Clinical trials: Right Ventricular Dysfunction
Right Ventricular Dysfunction
Right Ventricular Haemodynamic Evaluation and Response to Treatment
Mono-center Study to evaluate different multimodal functional parameter of the right ventricle in PAH-patients
- Trial name
- Rightheart I (NCT03403868)
- Testing
- conductance catheter
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Giessen
COPD, Emphysema
Right Ventricular Diastolic Dysfunction
Heart-lung interactions remain misunderstood whereas pulmonary and cardiac pathologies are very commonly associated. Emphysema by increasing intrathoracic pressure appears to affect cardiac function.
- Conditions
- COPD, Emphysema, Right Heart Dysfunction
- Trial name
- RVDD (NCT04467242)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Covid19, Left Ventricular Dysfunction
Cardiac Dysfunction in Critically Ill Patients With COVID-19
Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically ill patients infected with COVID-19.
- Conditions
- Covid19, Left Ventricular Dysfunction, Right Ventricular Dysfunction, Pulmonary Hypertension
- Trial name
- CARDYCOVID (NCT04524234)
- Testing
- Echocardiography
- Where
- 5 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Sahlgrenska University Hospital
Right Ventricular Dysfunction
Right Ventricular Dysfunction in Cardiac Surgery Patients
To establish the correlation between echocardiographic parameters of the RV, measured with TEE and the right ventricular ejection fraction (thermodilution).
- Trial name
- NCT03183414
- Testing
- echocardiographic measurements
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Frisius Medisch Centrum
Pulmonary Embolism
Risk Stratification and Prognostic Value of Right Ventricular Dysfunction Screening Using Transthoracic Echocardiography in Acute Pulmonary Embolism
This observational study evaluates right ventricular dysfunction in patients with acute pulmonary embolism using transthoracic echocardiography and assesses its prognostic significance and risk stratification value.
- Trial name
- RVD-PE (NCT07647497)
- Testing
- Transthoracic Echocardiography
- Where
- 2 sites in Egypt
- Volunteers
- 112 people
- Sponsor
- Sohag University
Right Heart Insufficiency, Tricuspid Regurgitation
Application of FAPI Visualization in the Assessment of Right Ventricular Dysfunction Due to Volume Overload
\"Bicuspid aortic stenosis represents the most prevalent form of cardiac valve disease, primarily resulting from degenerative alterations and rheumatic conditions that disrupt mitral valve function.
- Trial name
- NCT06663566
- Testing
- Diagnose the patients right heart function as well as right heart fibrosis, Diagnose the patient's right heart function as well as right heart fibrosis
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Anzhen Hospital
Pulmonary Arterial Hypertension, Acute Respiratory Failure
Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertension-Associated Acute Respiratory Failure
This is a single center, retrospective, propensity score matching cohort study that explores the efficacy and safety of high flow nasal cannula and non-invasive ventilation in the treatment of acute respiratory failure associated…
- Conditions
- Pulmonary Arterial Hypertension, Acute Respiratory Failure, High-flow Nasal Cannula, Noninvasive Ventilation
- Trial name
- HFCNV-PAH (NCT06582459)
- Testing
- HFNC treatment, NIV treatment
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First People's Hospital of Neijiang
Blood Pressure, Right Ventricular Dysfunction
Effect of a Higher Blood-pressure on Right Ventricular Function
Right ventricular (RV) dysfunction in cardiac surgery is an independent risk factor for morbidity and mortality. Raising the systemic blood pressure with norepinephrine seems to have a positive influence on the right ventricular…
- Trial name
- NCT03806582
- Testing
- Norepinephrine
- Where
- Netherlands
- Volunteers
- 78 people
- Sponsor
- Frisius Medisch Centrum
Right Ventricular Dysfunction, Right Heart Failure
Right Ventricular Pressure Waveform Monitoring in Cardiac Surgery
RV dysfunction has been associated with increased mortality in the ICU and cardiac surgical patients. Thus, early identification of RV dysfunction at less severe stages will allow for earlier intervention and potentially better…
- Conditions
- Right Ventricular Dysfunction, Right Heart Failure, Congestive Heart Failure
- Trial name
- PACEPORT (NCT04092855)
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- Montreal Heart Institute
Pulmonary Hypertension, Thromboembolism, Pulmonary
Perioperative Portal Vein Pulsatility as a Postoperative Prognostic Indicator in Pulmonary Endarterectomy
The investigators aim to evaluate the utility of portal vein pulsatility as a predictor of the composite outcome of persistent organ dysfunction plus death in patients undergoing elective or urgent pulmonary endarterectomy for…
- Conditions
- Pulmonary Hypertension, Thromboembolism, Pulmonary, Perioperative/Postoperative Complications, Venous Hypertension
- Trial name
- PVP-ETO-CPC (NCT03197792)
- Testing
- All patients
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Psoriatic Arthritis (PsA), Subclinical Right Ventricular Systolic Dysfunction
Right Ventricular Strain in Detecting Subclinical Right Ventricular Systolic Dysfunction in Psoriatic Arthritis Patients: Relation to Serum Endostatin Level
The aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain echocardiography
- Trial name
- NCT07046312
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulmonary Embolism
Short-term Clinical Deterioration After Acute Pulmonary Embolism
This is a prospective, observational, multicenter cohort study to compare right ventricular dysfunction dependent and independent prognostic models for short-term serous adverse events in patients who are diagnosed with pulmonary…
- Trial name
- NCT03915925
- Where
- 6 sites in United States
- Volunteers
- 935 people
- Sponsor
- Wake Forest University Health Sciences
Pulmonary Arterial Hypertension, Right Heart Failure
Repurposing Valsartan May Protect Against Pulmonary Hypertension
This is a Phase 2, single-center, randomized placebo controlled trial of valsartan (an angiotensin receptor blocker) in adults with pulmonary arterial hypertension.
