrial switch repair, and congenitally corrected transposition of the great arteries (ccTGA), the morphological right ventricle and its tricuspid valve continue…
- Conditions
- Sudden Cardiac Death, Congenital Heart Disease, Transposition of Great Vessels
- Trial name
- STARSII (NCT03833843)
- Testing
- imaging
- Where
- France
- Volunteers
- 1,240 people
- Sponsor
- European Georges Pompidou Hospital
Postoperative Complications, Heart Failure
Association Between Portal Flow Pulsatility and Right Ventricular Dysfunction in the Postoperative Period of Cardiac Surgery
Right ventricular dysfunction (RVD) after cardiac surgery is associated with ischemia and myocardial injury. While echocardiographic measures like Tricuspid Annular Plane Systolic Excursion (TAPSE) are frequently used to assess…
- Trial name
- LIFESAVE (NCT06777355)
- Testing
- Transthoracic and Transesophageal echography within 24 hours post cardiac surgery
- Where
- France
- Volunteers
- 32 people
- Sponsor
- CMC Ambroise Paré
Pulmonary Embolism (PE), Right-to-Left Shunt
Pulmonary Embolism and Right-to-Left Shunts
Every fetus has a small hole in their heart, called a foramen ovale when they are developing in the womb. For most people this hole closes shortly after birth, but it doesn't close completely in 1 out of every 4 people.
- Conditions
- Pulmonary Embolism (PE), Right-to-Left Shunt, Stroke, Atrial Septal Defects
- Trial name
- PEaRLS (NCT07519876)
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Tufts Medical Center
Cardiac Pacing, Pacing Therapy
Ventricular Electrical Synchronization by Stimulating Left and Right Bundle Branches Area in Pacing-indicated Patients
This is a prospective, single-site, non-randomized, acute feasibility clinical study. The purpose of this study is to explore the electrocardiogram (ECG) characteristics of simultaneous stimulation of right and left bundle…
- Conditions
- Cardiac Pacing, Pacing Therapy, Pacemaker
- Trial name
- NCT04023890
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
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