- Conditions
- Pulmonary Arterial Hypertension, Right Heart Failure, Right Ventricular Dysfunction, Pulmonary Vascular Disorder
- Trial name
- REVAMP-PH (NCT06053580)
- Testing
- Valsartan 40 mg
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Right Ventricular Dysfunction
TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR
Three-dimensional echocardiography has become a gold standard to assess right ventricular (RV) function, and investigators plan to use 3D transesophageal echocardiography to assess RV function in 3 types of aortic valve…
- Trial name
- NCT05804240
- Testing
- 3D TEE RVEF
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Thomas Jefferson University
Pulmonary Hypertension
Targeting the Right Ventricle in Pulmonary Hypertension
This study is looking to see if giving ranolazine to subjects on stable pulmonary hypertension specific therapies but with right ventricular dysfunction (RVEF <45%) would improve their outcome.
- Trial name
- NCT01839110
- Testing
- Ranolazine
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Pennsylvania
Ventricular Dysfunction, Asthma in Children
Evaluation of Cardiac Biomarkers and Ventricular Function in Asthmatic Children
Evaluation of cardiac biomarkers and the left and right ventricular systolic and diastolic function in asthmatic children in Assuit university hospital
- Trial name
- NCT05985720
- Volunteers
- 50 people
- Sponsor
- Assiut University
Bradyarrhythmias, Arrhythmias
Safety and the Effects of Isolated Left Ventricular Pacing in Patients With Bradyarrhythmias
Previous experimental and clinical studies have consistently suggested that right ventricular (RV) apical pacing has important adverse effects.
- Conditions
- Bradyarrhythmias, Arrhythmias, Atrioventricular Block, Ventricular Dysfunction
- Trial name
- SAFE-LVPACE (NCT01717469)
- Testing
- Left ventricular pacing through coronary sinus tributaries (Attain StarFix), Right ventricular pacing (Medtronic)
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- University of Sao Paulo
AV Block
Left Septal Pacing or Left Bundle Branch Pacing to Avoid Left Ventricle Systolic Dysfunction
Right ventricular apical pacing (RVAP) can produce left ventricular dysfunction (LVD). Conduction system pacing (CSP) has been used successfully to reverse LVD in patients with left bundle branch block.
- Trial name
- STAY II (NCT06707662)
- Testing
- Pacemaker and defibrillator
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Parc de Salut Mar
Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction
Feasibility of Non-invasive Hemodynamic Assessment by 5D Flow in Congenital Heart Disease
This study evaluates whether new flow parameters of the cardiac magnetic resonance imaging (MRI) allow evaluation of parameters for which usually invasive rigth-left heart catheterization are necessary.
- Conditions
- Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction, Fontan Circulation
- Trial name
- NCT07742046
- Testing
- Right-left heart catheterization in magnetic resonance imaging (MRI)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Tobias Rutz
Heart Block, Sick Sinus Syndrome
Impact of Septal Vs Apical Pacing on Right and Left Ventricular Performance
The study aims to use cardiac MRI scans and analysis techniques to evaluate differences in cardiac function after 12 months of pacing in patients with pacing leads placed in different positions within the right ventricle…
- Conditions
- Heart Block, Sick Sinus Syndrome, Atrioventricular Block, Ventricular Dysfunction
- Trial name
- NCT01798043
- Testing
- Cardiac MRI with pacemaker stimulation, Cardiac MRI with and without pacemaker stimulation
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Abbott Medical Devices